Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
COS12
Systematic Name
YGL263W
Strain
S288c
Description
Endosomal protein involved in turnover of plasma membrane proteins; member of the DUP380 subfamily of conserved, often subtelomeric COS genes; required for the multivesicular vesicle body sorting pathway that internalizes plasma membrane proteins for degradation; Cos proteins provide ubiquitin in trans for nonubiquitinated cargo proteins
External sources
Open in SGD
Open in KEGG
Gene Sequence
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Sequence hidden
Promoter Sequence
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>COS12 YGL263W
AGTCATTTGATCATACGCAGTTTTTCACTTCGAAATTTATAGCGCTAATTCTCTCCTATA
GGGGCATATATGAAGACAGTTAGACTGAACAAAAGAATTTAAATCTTGCGTATGTAGGTC
TTTAGAGTTTCACAGTTGATGTTTATCGCTGCAAATTTATATAAATCATCATACTGATAC
TGCTATAATATTTCCTTGTTCAATATTAAGTGATGGCTTTAAGATAGTCGTTTTTTACAG
AGCTTTAGGCAAGAATCTGAGTTTGAGCGTTACAAAGGTGGTTGCTTCAGGCATGTGCCT
GGGAAATGAACCTAATTGTATCTTTATATTTTTAAATAGTTATGAGGAGTGAGATGCATT
ATTATATTTATTATAGAGTGAATATTGAGGACTGCCTCGGATTTAACGCACCGCAAGCGT
ATATTCTACTATTTAATTATACCCACTTTTGTAATATAATTATTAATACAATATGTTTTT
ATTAAAGAGAGTGCAGAGAATCGAAAACCTAAAGAGTAGATTTGAAATCTAATAGTTTCA
CCTTAAAACACATCTCCTTTTAAAACTTATTGTAATTATTCATTAGAATTTTTATATTTA
ATTAATCTATCCTTTTTACTAATGAAAAATTCTTTAAATAAAAAAATCTATACATCCACT
AGAAAGTATATATAAATTTGGGGTACCTGCAATCTTTATTTATTTTATTTGAAGTAATAG
GAATTATTTATATTATTGTGATAAGAAGTAGTATTCTATTATTATAACTATATTAATAAA
AAATTTTATTTTCTATTGAAAACCAATTTTTTACACCAAATATCAGACACGCTTTGTCTA
TTTCTATCATATAGCGACTGTGATATAATGCGCGCGTGTTTTGAACGGCATTTTTTTAGC
CTGCGAATATGGATAGATGATGGTTTTAGGAAACATATGAACGAACTACCAGGACGTAAT
AACTGCAAAATAATGTCTCCTGAACTACATCGCCATAGGC
Chr coordinates
Chr VII from 2790-3932