Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name COS12
Systematic Name YGL263W
Strain S288c
Description Endosomal protein involved in turnover of plasma membrane proteins; member of the DUP380 subfamily of conserved, often subtelomeric COS genes; required for the multivesicular vesicle body sorting pathway that internalizes plasma membrane proteins for degradation; Cos proteins provide ubiquitin in trans for nonubiquitinated cargo proteins
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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>COS12 YGL263W
ATGGATGGAGCCAAATTTGAAAATACTGTAGCTTTTTTACCATCTGAAATATTTGATTGC
TACAATTCCACGCTACCCAAGAATGTATTCCGAAGTTTTGTTACCTGGTCCTGCTATGAG
AAATTCAATTCCTTAGAATTCCGCACTTGGCTATTAATGTGGTTACCACTCATTATTGCG
TGGAAAATACGTGGTAAAAGACACTATCTCGTTATCGTTACTGCTCTTATGTTTGAAGTG
CTGTATTTCTTATGGACATATTCGTACATATTCCGAGAACGCACCTTAGGAAAGCAAGTT
TCTCAATTTGCTAAAGAGATCATTACAAATACTCCGGGTATAGACACTGAAGACTGGGAA
CGTGTTGCAGTAAATTTCAATTCTTATTTATATGAAAATAAACTTTGGAATACTGAGTAC
TTTTTTTTTGATGGTTCCAGCTGCCAAGAAGCGTTCAGAAAGATGCTTCTTGAGCCATTT
TCCTTGAAAAAAAATGACTTTGCTAATGCCAAGGTACCTGACGGATCTGTTTGTTACACT
GAAAAAGCTTTGCAGGTTTATTTTACACAGATAGAGAGAAAATGGCACTGGATTAATTCT
GAAGGATTTTTACACAATAAAACCACACAGAGTGTTCAATTTTCGAAACATGGTTACGGT
TCCAAACTTCTCTGGGCTTTCAAGGAAGTGACAATAATGAATTCACGCTTTGCGTTCTTC
AGTATTGCTTACTTAAACGGTCTCCTTACTATACCAAGACTAAGAAATTCACTGCATATC
CTCTATGTATGTGCAGTTCTTTCATCTATGATAATTGAATATTTAATAGGGATCGACAAA
TTCAGGTTCAAATCAATGAATCTGATACATAAACTACAGTTCTTGTCATATATTACATGT
GGACACGAGAAGTCTGATGCAACTAATTGGTCTCAAATTGCGAAGAGGACGAATACTTAC
ATGTTTGAGCAGAAAATTTGGAATTCGCCAATACTGTTCTCAGATGGTATTGATTGTGAA
AAGTTTTTTAAATGGTATTTCAGTACCCCTGTATCTTCGCAAGCGTCTTTGTCAGTTGGT
TCCACTGATTTTGAACTCTGGCCATATATAAAAGAAGCACAATCAGCTTGCAATGATGTG
TAA
Promoter Sequence
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>COS12 YGL263W
AGTCATTTGATCATACGCAGTTTTTCACTTCGAAATTTATAGCGCTAATTCTCTCCTATA
GGGGCATATATGAAGACAGTTAGACTGAACAAAAGAATTTAAATCTTGCGTATGTAGGTC
TTTAGAGTTTCACAGTTGATGTTTATCGCTGCAAATTTATATAAATCATCATACTGATAC
TGCTATAATATTTCCTTGTTCAATATTAAGTGATGGCTTTAAGATAGTCGTTTTTTACAG
AGCTTTAGGCAAGAATCTGAGTTTGAGCGTTACAAAGGTGGTTGCTTCAGGCATGTGCCT
GGGAAATGAACCTAATTGTATCTTTATATTTTTAAATAGTTATGAGGAGTGAGATGCATT
ATTATATTTATTATAGAGTGAATATTGAGGACTGCCTCGGATTTAACGCACCGCAAGCGT
ATATTCTACTATTTAATTATACCCACTTTTGTAATATAATTATTAATACAATATGTTTTT
ATTAAAGAGAGTGCAGAGAATCGAAAACCTAAAGAGTAGATTTGAAATCTAATAGTTTCA
CCTTAAAACACATCTCCTTTTAAAACTTATTGTAATTATTCATTAGAATTTTTATATTTA
ATTAATCTATCCTTTTTACTAATGAAAAATTCTTTAAATAAAAAAATCTATACATCCACT
AGAAAGTATATATAAATTTGGGGTACCTGCAATCTTTATTTATTTTATTTGAAGTAATAG
GAATTATTTATATTATTGTGATAAGAAGTAGTATTCTATTATTATAACTATATTAATAAA
AAATTTTATTTTCTATTGAAAACCAATTTTTTACACCAAATATCAGACACGCTTTGTCTA
TTTCTATCATATAGCGACTGTGATATAATGCGCGCGTGTTTTGAACGGCATTTTTTTAGC
CTGCGAATATGGATAGATGATGGTTTTAGGAAACATATGAACGAACTACCAGGACGTAAT
AACTGCAAAATAATGTCTCCTGAACTACATCGCCATAGGC
Chr coordinates Chr VII from 2790-3932
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