Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Standard Name
MPC1
Systematic Name
YGL080W
Alias
FMP37
Strain
S288c
Description
Highly conserved subunit of mitochondrial pyruvate carrier (MPC); MPC is a mitochondrial inner membrane complex that mediates pyruvate uptake and comprises Mpc1p and Mpc2p during fermentative growth, or Mcp1p and Mpc3p during respiratory growth; null mutant displays slow growth that is complemented by expression of human or mouse ortholog; mutation in human ortholog MPC1 is associated with lactic acidosis and hyperpyruvatemia
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>MPC1 YGL080W
ATGTCTCAACCGGTTCAACGCGCTGCAGCACGCTCATTCCTTCAAAAATACATCAATAAA
GAAACTTTGAAATATATTTTCACAACACACTTCTGGGGTCCCGTATCAAATTTCGGTATC
CCAATTGCTGCTATATATGATCTGAAAAAAGACCCTACACTAATCTCTGGCCCAATGACT
TTTGCTTTAGTTACCTATTCAGGTGTTTTCATGAAGTATGCTCTTTCAGTATCACCCAAA
AACTACTTACTGTTTGGATGCCACCTTATTAATGAAACTGCGCAATTAGCTCAAGGCTAT
AGGTTTCTCAAATACACGTATTTCACAACAGATGAGGAGAAGAAAGCTCTAGATAAGGAA
TGGAAAGAGAAAGAAAAAACTGGTAAACAGTAA
Promoter Sequence
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>MPC1 YGL080W
TAAACTTAGTGTCTGATGGGCCAAATGATGAAATTGATTTGAAAAATGGTGATGCTTTTG
GTTTGATTGCAATTGATAATCATCCTTTTCGCGACAACCATCATTTAGCCGCCAAGTTAA
TTTTCCGAATTGAACTTGAGTATTTCGATGAAGCAAGGGAAATCGTAAAGTGCACTATTA
CAAATGTAACATTTGGAAAGAATAATACAGTGTCATCTTTCCCTATTCATTCTGCAACAT
CCACAGAAGATAGCGATTCAAGTTGGTACGGATTGTCGGAAGCGAGTACGCAAACGGAAG
TTGCAGATGAGTGTCATGAAACGAACACCATATTGACTCGAGGTGGTAGGTTTTCTATCC
TTTCGTTGAGAAAAAGAGGCAGCAAGCAAGACCAGAAGATCTGCAGTAACTTTGATAGAA
AAATACATGAAACGAGTTCTTTCGAAGAAGAAATCGAAGTTTGCACTGACACAGACACCA
CAGAAGAAAAAGAAGAAGAAGAAGAAAAAGAAGAAGGGGATGATGAGGAAGGAGAAATAG
AACTTGAAATTATTAGAGTAAAAAGAATAAAGGGCAGGACGAAGATAAAGAAGACGCTTA
CTTGCTTCTCGAAAAACAAGAAAATTATTACCCCTCAGCACTCCAATAGTATGTGGTTAC
TACTAATAGTAATCTTGATTTTTGACCGCCTACTATCGAATTAAATATAATTTTATAACC
CAGTTCTATATTGCTGGGTGGTATTATAGCTTCATGGCTAGTCAAATAAGTGGAGTTTTT
TGCTCTGGACGTGGCCTGTAAAGTTCTCTTTTGCGACGGCCCCCCGCTTTAACCGAGGCG
AAATGACAAGTGCTTTCTGGCAAAGAAGGAATAGCCACTACAACCTGCGGTCTCCACCTT
TCTCCACCGATAATCTATTTAAACACTCACTTGCCAATCAGCAAACGTCAATACATCTAC
ATATATACGTATAGATTTTATTGCACTGTGATCAAAAAGA
Chr coordinates
Chr VII from 358636-359028