Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name XRN1
Systematic Name YGL173C
Alias DST2, KEM1, RAR5, SEP1, SKI1
Strain S288c
Description Evolutionarily-conserved 5'-3' exonuclease; component of cytoplasmic processing (P) bodies involved in mRNA decay; enters the nucleus and positively regulates transcription initiation and elongation; involved in microtubule-mediated processes, filamentous growth, ribosomal RNA maturation, telomere maintenance, and turnover of tRNA introns; negative regulator of autophagy; activated by the scavenger decapping enzyme Dcs1p; expression regulated by Ash1p in rich conditions
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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Promoter Sequence
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>XRN1 YGL173C
ACTATTATTGATATTATTAGTGTTATTATTACCAAACAAACCACGACTCGTCTGTGCATT
GTTGGAACCAAACAAACTGCCAGAATTACTGTTCGAATTAGCGCCAAATAACCCGCCCCC
AGTGTTCGCCGTATTGTTAGGTTTGTTACCGAAAAGGCCCCCTCCGGTGGTGGCGCTTCC
TCCAAATGCATTTGTCTGAGATTGTTGTTGCTGCTGACCAAATGATGCACCTAATCCTCC
TGTAGATCCGGCTGGTTTAGCGCCAAATAGTCCACCTGTACTTGGGCCGGTGTTTTGTCC
AGTTTGAGTCCCACCAAACGAAAACCCAGTATTCGCGTTTCCAGTGCTAGCTCCGCTGGC
CTGACCAAAGAGCCCACCTGCAGGTGTCGAAGATGCTTTATTTAATCCAAACATTGTGCC
CACTACCCGTGAAAACCCTCTCAATTACTGTTTTTATCGTCTCATCACCTGATCAGTAAC
TATTCTCACGATTAATGGTCTTTTTCAACTACATTTATTTGAGAAAGCTGTAATACATTC
CGTGTTGAGTGATATATACAACCTCCTTTGCTCGTCTTTTCGCCACCGCAGAGCAAGTAA
CAACAGAGACAAACAAGAAGAGGTTAGAAAGCAATTTAAGGAGTAGTTTAACGAGTACTG
AAAACGTCAAACTAAGTACTTACGACTTCCAATTACCGGTTGTAAAGTTTATCTACGCAA
ATATAACAGTTGCAGCTTGCTTTTTTTTTCAGCAGCTCTTCCGTTATTATAAAATCTGTT
TGGCGTTCGCACAAGCGAACCGATTCTTTTATTATTTTCTCTCTGCCTTTTATTTCCGTT
CCTGTTAATAGTTTATTTTCTAAAGGATACTGTCTTCTTCCGTACTTATAATCGGGTTCA
CAATAAGCAATTGACTAATCCTAGGACGATTCGTGTACTATAAGGAGAAAAAAAATCAAC
ACTTGTAACAACAGCAGCAACAAATATATATCAGTACGGT
Chr coordinates Chr VII from 180113-175527
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