Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
VPS45
Systematic Name
YGL095C
Alias
STT10, VPL28
Strain
S288c
Description
Protein of the Sec1p/Munc-18 family; essential for vacuolar protein sorting; required for the function of Pep12p and the early endosome/late Golgi SNARE Tlg2p; essential for fusion of Golgi-derived vesicles with the prevacuolar compartment; mutation in human VPS45 is associated with congenital neutropenia and primary myelofibrosis of infancy
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>VPS45 YGL095C
ATGAACCTTTTTGATGTGGCTGACTTTTATATAAACAAAATTGTGACTTCCCAATCGAAA
TTGAGCGTAGCCAATGTCAATGAACACCAAAGGATTAAGGTTTTGCTGTTGGATAAGAAT
ACCACACCTACGATATCCTTATGTGCCACTCAAAGTGAGTTGTTGAAGCATGAAATATAT
CTGGTAGAAAGAATAGAAAATGAGCAACGTGAAGTGTCCAGGCATTTAAGGTGCTTAGTT
TACGTTAAACCCACAGAGGAAACACTGCAACATCTGCTGCGTGAGTTAAGAAATCCTCGG
TACGGCGAGTATCAAATATTCTTTAGTAATATTGTCTCTAAATCTCAATTAGAACGGCTA
GCTGAATCTGACGACTTGGAAGCTGTTACTAAGGTGGAAGAAATATTCCAAGACTTTTTT
ATATTAAACCAAGATTTATTTTCGTTTGATTTGCAACCAAGAGAATTTTTAAGTAATAAA
TTGGTTTGGAGCGAAGGGGGGCTAACAAAATGTACCAACAGCTTAGTTTCTGTGCTTTTA
TCCTTAAAGATAAAACCAGATATCAGGTATGAAGGAGCAAGTAAAATTTGTGAAAGATTG
GCTAAAGAAGTTTCCTATGAGATTGGTAAAAACGAAAGAACTTTTTTTGATTTTCCTGTG
ATGGATTCGACACCTGTGTTACTAATTTTAGATCGTAATACTGATCCTATAACACCTTTA
CTTCAACCTTGGACCTACCAATCAATGATCAATGAGTATATAGGCATTAAGCGGAATATA
GTTGATTTATCGAAAGTGCCTAGAATTGATAAAGACCTGGAGAAGGTCACCTTATCATCA
AAGCAAGATGCTTTCTTCAGGGATACCATGTATTTGAATTTTGGTGAATTGGGTGATAAA
GTAAAACAATATGTGACTACATACAAAGACAAGACACAAACCAACAGCCAAATAAATTCC
ATTGAGGATATTAAAAACTTTATTGAGAAGTATCCAGAGTTTAGAAAATTATCTGGAAAT
GTTGCAAAGCATATGGCTATAGTGGGGGAATTAGACAGACAGTTGAAGATAAAAAATATA
TGGGAAATTAGTGAAATAGAACAAAATCTATCAGCACACGATGCCAATGAAGAAGATTTC
TCCGATTTGATTAAATTGCTACAAAATGAAGCAGTTGATAAGTATTACAAGTTAAAGCTT
GCATGTATTTATTCTTTAAACAATCAAACCAGCTCAGACAAAATCCGTCAACTAGTTGAG
ATTCTGTCTCAACAACTTCCTCCAGAGGACGTCAACTTTTTCCATAAATTTAAATCGCTT
TTTAGCCGCCAGGATAAAATGACTCAAAGTAACCATGACAAGGACGATATATTAACCGAA
CTAGCAAGAAGATTTAATAGTAGAATGAATTCTAAGAGCAACACCGCTGAAAACGTCTAT
ATGCAACATATTCCGGAAATTTCGTCATTACTAACAGATCTCTCTAAAAATGCGTTATTC
AGGGATCGTTTCAAAGAAATAGATACTCAAGGCCATAGAGTGATCGGAAACCAGCAGAGC
AAAGATATTCCTCAGGATGTAATATTGTTTGTTATTGGCGGTGTAACTTATGAGGAGGCA
AGGCTAGTCCATGATTTCAATGGAACGATGAATAACAGAATGAGGGTGGTTTTAGGAGGC
ACCTCTATACTTTCAACTAAAGAATATATGGATTCTATTAGATCTGCAAAATAA
Promoter Sequence
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>VPS45 YGL095C
TGGAGTACCATTTGTCGATGATTATGTGGTAAACACGAACCACATAGAAGACTATTTGAC
AAGATATAGTGGGATTCTTCCTGGTGACTTGGACCCTGAAAAGAGTACCAAAAGGCTTGT
GAGAAGAAACGTTGTATATCGAAAAGTCTGGCTTTTAATGCAGCTCGGATGCGTATTTGT
TGGTCATGGTTTGAATAATGACTTCAAACACATTAATATTAATGTCCCAAGAAACCAAAT
TCGCGACACTGCCATATATTTTCTACAAGGAAAGAGATATCTTTCATTGCGTTATCTGGC
ATATGTGTTGTTAGGAATGAATATCCAAGAGGGAAATCACGATTCAATTGAAGATGCCCA
TACTGCCTTGATTCTTTACAAAAAATATCTCCACCTGAAAGAAAAAGCTATCTTTGAGAA
AGTACTGAACAGCGTGTACGAAGAAGGAAGAGCCCATAATTTCAAAGTTCCAGAAACTTC
AAAGGGATAATATGGTGCAGTGCCTTTCACGTAATCTCAAGAGCCACCAGCGCACCACTG
GTTGGAAAAGTATACAAAAAATTCAAAAAAATTATAAAATGTTACCGGTGTTTGTGTACT
ATTATATATACTGTAATCAACATATGCAAACATTTTGAAACAGGTCTTGTTAAACCTTTT
TGTCATCACACGCCAGAATTAGACTTCTTTGTGCGATGAAGTAATATCTATTACCAGAAA
AGAAGGTCTTACCCTTGTTTGGCCTCTCATATGTTTCCTACTTGTTTCCCGGGCGTCCGT
AACGAGTACTGACTGTATGGCGAAAAGTTGCCAGAAATGTTCATTTTTGTTTCTGCCAAT
TTCAGGAAAGGGTAACGTCATTACAGTTAGTTAACGTTCGAACTTACTTATAGAAGTGCC
TTGGCTCATATGCAATGTACCCAGAGTAACATTAAGGAGTGAAGAGGTACAGTGACTTGG
TTTTGAGTTAAGGCCATCTTTTACTGTATAGAACAAAGAA
Chr coordinates
Chr VII from 330607-328874