Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Standard Name
PYC1
Systematic Name
YGL062W
Strain
S288c
Description
Pyruvate carboxylase isoform; cytoplasmic enzyme that converts pyruvate to oxaloacetate; differentially regulated than isoform Pyc2p; mutations in the human homolog are associated with lactic acidosis; PYC1 has a paralog, PYC2, that arose from the whole genome duplication
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>PYC1 YGL062W
ATGTCGCAAAGAAAATTCGCCGGCTTGAGAGATAACTTCAATCTCTTGGGTGAAAAGAAC
AAAATATTGGTGGCTAATAGAGGAGAAATTCCAATCAGAATTTTTCGTACCGCTCATGAA
CTGTCTATGCAGACGGTAGCTATATATTCTCATGAAGATCGTCTTTCAACGCACAAACAA
AAGGCTGACGAAGCATACGTCATAGGTGAAGTAGGCCAATATACCCCCGTCGGCGCTTAT
TTGGCCATTGACGAAATCATTTCCATTGCCCAAAAACACCAGGTAGATTTCATCCATCCA
GGTTATGGGTTCTTGTCTGAAAATTCGGAATTTGCCGACAAAGTAGTGAAGGCCGGTATC
ACTTGGATTGGCCCTCCAGCTGAAGTTATTGACTCCGTGGGTGATAAGGTCTCAGCTAGA
AACCTGGCAGCAAAAGCTAATGTGCCCACCGTTCCTGGTACACCAGGTCCTATAGAAACT
GTAGAGGAAGCACTTGACTTCGTCAATGAATACGGCTACCCGGTGATCATTAAGGCCGCC
TTTGGTGGTGGTGGTAGAGGTATGAGAGTCGTTAGAGAAGGTGACGACGTGGCAGATGCC
TTTCAACGTGCTACCTCCGAAGCCCGTACTGCCTTCGGTAATGGTACCTGCTTTGTGGAA
AGATTCTTGGACAAGCCAAAGCATATTGAAGTTCAATTGTTGGCCGATAACCACGGAAAC
GTGGTTCATCTTTTCGAAAGAGACTGTTCCGTGCAGAGAAGACACCAAAAGGTTGTCGAA
GTGGCCCCAGCAAAGACTTTACCCCGTGAAGTCCGTGACGCCATTTTGACAGATGCAGTT
AAATTGGCCAAAGAGTGTGGCTACAGAAATGCGGGTACTGCTGAATTCTTGGTTGATAAC
CAAAATAGACACTATTTCATTGAAATTAATCCAAGAATCCAAGTGGAACATACCATCACA
GAAGAAATTACCGGTATAGATATTGTGGCGGCTCAGATCCAAATTGCGGCAGGTGCCTCT
CTACCCCAGCTGGGCCTATTCCAGGACAAAATTACGACTCGTGGCTTTGCCATTCAGTGC
CGTATTACCACGGAAGACCCTGCTAAGAACTTCCAACCAGATACCGGTAGAATAGAAGTG
TACCGTTCTGCAGGTGGTAATGGTGTTAGACTGGATGGTGGTAACGCCTATGCAGGAACA
ATAATCTCACCTCATTACGACTCAATGCTGGTCAAATGCTCATGCTCCGGTTCCACCTAC
GAAATCGTTCGTAGAAAAATGATTCGTGCATTAATCGAGTTCAGAATTAGAGGTGTCAAG
ACCAACATTCCCTTCCTATTGACTCTTTTGACCAATCCAGTATTTATTGAGGGTACATAC
TGGACGACTTTTATTGACGACACCCCACAACTGTTCCAAATGGTTTCATCACAAAACAGA
GCCCAAAAACTTTTACATTACCTCGCCGACGTGGCAGTCAATGGTTCATCTATCAAGGGT
CAAATTGGCTTGCCAAAATTAAAATCAAATCCAAGTGTCCCCCATTTGCACGATGCTCAG
GGCAATGTCATCAACGTTACAAAGTCTGCACCACCATCCGGATGGAGGCAAGTGCTACTA
GAAAAGGGGCCAGCTGAATTTGCCAGACAAGTTAGACAGTTCAATGGTACTTTATTGATG
GACACCACCTGGAGAGACGCTCATCAATCTCTACTTGCAACAAGAGTCAGAACCCACGAT
TTGGCTACAATCGCTCCAACAACCGCACATGCCCTTGCAGGTCGTTTCGCCTTAGAATGT
TGGGGTGGTGCCACATTCGATGTTGCAATGAGATTTTTGCATGAGGATCCATGGGAACGT
TTGAGAAAATTAAGATCTCTGGTGCCTAATATTCCATTCCAAATGTTATTGCGTGGTGCC
AATGGTGTGGCTTATTCTTCATTGCCTGACAATGCTATTGACCATTTCGTCAAGCAAGCC
AAGGATAATGGTGTTGATATATTTAGAGTCTTTGATGCCTTAAATGACTTGGAACAATTG
AAGGTCGGTGTAGATGCTGTGAAGAAGGCAGGTGGTGTTGTAGAAGCCACTGTTTGTTTC
TCTGGGGATATGCTTCAGCCAGGCAAGAAATACAATTTGGATTACTACTTGGAAATTGCT
GAAAAAATTGTCCAAATGGGCACTCATATCCTGGGTATCAAAGATATGGCAGGTACCATG
AAGCCAGCAGCTGCCAAACTACTGATTGGATCTTTGAGGGCTAAGTACCCTGATCTCCCA
ATACATGTTCACACTCACGATTCTGCAGGTACTGCTGTTGCATCAATGACTGCGTGTGCT
CTGGCGGGCGCCGATGTCGTTGATGTTGCCATCAACTCAATGTCTGGTTTAACTTCACAA
CCATCAATCAATGCTCTGTTGGCTTCATTAGAAGGTAATATTGACACTGGTATTAACGTT
GAGCATGTCCGTGAACTAGATGCATATTGGGCAGAGATGAGATTGTTATACTCTTGTTTC
GAGGCTGACTTGAAGGGCCCAGATCCAGAAGTTTATCAACATGAAATCCCAGGTGGTCAA
TTGACAAACTTGTTGTTTCAAGCCCAACAATTGGGTCTTGGAGAACAATGGGCCGAAACA
AAAAGAGCTTACAGAGAAGCCAATTATTTATTGGGTGATATTGTCAAAGTTACCCCAACT
TCGAAGGTCGTTGGTGATCTGGCACAATTTATGGTCTCCAATAAATTAACTTCCGATGAT
GTGAGACGCCTGGCTAATTCTTTGGATTTCCCTGACTCTGTTATGGATTTCTTCGAAGGC
TTAATCGGCCAACCATATGGTGGGTTCCCAGAACCATTTAGATCAGACGTTTTAAGGAAC
AAGAGAAGAAAGTTGACTTGTCGTCCAGGCCTGGAACTAGAGCCATTTGATCTCGAAAAA
ATTAGAGAAGACTTGCAGAATAGATTTGGTGATGTTGATGAGTGCGACGTTGCTTCTTAT
AACATGTACCCAAGAGTTTATGAAGACTTCCAAAAGATGAGAGAAACGTATGGTGATTTA
TCTGTATTGCCAACAAGAAGCTTTTTGTCTCCACTAGAGACTGACGAAGAAATTGAAGTT
GTAATCGAACAAGGTAAAACGCTAATTATCAAGCTACAGGCTGTGGGTGATTTGAACAAA
AAGACCGGTGAAAGAGAAGTTTACTTTGATTTGAATGGTGAAATGAGAAAAATTCGTGTT
GCTGACAGATCACAAAAAGTGGAAACTGTTACTAAATCCAAAGCAGACATGCATGATCCA
TTACACATTGGTGCACCAATGGCAGGTGTCATTGTTGAAGTTAAAGTTCATAAAGGATCA
CTAATAAAGAAGGGCCAACCTGTAGCCGTATTAAGCGCCATGAAAATGGAAATGATTATA
TCTTCTCCATCCGATGGACAAGTTAAAGAAGTGTTTGTCTCTGATGGTGAAAATGTGGAC
TCTTCTGATTTATTAGTTCTATTAGAAGACCAAGTTCCTGTTGAAACTAAGGCATGA
Promoter Sequence
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>PYC1 YGL062W
CTACGTGGGGCTATTGAGCGGTACCCTTAGCGGCTACTGCTTGTCGCCCTCGAAGCTGGA
CGCGTTTGAGGCAGCCATGCAGGAGTACGTGGGAACGCATAATTTTCACAACTTTACCAC
AGGAAAGCTTTGGGGGGATCCTAGTGCTCAGCGCCATATCAAAAAGGTTGTAGTGTCGCA
GGCCTCACCGGGATGGATATGTGTGCGGATCCACGGGCAGTCGTTTATGTTGCATCAGAT
TCGACGAATGGTAGCGCTTGCCGTACTTGCAGCCCGTTGCCAATTGCCGCCTAATATTGT
ACGTAACTATTTTAACGCCGGGCCTAGGAAATACATTCCGAGGGCGCCCGCACAAGGCCT
ATTATTAGAGGGACCTGTGTTTGACGGGTATAACACTAAGTTGCGCAATTTGCTGTATTG
CGAAATCCGCCCGGACGATATCACTCTTGAGCGCATGTGCCGTTTCCGAGAACGCCAGAT
CTGTACTGCGATCGCACACGAGGAGACACAGCGTCACGTGTTTTGCCATTTTGTACGACA
AATGAACCGCCTGGCCACGCCTCTAATCTAGCCGCCCAATGTCGCGGGTTGACCCGCGAC
ATTGGGCGGGCAATACTCTCATCTTATTGGCTATTCAACTTAGACAAGCGCCAGTTGCGC
GCACAAATTTGGTCATGACCGCTCCACCGGCATGCGTGTCGTCATCCCGCATCATTCGGG
ACATTTTGGCCTTTTCCGCAGTGCGTAGTTGACGTGGGGAGAAAGCTAGTGGGCTGTCGC
ATATGGTTGGTTTTAGGTGGCGAAAGTTTCGCCGCGATAGCAATCATGTCCTCGACCTTA
ATCTCAATGGAATGGGTCATGCTCGGTAAGTGAGTCTCGCTGTATATAAGTATATATGTA
ATCGCCTAGTTCGATAGATACAAGGAGGTCTTGAGTATGTAGATAAACGAAAAGAAGATA
ACAAAAGGAAAATCTCAGCCTCTCCCCTTCCTCTTAGACA
Chr coordinates
Chr VII from 385196-388732