Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name HXK2
Systematic Name YGL253W
Alias HEX1, HKB, SCI2
Strain S288c
Description Hexokinase isoenzyme 2; phosphorylates glucose in cytosol; predominant hexokinase during growth on glucose; represses expression of HXK1, GLK1, induces expression of its own gene; antiapoptotic; phosphorylation/dephosphorylation at Ser14 by kinase Snf1p, phosphatase Glc7p-Reg1p regulates nucleocytoplasmic shuttling of Hxk2p; functions downstream of Sit4p in control of cell cycle, mitochondrial function, oxidative stress resistance, chronological lifespan; has paralog HXK1
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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Promoter Sequence
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>HXK2 YGL253W
CCATTCCACAACTTTCATTTAGCACTACTGGGACAAGCAGTAGTGAAAGCGTTGATAGCA
CTACGGCACAAACCCCAACTGATCCAGAGAGTTACTGGTCGGATAACCGGTGCAAACATA
GTGATTGTCAAGAGCTTAGTCCATTCGCATCTGTATTTGATCTCATTGACCACTATGACC
ACACGCACGCCTTCATTCCTGAGACGCTGGTAAAGTACAGCTACATTCATTTATATAAGC
CTAGCGTCTGGGATTTATTCGAATACTGAACGCCATAGAAGAGCAATTTCCGTCCTCTAC
TCATGTGATTCGAACTATGAAACAAAGAAAAGGCAAGAGTAAATAGCGTGATACCTATTA
CGTATTACGTATACATCCTATTATTCTTGAAAAAAAGTGCGGGGCTCCAGAGCTCCACAT
TGGTGACCCCAGAGTATACTGCTCTTTCTAATGCCTTTTCCATCATGTTACTACGAGTTT
TCTGAACCTCCTCGCACATTGGTACCTAGAAATGGCTATCATGCCGGACGGCACCGGGCA
ATAAACCGGACGGCACAAAAAAATCGAAGAAAAGAGATTTCTTTTTCTCGCGGGCAGTTT
TTCCGGTCGATCGACATTCGTACGGTACTTTCTCTGTTTCAGGGACATCATGTTGTAAAA
GAAAAAGACAGTTTAGGTAATCGTTCTTTTCTTTCTGAAAAATTTTCCACGACGACGACG
ACGACCACGAAACACCTTTGATTGCGAGATCCACGAAATTACCTCCTGCTGAGGCGAGCT
TGCAAATATCGTGTCCAATTCCGTGATGTCTCTTTGTTGCACCTTCGCCACTGTCTTATC
TACAAAACTATAAAAAAGAGTAATCCTACCCCATATCTAAAAAAAATTCCTTAACTTTTA
TAACTTAACTTCAAAGTTTCTTAATATTTTTTCGCTTTTTCTTTGAAAAGGTTGTAGGAA
TATAATTCTCCACACATAATAAGTACGCTAATTAAATAAA
Chr coordinates Chr VII from 23935-25395
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