Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name MON1
Systematic Name YGL124C
Alias AUT12
Strain S288c
Description Subunit of a heterodimeric guanine nucleotide exchange factor (GEF); subunit of the Mon1-Ccz1 GEF complex which stimulates nucleotide exchange and activation of Ypt7p, a Rab family GTPase involved in membrane tethering and fusion events at the late endosome and vacuole; GEF activity is stimulated by membrane association and anionic phospholipids; role in localizing Ypt7p to the vacuolar membrane; required for autophagy, the CVT pathway and mitophagy; potential Cdc28 substrate
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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>MON1 YGL124C
ATGAATCTCAATGAAAGCTACCTAGATGCTGAGATACCGAAGGGTCAATTGAAGCATAGT
AAAAGTGGGAATTTTGAGGGTATTCCAATCGTGGCAACGACTTCAGAACCAACGACATCG
GTTAATCTAGATGAAACATTCTTCAAGAAGGCGCCTATAGCAATGCCAATATGCGATGAT
CATTCTGTTAGTAAATCTACCTCTGTAAATTCTTTGAATACAACATCTTTGGCATCCAGA
AGATCTCCTTTGCAAACAAAAAAATTGCAAGCTAAAAATAATTTATTGTCAGCAGATTTG
GCAAAGAGCAATGATGATACAACGAGAGCACTAAACAGTCCAAAAAAGGATTTCGGTCCT
TATTTGGACAGCGAGAATGACATCAGGAGTCGCTTGGCCGAAAGCATATATTCTATGGAA
ACATCTATAAGAGGATCGGAACTACAGAGACGGCCGTACGTAAGTAACGAAATTCCTAAT
GTATTCAAGTTTTCGAAGTTCAATAGTAACTGCAAGTTAAATGAGAGCCAGACTCTCTGT
GACAAAAATTTCTTCATATTCACGTCAGCGGGTAAACCGATCTATTGCATGCACGGCAAA
GATGAACAGATCATGTCATATACAGGGCTCGTTAATACGGTAATAAGCTACTTCCAAGTC
AATGGACCATCGGAATTGAAAACTATATCCACTTTAACTTCTGGTAAAAGGCTTACTTTT
TTGGATAAATCACCTATATTACTAATGGCTCAATCCGAAAGAGGCGAGTCCTCGAACGAA
TTGTTGAATCAGTTGGATTTTTTATATTCGTATATTCTTTCGTCTTTAAGTGAACGCCAA
TTACTTAGGTTATTTTCCAAAAGAGAAAATTTCGACCTGAGAAATTATCTAGAAAGCACA
GATTTTGAAAATTTAGACGAAATATGTTCACTAATCTGTAACAGAATGTTCCCGGATTTA
CTATTGAACTCTTTACAATGCTTACCATTTAACCATTCTTCAAGATTAAAGTTGCAGAAT
GTGGTTTTACAGCAACTGGAGAAAAGGCAGGACATTCCCAGGGGGACCTTACTGTACGGC
TTGATAATTGCGCCTCAGAATAAATTGTGCTGTGTTCTTCGACCCAGAGGCCATACTTTA
CACACTACAGATTTACATCTTCTATTTTGCCTAATATCTCATCAATTTCAAAATTTAGAC
GAAACTCAGGAACTTTGGGTACCCATTTGTTTTCCCAAGTTCAATTCGAGTGGTTTTCTT
TATTGTTATATTAAGTTTCTACCTAATGATACTCACAGCAATGAGAAATCGGCACTAGTA
TTAATAAGTGCACAAAAGGATGCATTCTTTTCATTGAAGTCGTTTAGTGACGAGTTGATT
ATTAAACTCGAAGAAGAGAAGCTATTGAAAAAGATAAATACTTCAAAAGGGTTCAAGCTT
AGCGATATACCAGCACCAATGGTTCATCATTTCATATATAAATCGAAGCAAAACGTTCAA
TATGTTATGCCGCACTTCGAAGTCAACAGTAACATCGCACTGGATTCTTCACAGGGGCTA
GAATATGAATTGAAATTGAAGACATACTACCAACAGTTACATGGCACGGTAGTGAGAGAT
AATGGCAATTTGTTAAGTAGGTCTATGTTAAATTTTGTTAGATGGAGTTCCAAAGACAAT
GAGGACTTGGCGATGGACGAAACACAAATGGATTTTTCTGAATTGGATGAGTACATTATT
GGAAATTCATCATTCAAACAAGAATCGGTTAATATGGTAGGAATGGCGTGGGTGACGCCC
ACTTTTGAATTGTATCTGATTGGAAATAATGGGATTGTTGACAAAAGGGTTTTATTCAAG
AGTGCGAGAAAAGTAGCTAATTGGTGTCAAAAACACGAGTCGAGACTATTTATAAGTGAT
GGGGCCGTGTTTTAA
Promoter Sequence
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>MON1 YGL124C
TTTTCTTCAGTGTTTCTTGGTCCTCTTCTGTTTGGACGGCCTCTGTTACGGCCACCGAAA
CCACCTCTCTTTTGTTGTTGAGCTTCTGGAGCAGACATTACTTAATTAGTTGAGCTTATT
GGTTGTTTGTTATAGTCGGAATGGAACACGGAAAGTTGATGTAGGTAACTTTCAATCGAC
AATATATAAAGAACACGGTTTCTTTGGGATTGAAAAGGTATCAAGCAGTAAGGAAGGAAA
TTGGAAACAAAGGAAGAGAAAGTCTGAATTAAAAACTTGAAAACTCTTACGTTACTACAG
AGGGGAATAGATGAAAAAATAGCTAGGCGTCCTGGGAAGCTGCGTGCAATACTAAGGCAG
GACAGATACCTACGTTACCTCGTTAATGATGACATGCGTTTTCCATCAAATGTTTGCGTC
CAGTTCCATTATCACAAATCTTAAAATTCAAACAAGTAAATAATCCCATAGAGCGGGTGT
ATGGGTCTAGCTTAAATACACCCAACCATATTTAGAAAGCAGTCTTCTAAACCAAACAAT
CGCATGCCGACGTAGAAAACTATTAAGAAAACCTTAAGAATCCTTAGTGAATAAGCCAAT
TACTAAAATACGTGTAAACCTTCTTCGCGTCGAAAAGCAGTTCAAGCTCACATCCCGGAT
CTTTAATGAATATGGTTGGGCCCAATCAAAGATTTCCCGTCAAGTCTTTGCCAATGCTAA
ACAATAGTATCTTGCAATAGTGATCGTAAACCGTAACCTTATATTTACGTAGTAAGGCTA
GTATGCGTACCTTTATCCCTGATTAACAACATATCCTAATTCTTTTAGTCTTTCTTCTTA
TTTTGCTTACATAAAATGGTATTACTAGGCTCCATCGTTCTATCTCGTAGGGCTGAAATA
AAGGATAAAAACCGCGGTACGAGACAAAGATAGTAGTGAATACGAATTGAATAAAAAAGT
CTATCAAAGTACACAAACGTAGAATCAGTACATCGGAACT
Chr coordinates Chr VII from 276714-274780
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