Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name CYS4
Systematic Name YGR155W
Alias NHS5, STR4, VMA41
Strain S288c
Description Cystathionine beta-synthase; catalyzes synthesis of cystathionine from serine and homocysteine, the first committed step in cysteine biosynthesis; responsible for hydrogen sulfide generation; advances passage through START by promoting cell growth which requires catalytic activity, and reducing critical cell size independent of catalytic activity; mutations in human ortholog CBS cause homocystinuria; human CBS can complement yeast null mutant
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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>CYS4 YGR155W
ATGACTAAATCTGAGCAGCAAGCCGATTCAAGACATAACGTTATCGACTTAGTTGGTAAC
ACCCCATTGATCGCACTGAAAAAATTGCCTAAGGCTTTGGGTATCAAACCACAAATTTAT
GCTAAGCTGGAACTATACAATCCAGGTGGTTCCATCAAAGACAGAATTGCCAAGTCTATG
GTGGAAGAAGCTGAAGCTTCCGGTAGAATTCATCCTTCCAGATCTACTCTGATCGAACCT
ACTTCTGGTAACACCGGTATCGGTCTAGCTTTAATCGGCGCCATCAAAGGTTACAGAACT
ATCATCACCTTGCCGGAAAAAATGTCTAACGAGAAAGTTTCTGTCCTAAAGGCTCTGGGT
GCTGAAATCATCAGAACTCCAACTGCTGCTGCCTGGGATTCTCCAGAATCACATATTGGT
GTTGCTAAGAAGTTGGAAAAAGAGATTCCTGGTGCTGTTATACTTGACCAATATAACAAT
ATGATGAACCCAGAAGCTCATTACTTTGGTACTGGTCGCGAAATCCAAAGACAGCTAGAA
GACTTGAATTTATTTGATAATCTACGCGCTGTTGTTGCTGGTGCTGGTACTGGTGGGACT
ATTAGCGGTATTTCCAAGTACTTGAAAGAACAGAATGATAAGATCCAAATCGTTGGTGCT
GACCCATTCGGTTCAATTTTAGCCCAACCTGAAAACTTGAATAAGACTGATATCACTGAC
TACAAAGTTGAGGGTATTGGTTATGATTTTGTTCCTCAGGTTTTGGACAGAAAATTAATT
GATGTTTGGTATAAGACAGACGACAAGCCTTCTTTCAAATACGCCAGACAATTGATTTCT
AACGAAGGTGTCTTGGTGGGTGGTTCTTCCGGTTCTGCCTTCACTGCGGTTGTGAAATAC
TGTGAAGACCACCCTGAACTGACTGAAGATGATGTCATTGTTGCCATATTCCCAGATTCC
ATCAGGTCGTACCTAACCAAATTCGTCGATGACGAATGGTTGAAAAAGAACAATTTGTGG
GATGATGACGTGTTGGCCCGTTTTGACTCTTCAAAGCTGGAGGCTTCGACGACAAAATAC
GCTGATGTGTTTGGTAACGCTACTGTAAAGGATCTTCACTTGAAACCGGTTGTTTCCGTT
AAGGAAACCGCTAAGGTCACTGATGTTATCAAGATATTAAAAGACAATGGCTTTGACCAA
TTGCCTGTGTTGACTGAAGACGGCAAGTTGTCTGGTTTAGTTACTCTCTCTGAGCTTCTA
AGAAAACTATCAATCAATAATTCAAACAACGACAACACTATAAAGGGTAAATACTTGGAC
TTCAAGAAATTAAACAATTTCAATGATGTTTCCTCTTACAACGAAAATAAATCCGGTAAG
AAGAAGTTTATTAAATTCGATGAAAACTCAAAGCTATCTGACTTGAATCGTTTCTTTGAA
AAAAACTCATCTGCCGTTATCACTGATGGCTTGAAACCAATCCATATCGTTACTAAGATG
GATTTACTGAGCTACTTAGCATAA
Promoter Sequence
Download FASTA
>CYS4 YGR155W
AACAACCTTGCAGAGTCATTGTTCACATCACCTAACTCCTCAGATTCGTCTAATTTAGCT
GAAGCAATGCCACCAGTGGCAGTAAAGAATCTCTCTTTATATTTTTCCGGCCGGTGTGGA
GCAGGTAAGAAACGGGCACCCTTGGAGTCTAATTGCCAGTGAGATAACACAAGCCCTAGA
ACAGGTTCTAATTTCTTCAAAGACCTGGCAAGAATGGCTCTATGAGTGAATGGACACCCA
AGGGCCCCGTAAATATAATACCTTCCTTTTTCTGGTTTAAAAACAGAATGTGTCTTAGAA
ATTGTTCCCTTGTAAGATACTGACATGGCTTACTGTTTATGATTATTTTTACGAGTATTT
TCCTCTATAAGTGGCCATCTCTCCAATTGGCAAAGTCAAGACTTTTGTTATGTCAATATG
TGCTACCAAAAATCAAGGGTATTTTCCCACCAGAGCTTATCAATGGCAACTGTGAGATAT
GAACAGCAGTTAGTAAGGGTGTGTTCTCATCCGACCCTCTGATTCATTTGGTGGCCATTA
CATTTTCCCTCAATGACACATTCCCCTATTTCATAACTGATTAAAATGGTAATGGCACGT
GATAGTAGTGGCTCACAAAACAAAATTTTCTTTCTCAGCGCTGACAAAGCTTCATTTGCA
TTCTAACCTTATCACAACAACTTCAACTTCACCCAAGTAAGGATAATCAGCTCTGTCGTG
ACTGATAAATGCTATATCCGGCATATGCAGTCCACACGGCATTACCGTTTCACTAATTTA
TTGCCATCTTCCTCCACAGTTTTGCACCGAAAGGAAAAAAAGAAACCAACACCGAAAATT
TTTTTCTCCTAAAGGTTAAAGTAAACGCAAGGCACTTCACCAGGCTTGTATATATAAATG
TCGTGATGCTTCTATGCCAAAGTAAAAGGCAACACTTGAAGATTTCGTTGTAGGCCACTT
GCTCAAAGGACATCTAGATAAATACGACGTAAGAATAAAA
Chr coordinates Chr VII from 798543-800066
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