Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
AFT1 Systematic Name
YGL071W Alias
RCS1 Strain
S288c Description
Transcription factor involved in iron utilization and homeostasis; binds consensus site PyPuCACCCPu and activates transcription in response to changes in iron availability; in iron-replete conditions localization is regulated by Grx3p, Grx4p, and Fra2p, and promoter binding is negatively regulated via Grx3p-Grx4p binding; AFT1 has a paralog, AFT2, that arose from the whole genome duplication; relative distribution to the nucleus increases upon DNA replication stress External sources
Open in SGD
Open in KEGG
Gene Sequence
Download FASTA Hide Seq
>AFT1 YGL071W
ATGGAAGGCTTCAATCCGGCTGACATAGAACATGCGTCACCGATTAATTCATCTGACAGC
CATTCATCCTCCTTTGTATATGCTCTACCCAAAAGTGCTAGTGAATATGTAGTCAACCAT
AATGAGGGTCGTGCAAGTGCAAGTGGAAATCCAGCCGCAGTGCCGTCTCCCATAATGACA
CTGAATCTCAAAAGCACACATTCCCTCAATATTGATCAGCATGTTCATACCTCAACATCG
CCGACGGAAACTATTGGGCATATTCATCATGTGGAAAAGCTGAATCAAAACAATTTGATT
CATCTGGATCCAGTACCCAACTTTGAAGATAAGTCCGATATTAAGCCTTGGTTGCAAAAG
ATTTTTTATCCTCAAGGAATAGAACTTGTGATAGAAAGGTCGGACGCATTTAAAGTTGTC
TTCAAGTGTAAAGCTGCTAAAAGGGGAAGGAACGCGAGAAGGAAAAGAAAAGATAAGCCC
AAAGGACAGGACCACGAAGACGAGAAATCCAAGATCAATGATGACGAATTAGAATATGCG
AGTCCTTCTAATGCCACAGTAACCAATGGGCCTCAAACATCGCCCGATCAAACATCCTCC
ATAAAGCCAAAGAAAAAAAGATGTGTATCGAGGTTTAATAACTGTCCGTTTAGAGTACGA
GCTACTTATTCGTTAAAGAGGAAAAGATGGAGCATTGTTGTAATGGACAATAACCATTCA
CATCAGCTAAAGTTTAACCCTGATTCCGAAGAGTACAAAAAATTCAAAGAAAAATTAAGA
AAGGATAATGACGTAGATGCAATCAAGAAATTCGACGAATTGGAATACAGAACTTTGGCC
AATTTGCCCATTCCAACAGCTACAATCCCCTGTGATTGTGGTTTAACAAATGAAATACAA
AGTTTCAATGTCGTATTGCCCACTAACAGTAATGTTACTTCATCAGCATCCTCTTCAACT
GTATCGTCCATATCCCTTGATTCATCGAATGCATCTAAAAGGCCATGCTTACCCTCTGTA
AATAACACCGGTAGTATCAATACCAATAACGTAAGGAAACCGAAAAGCCAGTGTAAGAAT
AAAGACACACTCTTAAAAAGAACCACCATGCAGAACTTTCTCACAACTAAATCAAGGCTG
CGTAAGACCGGTACGCCAACATCTTCGCAACACTCATCTACAGCATTTTCAGGATATATT
GATGATCCTTTCAATTTGAATGAAATCTTGCCACTGCCGGCATCCGATTTCAAGCTAAAC
ACTGTAACAAATTTGAACGAAATTGACTTTACGAACATTTTTACCAAATCGCCGCATCCA
CATAGCGGGTCTACCCATCCAAGACAAGTCTTCGACCAATTGGACGATTGTTCCTCTATA
CTCTTCTCTCCATTAACTACAAACACGAATAATGAATTTGAAGGAGAGTCAGATGATTTT
GTTCATTCTCCATATTTGAACTCAGAGGCAGATTTCAGCCAAATTCTTAGTAGTGCTCCC
CCAGTCCATCATGACCCAAATGAAACACATCAGGAAAACCAGGATATTATTGATAGATTT
GCTAATAGTTCCCAAGAACATAATGAGTATATTCTACAATATTTGACGCACTCCGATGCT
GCTAACCACAATAACATCGGCGTTCCAAACAACAATTCACATTCGCTAAATACTCAGCAT
AACGTTTCTGATCTGGGCAACTCACTTTTAAGACAAGAAGCTTTAGTTGGCAGCTCTTCA
ACAAAAATCTTCGACGAATTGAAATTTGTACAAAATGGCCCACACGGTTCTCAACATCCT
ATAGATTTTCAACATGTTGACCATCGTCATCTCAGCTCTAATGAACCTCAAGTACGATCA
CATCAATATGGTCCGCAACAGCAGCCACCGCAGCAATTGCAATATCACCAAAATCAGCCC
CACGACGGCCATAACCACGAACAGCACCAAACAGTACAAAAGGATATGCAAACGCATGAA
TCGCTAGAAATAATGGGAAACACATTATTGGAAGAGTTCAAAGACATTAAAATGGTGAAC
GGCGAGTTGAAGTATGTGAAGCCAGAAGATTAG Promoter Sequence
Download FASTA
>AFT1 YGL071W
AATAACACTAGTGAGGGAAGTACAAGGGTGTCCCCCGATATAAAGTTCAGCGCCACTGAA
AACACTAAAGTGAGTGATAACCTGCCAAGCTTTAATGACCACAGTTATTCCACCCAGGCC
GACACGGCGCCCGAGAACGCTAAGAAAAGATTTGTGGAGGAAATACCGGAACCGGCTATA
GTCGAAATACAGGACCCGACAGAGTACAACGATCACCGCCTGCCCAAACGAGCTAAGAAA
TAGTACACAGGGCAAGGTCATTAAATAGCGTATATAATCATTTAATATAGTATGTTCTCG
AAGCTGATCGCGTAAGGCGCAGAGCGAACTAAAAAAAATACCGGCACCCATGCACCTCAC
ACCGCCGCACGCGAGTGAGGTTGAACTGCACCCGGAAAATGCCAAGTAGATGAGTCGTGA
AGAGTTCTCGTTATTCGAGCTAGTGAGAGCCTGAGAAGGGCTTGCCGAGTGAACTGGTGT
CACATTGGCCGTTTTAACGCAAGTTGGCGTACTTATATTGACTGTTGGATGAAAGGGTAA
TCAAGAGAAACGGAAACGGCCTCCTCATCGTTAAGCTCATCAGTATTCATTTCTCCCCTT
TCTGCTCCATCGCGTGCTCGAGACTATATTCTTCAGATTATCAAGCAGAAACAGAATTCG
CATATTACATAACTTTCACAGGTTGAAGTATAAACCGCTACAGTACACAACCTCGGATAG
AATATAGGGAAGAGGCCAATTCCGTGAAAACGATTTAATATTCTTTACAGTTACAAAAAG
TATTACCTATTATCCTCTTTTCGGTGTCATTGACAAACCTCTTAGCGACAGAAACTCCCT
AGCAAAAGAGTAAATCCATAGGAACAACAAAAGAAGACAAATTATCATAATATAATTGGG
AGTGATAGACGACGATTCATGCTATACCGTAGGTTTTTGATACAAGTCTAACAGTTATAC
TATTTTTAAAAACAAAAAAATAACAGAAAAATCTACGACA
Chr coordinates
Chr VII from 372012-374084
