Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name HEM2
Systematic Name YGL040C
Alias OLE4, SLU1
Strain S288c
Description Aminolevulinate dehydratase; a homo-octameric enzyme, catalyzes the conversion of 5-aminolevulinate to porphobilinogen, the second step in heme biosynthesis; enzymatic activity is zinc-dependent; localizes to the cytoplasm and nucleus; human homolog ALAD can complement yeast hem2 mutant
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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>HEM2 YGL040C
ATGCATACAGCTGAATTTTTGGAAACAGAACCAACAGAAATCTCATCTGTTCTAGCAGGT
GGTTATAATCACCCACTGCTGAGACAGTGGCAAAGTGAGCGTCAACTGACTAAGAACATG
TTGATTTTTCCGCTATTCATCTCCGATAATCCAGATGACTTTACTGAAATTGACTCTCTA
CCTAATATCAATAGAATCGGTGTAAATAGGCTAAAAGACTACTTAAAGCCATTAGTGGCC
AAGGGTTTGCGTTCTGTGATCTTGTTTGGTGTGCCTCTCATCCCTGGTACCAAGGATCCA
GTGGGTACAGCGGCTGACGATCCTGCAGGGCCAGTCATTCAAGGTATTAAATTCATTCGT
GAGTATTTCCCTGAACTGTATATTATTTGCGATGTCTGTCTCTGTGAATACACTTCTCAT
GGCCATTGCGGGGTTCTATACGATGATGGTACTATTAATAGAGAACGTAGTGTCTCTAGA
TTAGCAGCTGTGGCAGTTAACTACGCTAAAGCTGGTGCGCACTGTGTGGCTCCCAGTGAT
ATGATCGATGGTAGGATCAGAGATATTAAACGAGGCTTAATAAATGCAAACTTGGCTCAC
AAGACCTTCGTGTTATCCTATGCAGCTAAGTTTAGCGGTAATCTATATGGGCCATTCCGT
GATGCTGCTTGTTCAGCTCCTTCGAATGGTGATAGGAAATGTTACCAATTACCTCCTGCC
GGTCGTGGCCTGGCACGTAGGGCGTTGGAAAGGGATATGAGTGAAGGTGCCGACGGTATT
ATTGTTAAGCCTTCCACTTTCTACTTAGATATAATGAGGGATGCAAGTGAAATTTGTAAA
GACTTACCAATCTGCGCATATCACGTGTCGGGCGAATACGCAATGTTACATGCTGCAGCT
GAAAAAGGTGTTGTTGATTTGAAGACAATTGCCTTTGAATCTCATCAAGGTTTCTTGAGG
GCGGGTGCCAGATTAATCATCACTTATTTGGCTCCTGAGTTCCTAGACTGGTTAGATGAA
GAAAACTAA
Promoter Sequence
Download FASTA
>HEM2 YGL040C
GATTCTATTGAAACGACACCATACAGCTCATACGAGTCCGGTGTACTGGCACAGAACACA
GATGACAATACAAAAGTAAATAAATCTATCGACAGCAATTCCTATTTTCTTTTACATTTA
TATTGATTAGCTTACGATTTCTGTATTTATAGAGCGTGTAGTTACATATCCAGATACCTG
TCTTCTAGGTGAACAGTTGGTTTTCAGTTCAAAAATTATATAGGATCTTGGACGGTTAGC
TTTCCTCCTCATGATCCACTCTTTCGGGAACAAGATAAATTATTGTTTAGTTTTGATTAG
CTTTACTTTAATTCGCACAAAAAAAAGCCTGCATTGTCACGAGAACATTGAAACATATAC
AAAAAACAAATTTGAAATAGAAAACAAAGCAATTTACAGAAATGACTGCCTGGTGCTAAT
TCTTGCATATATTTTATTTTTAATTAACTAGAAATCAGCGTCAATTATAGTTTCTGGTGA
GTCAGCCAATGTCTGTAAATAAAAACAATATGCTTAAGAGGATTAACAGTGGCACAAGAG
GCAAAGAAGGGAAGAAGGCGTACACGTCCACATGAATATATAAAAAAGAAGTGTTACATC
AATTGGAACCCATCTTTCGGAACGTTTTCTATCTGCTACAAGCCTGTGTCACCGAATTAC
TTTATTGGGTCTTGTAGAGACGCCGAAATACATCATCATTCCAAGATCGACGATAAAAAT
CATCCAAAAAATTGTTGCCGAAAAAAAAATTGGAAAAGGTGAAAAAAAAATCAAAATACG
GGTAAACGAGCAATCCCTGTTCGGTGCGGTGATTGGCTTGAGGCAAGCTTCCCGCTTGAT
TTATATAAGAGTAAGGCAACCTAATAAATGCTAGCAACATCTATGCGCCACTCTATTGTC
TTTGATTTTCTTGCCCAATCAGCCAAATAAAAAAAAGTTTTACTGCTTACTCATATTATT
GCTTACTCCAGTAATTCATACCTAGAAAATTGACAAAACC
Chr coordinates Chr VII from 420555-419527
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