Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
IME4
Systematic Name
YGL192W
Alias
SPO8
Strain
S288c
Description
mRNA N6-adenosine methyltransferase essential for meiosis in S288C but dispensable for meiosis in SK1; mediates N6-adenosine methylation of bulk mRNA during the induction of sporulation which includes the meiotic regulators IME1, IME2 and IME4 itself; repressed in haploids via production of antisense IME4 transcripts; transcribed in diploid cells where antisense transcription is repressed; orthologous to human METTL3 (MT-A70)
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>IME4 YGL192W
ATGATTAACGATAAACTAGTACATTTTCTGATCCAGAATTATGATGACATCCTAAGAGCA
CCGCTTTCTGGACAGCTCAAAGATGTGTATTCACTGTACATCAGTGGCGGATACGATGAT
GAGATGCAGAAGTTGAGAAACGATAAAGACGAGGTCTTACAGTTTGAACAGTTTTGGAAT
GATCTTCAGGATATTATATTTGCAACGCCGCAGTCCATTCAATTTGACCAGAATCTATTA
GTGGCAGATAGGCCAGAAAAAATTGTTTACCTGGACGTTTTTTCCTTGAAAATTCTCTAT
AACAAGTTCCATGCCTTCTACTATACATTAAAATCGTCCAGTTCTTCATGTGAAGAAAAA
GTGTCGAGTTTAACAACAAAACCGGAAGCTGATTCGGAAAAAGACCAACTGCTGGGTAGA
CTGCTTGGAGTCCTGAACTGGGACGTTAACGTCAGCAACCAGGGGTTACCACGTGAACAA
CTGAGCAATCGCTTACAAAATTTATTGAGGGAAAAACCATCATCTTTTCAGCTTGCTAAA
GAAAGAGCCAAATACACGACCGAGGTCATTGAATACATCCCGATATGTAGTGACTATTCG
CATGCATCTCTATTGTCCACCTCGGTGTACATTGTCAATAACAAAATCGTTTCTTTACAA
TGGTCCAAAATATCCGCATGTCAGGAAAATCACCCAGGATTAATTGAGTGCATTCAATCA
AAAATTCACTTTATCCCTAATATCAAACCACAAACTGATATTTCGTTAGGAGATTGTTCC
TATTTGGATACCTGTCATAAATTAAATACGTGTCGATACATTCATTACCTGCAATATATT
CCGTCATGCTTGCAAGAGCGAGCTGATCGTGAAACTGCGAGTGAAAATAAAAGAATACGG
TCAAACGTTTCCATTCCATTTTATACTCTGGGCAATTGCTCCGCACATTGTATCAAAAAG
GCTTTACCTGCACAGTGGATCCGTTGCGATGTGCGGAAATTTGATTTTAGGGTTCTTGGA
AAGTTTTCGGTAGTTATTGCAGATCCTGCATGGAATATCCATATGAACCTACCATACGGT
ACTTGCAACGATATTGAACTATTAGGTTTGCCTTTGCACGAACTACAAGATGAAGGTATT
ATTTTTCTTTGGGTGACGGGTAGAGCTATAGAATTGGGTAAAGAGTCTTTGAATAACTGG
GGTTACAACGTGATAAATGAAGTTTCATGGATAAAGACAAACCAACTGGGTAGAACAATT
GTTACAGGTCGTACGGGTCATTGGTTAAATCATTCTAAGGAGCATTTATTGGTGGGCTTA
AAGGGTAATCCAAAGTGGATCAACAAACATATTGACGTCGATTTGATCGTATCAATGACC
AGAGAGACTAGTAGAAAGCCTGATGAACTGTATGGTATAGCAGAACGGTTGGCAGGCACC
CATGCCAGAAAACTAGAGATATTCGGAAGGGATCACAATACGCGGCCTGGCTGGTTTACC
ATCGGAAACCAGTTGACAGGAAATTGCATTTACGAAATGGATGTCGAGAGGAAGTACCAG
GAGTTTATGAAGAGCAAAACTGGAACCAGCCACACTGGTACTAAAAAAATCGACAAAAAG
CAACCTTCAAAATTACAGCAGCAGCATCAGCAGCAGTATTGGAATAATATGGATATGGGG
AGTGGTAAGTATTATGCTGAGGCCAAGCAGAATCCTATGAATCAAAAACATACTCCCTTT
GAATCCAAACAGCAACAAAAACAACAATTCCAAACACTAAATAACCTATATTTTGCTCAG
TAA
Promoter Sequence
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>IME4 YGL192W
TTGCATGATGAAGACCACCAGACCAATTTATCGCTATGTCCGATTGATTGTTGATTAGTT
TCCTGGTGGCGTCAAGGCTCGCACCAGTGTATAGTGTTGTATAATCATATAAATTTTGAA
AAATAGGACAGTCGTCTCCAATGTTAAAATTTTCAAGTGTGCCTCTGGGCAGTTTGTTTG
CATTTTCTGGTGAAACCTTCGAGAGAAAATTCACGTAGTCTTCCGAGTGAAATTGTAGTA
ATTCGTCTCTGGTAGCGCTTCTTGTTTCATAAAGGTCCATAATCTTGTGCAATCCATAAG
AGGAAACTAGGTGATCCGTTAGCATTAACCGAAACGGCTTCATTGGATGCTTAACACCAT
AATGGTAATGTGAAACTTTGGAGTTAAAATGATACGATACCCTGGGAGAATAAGCAGAAT
TAAACTCAAATAATGGTTCGTTCTCCTTTGTTTTCACATCATAACTAAATGTTCCAGACA
TGTTGCGTGTTGTTATTCACTTGATACCTGATTTTAACGTACTTGAGTAATCTGGCGTCT
TTTCTATAACTGTACATTGGCGACACACCTAAAACTGATTAGAATCGTTTCAAGATGCTT
TCAGTTCAACATTTAGTAACATAGTAGGAATATCACGTTTAACGATGCCCCAAAGAACAT
CGAGAATCCTCTATATAGAGTATAAACAGGGCATTCTACATTGGTATAGAGGTGCCTTAG
GTATATAGTGGTACCGGTCACATAAATTGACGGGAATATGCGTCTTTAGGCGGCTTTTGG
CGTACAGTATTGTTCTTTCTTTCGTGCTTGTGAAACTTGTTATAAACAAAGAAAGAGAAA
GATCTCCCCGGCATTCTGGAAGATCGGTAACCGCTGGAGCTATAGGAAAGGGAGATGGAT
AACAGTAAAGAAAACGGACCATATAAGTTAGCATTGGGGGTTTTCGAAAAAAATAAGAAT
TGGCATTCAGACTTGAATTCATAAAAGTTGTAAGCAGGCT
Chr coordinates
Chr VII from 142246-144048