Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
MAD1 Systematic Name
YGL086W Strain
S288c Description
Coiled-coil protein involved in spindle-assembly checkpoint; required for inhibition of karyopherin/importin Pse1p (aka Kap121p) upon spindle assembly checkpoint arrest; phosphorylated by Mps1p upon checkpoint activation which leads to inhibition of anaphase promoting complex activity; forms a complex with Mad2p; gene dosage imbalance between MAD1 and MAD2 leads to chromosome instability External sources
Open in SGD
Open in KEGG
Gene Sequence
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Sequence hidden Promoter Sequence
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>MAD1 YGL086W
AATTTATCGATCTTGGGTGCAACAGTCTTTCTGTCGTCTGTTTTTTAGCAGATCTAAGGG
TTTACCTTCGTGTGCCCGGATGAGGACCGTTGCAAGGATTGATAATACAACTATATACAT
CATTATCGTAGTGAATTGCACGAGTAACTTCTCGGCATGGGGTGAGTAAATTCATATTAT
GAAAGTAATTAAACTTACTACCTAAATAAGAGGATATCTATGTCTTATTGCTTGTATATA
TGAGTGGCTTGGAATGCTGCAAATACTGTTTAGGAAAAAGTAGATAACTAAAAGGTTTCT
CCTTCCTTCGGTTGACGCAATTTCTTGTTCGCTGGGGTTGCCATTTCCTTTCTAAGATCA
AGTAATAAAGTTTCCATGGTGTAGGCTCTTTTCCAGTCACGTAAGGTGTGGAAGTCAGTT
TGGACCTCCCCCGTAGTTGGATTGACGCATGGTAGATTTATCTTGGAAATGAAAGTGACC
TTTGGGGGAGAATCTGGATAGTTTGGGCCACAATCTATAGAAAGGGAATAGATTCTGTTT
TCATGATTACTATGAGGGGGCCCTAAAATAGTGCCGTTCCATTTGGTCATGGTAATATCG
TCGCTATCAGCTAAACCATAACTACATGATTCTGGACCAAACCCTTTTTCACCCTTTTCT
AATTCTTCTAACAACCTAAAATTTCTTGGTCTGATTTACAATAGGACAGTGAGGGTACAT
TTCAAGAATTTGTTAGTATATGTTGAAATCCCTTTCAAAACTTATAATAACATACACTTT
TGACATTTTTGTGTAAACGCTGCTTTCTTCTACGTTGCATATACAGAATAAGAATTTCAC
CACGACATCGAAATGTAATGAGCAGAGATTGTGTAGGAAGTTGATCTTATTTTAGTCTCT
TATTTATCGCTAAAGGAGCAATGAAAATTGATAGCGTGTTACCCTAGGAATAATTCCTAA
CAATTTTTTCCATCTTAAAATCGAGAGGTAATAGTAAATA
Chr coordinates
Chr VII from 347119-349368
