Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Standard Name
PMR1
Systematic Name
YGL167C
Alias
BSD1, LDB1, SSC1
Strain
S288c
Description
High affinity Ca2+/Mn2+ P-type ATPase; required for Ca2+ and Mn2+ transport into Golgi; involved in Ca2+ dependent protein sorting, processing; D53A mutant (Mn2+ transporting) is rapamycin sensitive, Q783A mutant (Ca2+ transporting) is rapamycin resistant; Mn2+ transport into Golgi lumen required for rapamycin sensitivity; mutations in human homolog ATP2C1 cause acantholytic skin condition Hailey-Hailey disease; human ATP2C1 can complement yeast null mutant
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>PMR1 YGL167C
ATGAGTGACAATCCATTTAATGCGAGTCTTCTTGACGAGGACTCAAACCGTGAGAGAGAA
ATACTAGATGCCACAGCAGAGGCCCTTTCGAAACCAAGCCCTTCTTTAGAGTATTGTACT
TTATCCGTGGACGAAGCTCTAGAAAAACTGGACACTGACAAAAACGGTGGTTTACGATCA
TCTAACGAGGCCAACAATAGGAGATCACTTTATGGCCCCAATGAAATAACCGTAGAAGAT
GATGAAAGTCTTTTCAAGAAGTTCTTGTCAAATTTCATTGAGGATCGAATGATTCTACTT
TTAATAGGATCCGCAGTGGTCTCTCTTTTTATGGGTAACATTGATGATGCTGTTAGTATC
ACACTGGCCATTTTCATAGTTGTCACTGTCGGTTTTGTCCAAGAATATAGGTCTGAAAAA
TCTCTAGAAGCGTTGAATAAATTGGTTCCTGCTGAATGTCACTTAATGAGATGTGGTCAA
GAGAGTCATGTACTGGCTTCCACCTTGGTTCCTGGTGATTTAGTGCACTTCAGAATAGGT
GACAGAATCCCCGCAGACATTAGAATTATTGAAGCAATCGATTTATCCATCGATGAAAGT
AATTTAACTGGTGAAAATGAACCGGTACATAAAACCTCACAAACGATCGAAAAATCTTCC
TTTAACGATCAGCCTAATTCAATTGTACCGATTTCTGAGAGATCTTGTATAGCTTATATG
GGTACATTAGTCAAGGAAGGTCATGGTAAGGGTATCGTCGTAGGAACAGGTACAAACACA
TCCTTTGGTGCCGTTTTTGAAATGATGAATAATATTGAAAAACCGAAGACTCCATTGCAG
TTAACAATGGACAAATTGGGAAAGGACTTGTCACTGGTTAGCTTCATAGTTATTGGTATG
ATTTGTTTAGTTGGTATCATACAAGGTAGATCTTGGTTAGAAATGTTCCAAATATCGGTA
TCCTTAGCGGTTGCTGCTATTCCAGAAGGGTTACCAATTATTGTCACTGTTACTTTGGCA
TTGGGTGTTCTGAGAATGGCCAAGCGTAAAGCCATCGTGAGAAGGTTACCAAGTGTCGAA
ACTTTAGGCTCTGTCAACGTTATCTGCTCCGACAAAACAGGTACACTAACCTCAAACCAC
ATGACCGTATCTAAACTTTGGTGCTTGGACAGTATGTCCAATAAGCTAAACGTCCTCTCA
TTAGACAAAAATAAGAAGACTAAAAATTCTAATGGAAATTTGAAAAACTATTTGACTGAA
GACGTTAGGGAAACTCTAACTATCGGTAATCTCTGTAATAATGCATCTTTCTCTCAAGAA
CATGCCATATTTCTGGGAAATCCTACTGATGTAGCTCTTTTAGAGCAATTGGCAAACTTT
GAAATGCCTGATATCAGAAACACCGTTCAAAAAGTTCAGGAACTTCCATTTAACTCGAAA
AGAAAATTAATGGCAACCAAGATTCTCAACCCTGTCGACAATAAGTGTACAGTTTATGTT
AAAGGTGCATTTGAAAGAATTCTTGAGTACTCCACAAGTTATTTGAAATCAAAGGGTAAA
AAAACTGAAAAGTTGACTGAAGCCCAAAAAGCTACGATAAATGAGTGCGCAAATTCTATG
GCATCTGAAGGTTTGCGTGTCTTTGGATTTGCTAAACTAACTTTGTCTGATTCATCAACT
CCTCTAACCGAAGACCTAATCAAAGATTTAACCTTTACTGGTTTAATCGGTATGAATGAC
CCACCAAGACCGAACGTTAAATTTGCCATCGAACAATTACTACAAGGTGGTGTCCATATT
ATTATGATCACTGGTGATTCTGAGAATACCGCAGTAAACATTGCAAAACAAATTGGTATT
CCAGTTATTGATCCAAAGCTTTCCGTTTTATCCGGTGATAAATTAGATGAAATGTCAGAT
GATCAACTGGCCAATGTCATCGACCACGTTAATATTTTTGCTCGTGCTACGCCTGAGCAT
AAGTTAAACATTGTTCGTGCATTAAGAAAGAGGGGTGATGTGGTAGCAATGACTGGTGAT
GGTGTTAACGACGCTCCTGCGTTGAAACTTTCAGATATTGGTGTTTCTATGGGTAGAATT
GGTACAGATGTAGCCAAAGAAGCCTCAGATATGGTCTTAACTGATGATGACTTCAGTACT
ATTTTAACTGCCATTGAAGAGGGTAAAGGTATCTTTAATAATATTCAGAATTTCCTGACT
TTTCAATTGTCTACTTCTGTTGCCGCACTATCATTAGTTGCACTATCTACAGCGTTTAAA
CTACCCAATCCACTGAACGCAATGCAAATTCTTTGGATAAATATTTTAATGGATGGGCCA
CCAGCTCAATCCTTAGGTGTGGAACCTGTTGATCATGAAGTTATGAAAAAACCTCCAAGA
AAACGTACCGATAAAATTTTGACCCATGATGTAATGAAACGTTTACTAACCACCGCGGCC
TGTATCATCGTTGGGACAGTTTACATTTTTGTTAAAGAGATGGCCGAAGATGGTAAAGTA
ACTGCTAGAGATACTACTATGACATTTACTTGTTTTGTTTTTTTTGATATGTTTAATGCT
TTGGCCTGCAGACATAACACAAAGTCAATCTTCGAAATCGGCTTTTTCACGAACAAAATG
TTCAACTACGCCGTTGGACTGTCTCTGTTAGGTCAAATGTGCGCTATATATATACCATTT
TTCCAAAGTATCTTTAAAACTGAGAAACTTGGTATCTCTGATATACTATTGTTATTGCTC
ATCAGCAGTAGCGTTTTCATCGTTGATGAATTGAGAAAATTGTGGACGAGGAAAAAGAAT
GAAGAAGACTCAACGTATTTCTCAAATGTTTGA
Promoter Sequence
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>PMR1 YGL167C
CTGCTTCATCATTTGCCCTTCTGTGGCATGACCCTCCCTTTGATTTCCGGCTGCTTTTCC
TCTTGGTATGACATTTACAAGGTTCACCCTCATCACAACGACATCGTGTTTCATCTTCCT
TGCTGCCAACAGCTGGCCGTCGTGCAGAGGCACACATGCACCCACCGGATGGGTTGAAGT
TCTTGGTTCTTCTCAGCTCTTTACAATGGCCACATGTGGTCGATGGTCTTCCCTTGCGTC
TGATCATCTGTAGCGGACCATCAGTGTGAGTACACTGCGCCGCCCTGTGACCCCTGATAC
ACGTTTCACAGGCATATTTGACCCCGTTAATTACGACCATTCTGTGAATACACTGATTAT
CAGTCCTCTTTTATCAAGCCGCCGTCTAATAAATTACATCGCCATGGCTACTGCTATTTC
GTCCACAGCTTAATACTTACCGAACCAGGCCTTGCGGCTCTTACCCTGCGTGCCCGCGCA
CCCTGGCGACTTCGCCTCGTTTTGGCGATTTTCTTAGCAAATATTCTTTCACGATCGTAG
TGGTGGAAGGTGGGTGAAAAGAGTTGCGTTCCTAGCAAGGATCGGTTGGTATCAATTGCA
CGTTCAGCTCATCCCTAGATAACCACTTAACAGCAAAGCCGATCGTTAAACTTTTGTATT
CTACATTCTAGTTGCATTTTTTTTTTTTTTCATTTTGTTACATCAAGACAAGATTCTCTA
TTTAAAGAAGTACTTTTTTTGTTAACAGTGTGGACCCTACCTATCGTTATATCGAGATCT
TGTTCCCTAGGCCATCGTACACTATAGCCCTTCCTTCAAGCACTTAATAGAAAAACCTCT
TTTTCTACACCATCATAATAGTGTTTGCTCGCCCCGTTCTTTCCATTCCCATTTATAACA
ATACTAGTAACTATAATAATATCCTTACGACTGGGCAAGACAAGACGAAGCAAGGCCAGC
ACAGACGTAAGCTTAAGTGTAAGTAAAAGATAAGATAATT
Chr coordinates
Chr VII from 190468-187616