Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Standard Name
ERG25
Systematic Name
YGR060W
Strain
S288c
Description
C-4 methyl sterol oxidase; catalyzes the first of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis; mutants accumulate the sterol intermediate 4,4-dimethylzymosterol; human MSMO1 functionally complements the growth defect caused by repression of ERG25 expression
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>ERG25 YGR060W
ATGTCTGCCGTTTTCAACAACGCTACCCTTTCAGGTCTAGTCCAAGCAAGCACCTACTCA
CAAACTTTGCAAAATGTCGCCCATTACCAACCTCAATTGAATTTCATGGAGAAATACTGG
GCCGCATGGTACAGTTACATGAACAATGATGTTTTGGCCACCGGTCTAATGTTCTTTTTA
TTGCATGAATTTATGTATTTCTTTAGATGTTTGCCATGGTTCATCATCGACCAAATTCCA
TACTTTAGAAGATGGAAGTTACAACCAACTAAGATTCCAAGTGCTAAGGAACAACTATAC
TGTTTGAAATCCGTTCTTCTATCTCATTTCTTGGTCGAGGCCATCCCTATCTGGACCTTC
CACCCAATGTGTGAAAAATTAGGTATTACTGTCGAAGTTCCATTCCCATCTTTGAAAACA
ATGGCTCTAGAAATTGGTCTATTCTTCGTCTTGGAAGATACATGGCATTACTGGGCTCAC
CGTCTATTCCACTACGGTGTCTTCTACAAGTACATTCACAAGCAACATCACAGATACGCT
GCTCCATTCGGTCTTTCTGCTGAATATGCTCATCCTGCTGAAACTTTGTCTTTGGGTTTT
GGTACCGTTGGTATGCCAATTCTTTACGTCATGTACACTGGTAAATTACACTTGTTCACT
CTATGTGTATGGATCACCCTAAGATTATTCCAAGCTGTTGACTCTCATTCTGGTTATGAC
TTCCCATGGTCTTTGAACAAGATCATGCCATTCTGGGCTGGCGCTGAACACCACGATTTG
CATCATCACTACTTTATTGGTAACTACGCTTCCTCTTTCAGATGGTGGGATTACTGTCTA
GACACTGAATCTGGTCCAGAAGCTAAGGCCTCCAGAGAAGAAAGAATGAAGAAGAGAGCT
GAAAACAATGCTCAAAAGAAGACTAACTAA
Promoter Sequence
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>ERG25 YGR060W
CCTTTCATCCGTCTCGTTTATCATAATGATGATTTCACTTATACCTATATGTTTTTTCTG
GCATCTCTAATGTTAGGATGTGAAGTTTAAGTACTCTCCATTCAATGAATACAATTTTTG
ACAATATCTGATTTTACTATGATTAAACAGACCGAGGGAGAAAAAAAAAAGGAACTAAAA
AAGGGCCTACGTAGAAGATGATGTAAAAGTAGATTCGCATCTGAGAATGTTTTCTTCAAA
TTTTTCTTTTCGGCCTTGGCGCAGAAGACTTTCTCTTCGTCCGCGTCGTATAGGAAACAA
AAAAGTGTAAAAAGTAAAAATCGGTATATTACGCAATCCATTCGTTACCCGGTGTAGTCA
CGTGCGGGTGCGGAGGGCAGCCGTTTAAACCCGTTTGGGCCTTGGTCCGATAGAACCATC
TCGCAGGAAAGAGCAGAGCCAGTTATCGGGTGTCGTTTACGCCCAGATGTCGTTTAGCCA
GCTCCGCAACGGCCACTGCCACTACCACTGCCTCCCTTCGTATACGGGACACAGAGATCG
TATACGGTAAACGACTAGCACTAGGACAATAGCAACTAACAATGACCGATAACAGTCAGC
AACCTCAAGGCACCTGGCACAAAACCGTCGAGGAAGAGGCCCTTTGCCACCGTATCGCAT
CGCTTTCCCACCAATTTTTTTTTTCTTGCTTGCCTCGCCTCTGCTGTGGTCGTATTATTA
TTATTCATTCTCTGCGCAGTTTAAACTATATACACACGATTAATCCGTTATGCATGTACA
TTTTCTTGTATGCGTACGCCTGTGTATGCATACTTCTATATAATATATAATACAGGAGGA
TCTATTCTTTTTTTTCTTCTTCTCTTCTTCTCTCCCTTTTTTCTCTCTCTTCGTTTCTTT
CCTTCCAGTAAATCTTTATATTAGTTGTAACTTTTTCTCTTTAGATAGTAGCATAGAGGA
CTAAGGAAAAGTAGTACAGCCATAAAAAAAAGAGGAAAAG
Chr coordinates
Chr VII from 610564-611493