Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Standard Name
HXK2 Systematic Name
YGL253W Alias
HEX1, HKB, SCI2 Strain
S288c Description
Hexokinase isoenzyme 2; phosphorylates glucose in cytosol; predominant hexokinase during growth on glucose; represses expression of HXK1, GLK1, induces expression of its own gene; antiapoptotic; phosphorylation/dephosphorylation at Ser14 by kinase Snf1p, phosphatase Glc7p-Reg1p regulates nucleocytoplasmic shuttling of Hxk2p; functions downstream of Sit4p in control of cell cycle, mitochondrial function, oxidative stress resistance, chronological lifespan; has paralog HXK1 External sources
Open in SGD
Open in KEGG
Gene Sequence
Download FASTA Hide Seq
>HXK2 YGL253W
ATGGTTCATTTAGGTCCAAAAAAACCACAAGCCAGAAAGGGTTCCATGGCCGATGTGCCA
AAGGAATTGATGCAACAAATTGAGAATTTTGAAAAAATTTTCACTGTTCCAACTGAAACT
TTACAAGCCGTTACCAAGCACTTCATTTCCGAATTGGAAAAGGGTTTGTCCAAGAAGGGT
GGTAACATTCCAATGATTCCAGGTTGGGTTATGGATTTCCCAACTGGTAAGGAATCCGGT
GATTTCTTGGCCATTGATTTGGGTGGTACCAACTTGAGAGTTGTCTTAGTCAAGTTGGGC
GGTGACCGTACCTTTGACACCACTCAATCTAAGTACAGATTACCAGATGCTATGAGAACT
ACTCAAAATCCAGACGAATTGTGGGAATTTATTGCCGACTCTTTGAAAGCTTTTATTGAT
GAGCAATTCCCACAAGGTATCTCTGAGCCAATTCCATTGGGTTTCACCTTTTCTTTCCCA
GCTTCTCAAAACAAAATCAATGAAGGTATCTTGCAAAGATGGACTAAAGGTTTTGATATT
CCAAACATTGAAAACCACGATGTTGTTCCAATGTTGCAAAAGCAAATCACTAAGAGGAAT
ATCCCAATTGAAGTTGTTGCTTTGATAAACGACACTACCGGTACTTTGGTTGCTTCTTAC
TACACTGACCCAGAAACTAAGATGGGTGTTATCTTCGGTACTGGTGTCAATGGTGCTTAC
TACGATGTTTGTTCCGATATCGAAAAGCTACAAGGAAAACTATCTGATGACATTCCACCA
TCTGCTCCAATGGCCATCAACTGTGAATACGGTTCCTTCGATAATGAACATGTCGTTTTG
CCAAGAACTAAATACGATATCACCATTGATGAAGAATCTCCAAGACCAGGCCAACAAACC
TTTGAAAAAATGTCTTCTGGTTACTACTTAGGTGAAATTTTGCGTTTGGCCTTGATGGAC
ATGTACAAACAAGGTTTCATCTTCAAGAACCAAGACTTGTCTAAGTTCGACAAGCCTTTC
GTCATGGACACTTCTTACCCAGCCAGAATCGAGGAAGATCCATTCGAGAACCTAGAAGAT
ACCGATGACTTGTTCCAAAATGAGTTCGGTATCAACACTACTGTTCAAGAACGTAAATTG
ATCAGACGTTTATCTGAATTGATTGGTGCTAGAGCTGCTAGATTGTCCGTTTGTGGTATT
GCTGCTATCTGTCAAAAGAGAGGTTACAAGACCGGTCACATCGCTGCAGACGGTTCCGTT
TACAACAGATACCCAGGTTTCAAAGAAAAGGCTGCCAATGCTTTGAAGGACATTTACGGC
TGGACTCAAACCTCACTAGACGACTACCCAATCAAGATTGTTCCTGCTGAAGATGGTTCC
GGTGCTGGTGCCGCTGTTATTGCTGCTTTGGCCCAAAAAAGAATTGCTGAAGGTAAGTCC
GTTGGTATCATCGGTGCTTAA Promoter Sequence
Download FASTA
>HXK2 YGL253W
CCATTCCACAACTTTCATTTAGCACTACTGGGACAAGCAGTAGTGAAAGCGTTGATAGCA
CTACGGCACAAACCCCAACTGATCCAGAGAGTTACTGGTCGGATAACCGGTGCAAACATA
GTGATTGTCAAGAGCTTAGTCCATTCGCATCTGTATTTGATCTCATTGACCACTATGACC
ACACGCACGCCTTCATTCCTGAGACGCTGGTAAAGTACAGCTACATTCATTTATATAAGC
CTAGCGTCTGGGATTTATTCGAATACTGAACGCCATAGAAGAGCAATTTCCGTCCTCTAC
TCATGTGATTCGAACTATGAAACAAAGAAAAGGCAAGAGTAAATAGCGTGATACCTATTA
CGTATTACGTATACATCCTATTATTCTTGAAAAAAAGTGCGGGGCTCCAGAGCTCCACAT
TGGTGACCCCAGAGTATACTGCTCTTTCTAATGCCTTTTCCATCATGTTACTACGAGTTT
TCTGAACCTCCTCGCACATTGGTACCTAGAAATGGCTATCATGCCGGACGGCACCGGGCA
ATAAACCGGACGGCACAAAAAAATCGAAGAAAAGAGATTTCTTTTTCTCGCGGGCAGTTT
TTCCGGTCGATCGACATTCGTACGGTACTTTCTCTGTTTCAGGGACATCATGTTGTAAAA
GAAAAAGACAGTTTAGGTAATCGTTCTTTTCTTTCTGAAAAATTTTCCACGACGACGACG
ACGACCACGAAACACCTTTGATTGCGAGATCCACGAAATTACCTCCTGCTGAGGCGAGCT
TGCAAATATCGTGTCCAATTCCGTGATGTCTCTTTGTTGCACCTTCGCCACTGTCTTATC
TACAAAACTATAAAAAAGAGTAATCCTACCCCATATCTAAAAAAAATTCCTTAACTTTTA
TAACTTAACTTCAAAGTTTCTTAATATTTTTTCGCTTTTTCTTTGAAAAGGTTGTAGGAA
TATAATTCTCCACACATAATAAGTACGCTAATTAAATAAA
Chr coordinates
Chr VII from 23935-25395
