Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
XRN1
Systematic Name
YGL173C
Alias
DST2, KEM1, RAR5, SEP1, SKI1
Strain
S288c
Description
Evolutionarily-conserved 5'-3' exonuclease; component of cytoplasmic processing (P) bodies involved in mRNA decay; enters the nucleus and positively regulates transcription initiation and elongation; involved in microtubule-mediated processes, filamentous growth, ribosomal RNA maturation, telomere maintenance, and turnover of tRNA introns; negative regulator of autophagy; activated by the scavenger decapping enzyme Dcs1p; expression regulated by Ash1p in rich conditions
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>XRN1 YGL173C
ATGGGTATTCCAAAATTTTTCAGGTACATCTCAGAAAGATGGCCCATGATTTTACAGCTT
ATTGAGGGAACACAGATTCCTGAGTTTGATAACTTATACCTGGATATGAATTCGATTTTA
CATAATTGTACGCATGGTAACGACGATGATGTAACCAAGCGATTAACTGAAGAAGAGGTT
TTTGCAAAAATCTGTACGTATATCGATCACCTTTTTCAAACAATCAAGCCCAAGAAGATT
TTCTACATGGCTATTGATGGTGTGGCCCCTCGTGCCAAGATGAATCAACAAAGAGCTCGT
AGATTCAGAACCGCTATGGATGCAGAAAAAGCCTTGAAGAAGGCTATTGAGAATGGTGAC
GAGATTCCTAAGGGTGAGCCATTTGATTCGAATTCTATTACTCCAGGTACGGAGTTTATG
GCCAAATTGACCAAAAACTTACAATATTTTATTCACGACAAGATTTCTAACGATTCCAAA
TGGAGGGAAGTGCAAATCATATTTTCTGGCCATGAAGTTCCAGGTGAAGGTGAACACAAG
ATCATGAACTTTATAAGGCATTTAAAATCCCAAAAGGATTTCAACCAGAATACGAGACAT
TGTATTTACGGTCTTGACGCAGATTTGATTATGCTGGGTTTGTCTACTCATGGGCCACAT
TTTGCGTTATTGAGAGAAGAAGTGACATTTGGTAGAAGAAATAGTGAAAAAAAATCGCTT
GAACATCAAAATTTCTACTTATTACATCTTTCTTTATTAAGAGAATACATGGAGTTGGAA
TTCAAAGAAATTGCCGATGAAATGCAATTTGAATACAATTTTGAACGTATTTTGGATGAT
TTTATTCTTGTCATGTTCGTCATTGGTAATGATTTCTTGCCCAATTTGCCAGATTTGCAC
CTTAACAAAGGAGCATTTCCCGTTTTGTTACAAACGTTCAAAGAAGCTCTTTTACATACT
GATGGCTACATTAATGAACATGGTAAAATAAATTTAAAGAGATTAGGTGTCTGGTTAAAT
TATCTGTCTCAATTTGAGTTATTAAATTTCGAAAAGGATGATATAGACGTTGAGTGGTTC
AACAAGCAATTAGAGAATATTTCTTTGGAGGGTGAAAGGAAAAGACAGAGGGTTGGTAAA
AAATTACTGGTAAAACAACAGAAGAAATTAATTGGAAGTATAAAACCATGGTTGATGGAG
CAATTACAGGAAAAATTATCGCCTGATTTACCAGATGAAGAAATTCCAACTTTAGAGTTA
CCTAAGGACTTAGACATGAAAGATCATTTAGAATTTTTAAAAGAATTCGCTTTTGATTTG
GGTCTTTTTATAACGCATTCCAAATCCAAAGGTAGTTATTCGCTAAAAATGGATCTTGAT
TCTATTAATCCTGATGAAACAGAAGAAGAATTTCAAAATCGTGTTAATTCTATCAGGAAA
ACAATAAAAAAATATCAAAATGCTATCATCGTGGAGGACAAAGAAGAATTGGAAACTGAA
AAAACGATTTATAATGAAAGGTTTGAACGTTGGAAGCATGAGTATTATCACGACAAGTTA
AAATTTACGACAGACAGTGAAGAAAAAGTGAGAGATCTTGCTAAAGACTACGTTGAAGGT
TTACAATGGGTTCTATATTATTATTATAGAGGATGTCCATCTTGGTCGTGGTACTATCCG
CACCATTATGCACCAAGAATCTCCGACTTAGCCAAGGGTTTAGATCAAGACATTGAATTT
GATTTGAGCAAACCATTTACTCCATTCCAGCAACTAATGGCAGTTTTACCGGAAAGGTCC
AAAAATCTGATACCTCCCGCCTTTAGGCCATTAATGTACGATGAACAGTCGCCAATCCAC
GATTTCTATCCCGCTGAGGTTCAACTTGATAAAAACGGCAAGACAGCTGATTGGGAAGCT
GTGGTTTTGATATCGTTTGTAGATGAAAAAAGGTTGATTGAGGCTATGCAACCTTATTTG
CGCAAGTTATCACCTGAAGAAAAAACGAGAAATCAATTTGGCAAGGACTTGATATATTCC
TTTAATCCTCAAGTTGATAACCTTTATAAGAGTCCGTTGGGCGGCATTTTTTCTGATATT
GAACACAATCATTGTGTCGAAAAAGAGTACATCACCATCCCATTGGACAGCTCCGAGATT
CGGTATGGTTTATTACCTAATGCTAAACTCGGTGCCGAAATGCTGGCGGGTTTCCCCACG
TTATTGTCTTTACCATTTACTAGTTCACTGGAGTACAATGAGACAATGGTTTTCCAACAA
CCTTCTAAACAACAATCAATGGTCTTACAAATAACTGACATATACAAAACGAATAATGTT
ACTTTGGAGGACTTTTCCAAGAGGCATTTAAACAAAGTGATTTATACAAGATGGCCATAT
TTAAGAGAATCCAAATTGGTCTCTTTAACGGATGGTAAGACTATCTATGAATATCAGGAG
TCCAATGATAAGAAAAAGTTCGGATTCATAACGAAGCCTGCGGAAACCCAGGACAAAAAA
CTTTTCAATAGTTTGAAGAATTCAATGCTAAGGATGTATGCTAAACAGAAAGCTGTTAAA
ATAGGACCTATGGAAGCCATTGCTACCGTCTTTCCAGTGACTGGTTTGGTGAGAGACTCT
GATGGTGGTTATATTAAGACCTTTAGCCCTACCCCAGATTACTATCCATTGCAACTGGTT
GTTGAATCTGTTGTCAACGAGGATGAAAGATATAAAGAAAGAGGACCCATTCCTATTGAA
GAGGAATTTCCATTGAATTCAAAAGTTATTTTCTTAGGTGATTATGCCTATGGTGGTGAA
ACTACTATTGACGGTTACAGCAGTGACCGCAGACTAAAAATTACTGTAGAAAAGAAGTTT
TTGGATAGTGAGCCCACCATCGGCAAAGAAAGGTTACAAATGGATCATCAAGCCGTTAAA
TATTATCCGTCTTATATTGTGTCCAAGAACATGCACTTACACCCCTTGTTTTTGTCTAAG
ATTACTTCCAAGTTCATGATTACTGACGCTACTGGGAAGCATATCAATGTTGGTATCCCG
GTTAAGTTCGAAGCTAGACACCAAAAGGTTTTAGGTTACGCGAGGAGGAACCCTAGGGGC
TGGGAATACTCAAATTTAACTCTAAATTTACTGAAAGAGTATAGACAAACTTTCCCAGAT
TTTTTTTTCAGGTTGTCCAAGGTAGGTAATGATATCCCAGTTTTGGAAGATCTTTTCCCC
GATACTTCCACTAAGGATGCCATGAATTTATTAGATGGTATCAAACAATGGCTAAAGTAT
GTCTCATCGAAGTTTATCGCGGTATCTTTGGAGTCTGACTCCTTAACTAAGACATCGATT
GCTGCCGTGGAAGATCATATCATGAAATACGCAGCTAACATCGAAGGTCATGAAAGAAAA
CAGTTAGCCAAAGTTCCTCGTGAGGCTGTTTTGAATCCAAGATCATCATTTGCACTCTTA
CGTAGTCAAAAGTTCGATTTGGGTGACCGTGTTGTTTATATCCAAGATTCTGGTAAGGTA
CCAATTTTCTCAAAGGGTACAGTTGTTGGCTATACTACTCTCAGTTCATCATTATCAATT
CAGGTCTTATTTGATCATGAAATCGTGGCCGGTAATAATTTTGGCGGCAGGTTGCGCACG
AATAGAGGCTTAGGGCTTGATGCCTCTTTCTTATTGAATATTACTAACAGGCAGTTCATT
TATCACTCCAAGGCTTCCAAAAAGGCTTTGGAAAAGAAAAAGCAATCTAACAATAGGAAC
AATAATACCAAAACTGCTCACAAGACTCCTTCAAAGCAACAATCTGAAGAAAAACTGAGA
AAAGAAAGGGCACATGATTTATTGAATTTTATCAAAAAGGATACCAATGAAAAGAATTCT
GAAAGTGTAGACAACAAGAGCATGGGATCGCAAAAAGATTCCAAACCCGCAAAGAAAGTT
TTGTTAAAAAGACCAGCTCAGAAAAGCAGTGAAAACGTGCAAGTTGATTTGGCCAATTTT
GAAAAAGCACCGCTTGATAATCCAACTGTTGCTGGATCTATTTTCAATGCCGTTGCAAAT
CAATATTCTGATGGTATAGGCAGTAATTTGAATATCCCAACTCCACCTCACCCAATGAAT
GTGGTTGGGGGTCCTATTCCTGGAGCGAATGATGTTGCAGATGTTGGTTTGCCGTACAAT
ATTCCCCCAGGTTTTATGACGCATCCTAATGGTCTTCACCCATTACACCCTCACCAGATG
CCTTACCCTAATATGAATGGAATGTCTATTCCGCCACCAGCACCACATGGGTTTGGACAA
CCGATTTCCTTCCCACCTCCACCTCCTATGACAAATGTTTCAGATCAAGGAAGTCGTATT
GTTGTCAATGAAAAGGAAAGCCAAGATTTGAAAAAATTCATTAATGGTAAACAGCACAGC
AATGGTTCAACTATTGGGGGAGAAACAAAGAACAGTAGGAAAGGCGAGATTAAACCTTCT
TCTGGCACAAACTCTACTGAATGTCAATCGCCAAAGTCACAAAGCAATGCTGCTGACCGT
GATAATAAAAAAGACGAATCTACTTAG
Promoter Sequence
Download FASTA
>XRN1 YGL173C
ACTATTATTGATATTATTAGTGTTATTATTACCAAACAAACCACGACTCGTCTGTGCATT
GTTGGAACCAAACAAACTGCCAGAATTACTGTTCGAATTAGCGCCAAATAACCCGCCCCC
AGTGTTCGCCGTATTGTTAGGTTTGTTACCGAAAAGGCCCCCTCCGGTGGTGGCGCTTCC
TCCAAATGCATTTGTCTGAGATTGTTGTTGCTGCTGACCAAATGATGCACCTAATCCTCC
TGTAGATCCGGCTGGTTTAGCGCCAAATAGTCCACCTGTACTTGGGCCGGTGTTTTGTCC
AGTTTGAGTCCCACCAAACGAAAACCCAGTATTCGCGTTTCCAGTGCTAGCTCCGCTGGC
CTGACCAAAGAGCCCACCTGCAGGTGTCGAAGATGCTTTATTTAATCCAAACATTGTGCC
CACTACCCGTGAAAACCCTCTCAATTACTGTTTTTATCGTCTCATCACCTGATCAGTAAC
TATTCTCACGATTAATGGTCTTTTTCAACTACATTTATTTGAGAAAGCTGTAATACATTC
CGTGTTGAGTGATATATACAACCTCCTTTGCTCGTCTTTTCGCCACCGCAGAGCAAGTAA
CAACAGAGACAAACAAGAAGAGGTTAGAAAGCAATTTAAGGAGTAGTTTAACGAGTACTG
AAAACGTCAAACTAAGTACTTACGACTTCCAATTACCGGTTGTAAAGTTTATCTACGCAA
ATATAACAGTTGCAGCTTGCTTTTTTTTTCAGCAGCTCTTCCGTTATTATAAAATCTGTT
TGGCGTTCGCACAAGCGAACCGATTCTTTTATTATTTTCTCTCTGCCTTTTATTTCCGTT
CCTGTTAATAGTTTATTTTCTAAAGGATACTGTCTTCTTCCGTACTTATAATCGGGTTCA
CAATAAGCAATTGACTAATCCTAGGACGATTCGTGTACTATAAGGAGAAAAAAAATCAAC
ACTTGTAACAACAGCAGCAACAAATATATATCAGTACGGT
Chr coordinates
Chr VII from 180113-175527