S.cerevisiae - Yeastract

Locus Information

Standard Name	UBR1
Systematic Name	YGR184C
Alias	PTR1
Strain	S288c
Description	E3 Ub-ligase (N-recognin); recognizes and ubiquitinates N-end rule pathway substrates in complex with Rad6p; Roq1p-bound form accelerates degradation of misfolded and native ER membrane and cytosolic proteins as part of the stress-induced homeostatically regulated protein degradation (SHRED) pathway; role in ER-associated protein degradation; modifies Cup9p to regulate peptide transport; mutation in human UBR1 causes Johansson-Blizzard Syndrome (JBS)
External sources	Open in SGD Open in KEGG

Gene Sequence Download FASTA Hide Seq	>UBR1 YGR184C ATGTCCGTTGCTGATGATGATTTAGGATCTTTACAAGGTCACATTAGGAGAACACTGAGG TCTATTCATAACCTCCCCTATTTTAGGTATACGAGAGGTCCTACTGAAAGGGCTGACATG AGCAGAGCCCTTAAAGAGTTCATTTACAGATATCTATACTTTGTCATTTCTAACAGCGGA GAGAACTTACCTACTTTATTCAATGCTCATCCAAAACAAAAATTATCTAACCCAGAGCTT ACTGTTTTTCCTGACAGTTTAGAAGATGCTGTGGATATTGATAAGATAACATCTCAACAA ACTATTCCGTTTTATAAGATAGATGAATCCAGAATAGGAGACGTCCATAAACATACCGGA AGAAATTGTGGGAGGAAATTCAAAATAGGGGAACCCTTGTATAGGTGTCATGAGTGTGGT TGCGATGATACTTGTGTGCTTTGTATTCATTGTTTTAATCCAAAAGATCATGTGAATCAT CATGTTTGTACCGATATATGTACTGAATTCACTAGTGGAATTTGTGACTGTGGAGATGAA GAAGCTTGGAATTCTCCACTTCATTGCAAAGCTGAAGAACAAGAAAACGATATATCGGAA GATCCCGCCACAAATGCCGACATAAAGGAAGAAGATGTATGGAATGATTCAGTGAATATA GCATTAGTGGAGTTGGTTCTTGCAGAAGTGTTTGACTATTTTATCGATGTTTTTAACCAG AATATCGAACCTCTACCCACAATACAGAAAGATATCACTATCAAATTAAGAGAGATGACA CAACAGGGAAAAATGTATGAAAGAGCGCAGTTTTTAAACGATTTAAAATATGAAAACGAT TATATGTTTGACGGAACAACAACAGCAAAGACGAGCCCCTCTAATAGCCCTGAGGCATCT CCATCGCTTGCGAAAATCGATCCCGAAAATTACACGGTAATAATATATAACGATGAATAT CATAACTATTCGCAGGCTACGACTGCCTTGAGACAGGGGGTTCCAGATAACGTACACATT GATCTATTAACATCCAGGATTGACGGAGAAGGTCGAGCAATGTTGAAATGTTCACAAGAT TTATCATCTGTCTTAGGTGGTTTTTTTGCTGTTCAAACGAATGGATTAAGTGCCACTTTA ACATCGTGGTCAGAATATCTTCATCAAGAAACATGCAAGTATATCATCCTTTGGATTACA CACTGTTTAAACATACCAAACTCCTCCTTCCAAACCACTTTTAGGAACATGATGGGTAAA ACCCTGTGTTCAGAATACTTAAATGCAACAGAATGTCGTGATATGACACCGGTGGTGGAG AAATATTTCAGCAACAAGTTCGATAAGAATGATCCCTACAGATACATCGATTTATCTATC CTTGCAGATGGCAATCAAATTCCTTTGGGTCATCACAAAATTCTACCCGAATCAAGCACC CATTCACTTTCACCATTGATAAATGATGTAGAAACTCCAACATCAAGAACATATTCTAAT ACAAGATTACAACATATTCTTTATTTTGATAACAGATATTGGAAAAGACTGAGAAAAGAT ATTCAGAATGTGATCATTCCAACGTTGGCCTCTTCAAATTTATACAAGCCCATTTTCTGT CAACAGGTAGTCGAAATATTCAACCACATCACAAGATCTGTGGCATATATGGATAGAGAA CCTCAGCTAACAGCTATAAGAGAGTGTGTCGTACAGTTATTTACATGCCCTACGAATGCC AAAAATATTTTCGAAAACCAAAGTTTTTTGGATATTGTGTGGTCAATTATAGACATTTTT AAGGAGTTTTGTAAGGTGGAAGGTGGTGTATTGATCTGGCAGAGAGTTCAAAAAAGCAAT TTAACAAAGAGTTACAGTATATCATTCAAGCAAGGGTTGTATACAGTTGAAACTTTATTG AGTAAGGTACATGATCCTAATATTCCATTGAGACCTAAGGAAATAATATCTCTATTAACT CTTTGCAAGCTCTTCAATGGAGCGTGGAAGATAAAGCGTAAAGAAGGTGAACATGTTCTT CACGAAGATCAAAATTTCATCTCCTATTTAGAATATACCACCTCCATTTACAGTATTATT CAAACAGCGGAAAAAGTTAGCGAAAAATCAAAAGATTCCATTGATTCAAAGCTTTTTTTA AATGCAATAAGAATTATCAGTTCATTTCTAGGCAATAGATCACTAACATACAAGTTAATA TATGATTCTCATGAAGTCATTAAGTTTAGCGTAAGCCACGAAAGAGTTGCATTTATGAAT CCTTTACAAACAATGCTTTCATTCCTTATCGAAAAAGTGTCTTTAAAGGATGCATACGAA GCGTTAGAAGACTGTTCAGATTTTCTGAAAATATCGGATTTCTCTTTGAGATCAGTTGTA TTGTGCTCTCAAATTGACGTCGGGTTTTGGGTAAGAAATGGTATGTCTGTGTTACATCAA GCATCGTATTATAAAAACAATCCCGAATTAGGTTCCTATTCCAGAGATATACATTTGAAT CAGTTAGCTATCCTTTGGGAACGTGATGACATTCCGAGAATAATATACAATATTCTTGAT AGATGGGAATTACTAGACTGGTTTACAGGTGAAGTTGACTATCAACACACTGTCTATGAG GATAAAATTTCATTCATCATTCAACAATTCATTGCCTTTATTTATCAAATATTGACCGAA AGACAATATTTTAAAACTTTCTCTTCTCTAAAGGATAGAAGAATGGATCAAATCAAAAAT TCAATCATTTATAACCTTTACATGAAACCCCTTTCGTATTCAAAGCTACTAAGATCAGTT CCTGACTACCTAACTGAAGATACTACCGAGTTTGACGAAGCACTTGAAGAAGTCTCTGTT TTCGTTGAGCCTAAGGGCTTGGCCGACAATGGTGTTTTTAAATTAAAAGCAAGCTTGTAT GCAAAGGTTGATCCGTTAAAGTTGCTGAATTTGGAAAACGAATTCGAAAGTAGTGCAACT ATTATTAAATCACATTTGGCTAAGGATAAGGATGAAATAGCAAAAGTTGTACTAATACCC CAAGTCTCAATAAAACAGTTAGATAAAGACGCTCTCAATCTGGGTGCTTTTACAAGGAAT ACGGTATTTGCCAAAGTGGTCTATAAACTACTCCAGGTATGTCTGGATATGGAGGATAGC ACTTTCCTGAATGAGCTACTACATTTAGTTCATGGTATATTCAGGGATGATGAATTGATA AATGGTAAGGACTCTATACCAGAAGCTTATTTGTCAAAGCCTATATGTAATTTACTCTTG AGCATAGCCAATGCTAAATCAGACGTATTTTCCGAGAGTATTGTCCGTAAAGCCGACTAT TTGTTAGAGAAGATGATAATGAAAAAACCAAATGAACTTTTTGAGTCATTAATTGCCAGT TTTGGCAACCAATACGTTAATGATTATAAGGATAAGAAACTACGCCAAGGAGTTAACTTA CAAGAGACAGAGAAGGAACGAAAAAGAAGATTGGCCAAGAAACATCAAGCAAGGCTTCTA GCCAAGTTTAACAATCAACAAACGAAATTCATGAAAGAACATGAGTCTGAATTTGATGAG CAGGATAACGATGTTGACATGGTCGGTGAAAAAGTATATGAATCGGAGGATTTTACCTGC GCACTATGTCAAGATTCCAGTTCGACCGATTTTTTTGTGATACCTGCGTACCATGATCAT TCCCCGATATTTAGACCTGGTAATATTTTTAACCCAAATGAATTTATGCCCATGTGGGAT GGTTTCTACAACGATGATGAAAAACAAGCTTATATTGACGATGATGTTTTAGAGGCTTTG AAGGAAAACGGTAGTTGTGGATCTAGGAAAGTATTTGTATCCTGTAATCATCACATTCAT CATAACTGCTTCAAGAGGTACGTTCAAAAAAAGAGATTTTCATCAAACGCGTTTATATGT CCTTTATGCCAAACATTTTCGAATTGTACTTTACCTCTTTGTCAAACCTCAAAGGCAAAT ACTGGTTTGTCGCTAGATATGTTTTTGGAATCAGAACTTTCTTTGGATACATTGTCAAGG CTCTTCAAACCTTTTACTGAGGAAAATTATCGTACAATAAACTCTATATTTTCGTTGATG ATATCTCAGTGTCAAGGTTTTGATAAAGCGGTAAGAAAGCGGGCCAACTTTTCGCATAAG GACGTTTCTTTAATATTAAGTGTGCACTGGGCAAATACCATTTCAATGTTAGAAATTGCT TCTAGGTTAGAAAAGCCATACAGTATTTCATTTTTCAGAAGCAGGGAACAGAAATACAAA ACTTTAAAAAATATATTAGTCTGCATTATGCTGTTCACCTTTGTCATAGGCAAGCCAAGT ATGGAGTTTGAACCGTACCCGCAGCAGCCCGATACTGTTTGGAACCAAAATCAACTCTTC CAATATATTGTTCGAAGCGCTTTATTTTCTCCAGTTTCACTTCGTCAGACTGTTACAGAG GCGTTAACAACGTTCTCTAGACAGTTTCTAAGAGATTTTCTTCAGGGTCTTTCTGATGCA GAACAGGTTACCAAATTGTATGCTAAAGCGTCCAAAATTGGGGATGTTCTTAAAGTAAGT GAGCAGATGCTCTTCGCCCTAAGGACCATATCTGATGTACGAATGGAGGGATTGGACTCC GAAAGTATTATTTATGATCTAGCTTATACCTTCCTGTTGAAGAGTCTTCTTCCTACGATA AGAAGGTGCTTAGTCTTTATCAAAGTGCTACACGAATTAGTGAAAGATTCTGAAAATGAA ACGCTGGTCATCAACGGTCATGAGGTTGAAGAAGAACTGGAATTCGAAGATACCGCCGAG TTTGTCAATAAGGCATTGAAAATGATTACTGAAAAAGAATCCTTAGTCGATCTTTTGACA ACGCAGGAGTCCATTGTATCGCATCCATATTTGGAGAACATCCCATATGAATATTGTGGG ATTATAAAACTGATAGATTTATCAAAATATTTGAATACTTACGTTACCCAATCTAAGGAA ATCAAGCTACGTGAAGAGCGTTCTCAGCATATGAAGAATGCGGATAATCGATTAGATTTC AAAATATGTTTGACATGTGGTGTCAAAGTGCATTTAAGAGCGGACCGCCATGAAATGACC AAGCATTTGAATAAAAATTGTTTTAAACCATTTGGCGCCTTCCTGATGCCCAATTCAAGT GAAGTTTGTCTCCATTTGACACAGCCTCCTTCTAATATTTTTATATCTGCACCATATCTA AATTCGCATGGTGAAGTTGGTAGAAATGCCATGAGAAGAGGTGATTTAACCACCTTGAAT TTGAAAAGATATGAGCACTTAAACAGATTATGGATTAACAATGAAATTCCAGGTTATATT AGTAGAGTAATGGGTGACGAATTTCGAGTGACTATACTTTCCAATGGTTTCTTGTTTGCA TTTAATAGAGAACCAAGGCCAAGAAGAATACCTCCAACAGATGAAGATGATGAAGATATG GAAGAGGGAGAAGACGGGTTTTTTACGGAGGGAAATGACGAAATGGATGTTGATGATGAA ACTGGACAGGCCGCCAACTTATTTGGGGTTGGCGCAGAAGGTATTGCTGGTGGCGGAGTA CGTGATTTTTTCCAATTCTTCGAAAACTTTAGGAACACTCTACAACCGCAGGGAAATGGC GATGATGATGCACCTCAGAATCCCCCACCAATATTGCAGTTCTTAGGACCTCAATTTGAT GGAGCTACTATCATAAGAAATACAAATCCAAGAAACCTCGATGAGGATGACTCTGATGAT AATGATGACTCTGATGAGCGAGAGATTTGGTAG
Promoter Sequence Download FASTA	>UBR1 YGR184C CCCCGGTAACGTCGAAGAGAATGGTTTACTGTCATTTGTCCAATATGTCATTGCACCAAT CCAAGAATTGAAGTTTGGTACAAATCACTTCGAATTCTTCATTGATAGACCAGAAAAGTT CGGTGGTCCAATTACCTACAAATCCTTCGAAGAAATGAAATTGGCTTTTAAAGAAGAAAA ATTGTCCCCACCTGATCTAAAAATTGGTGTTGCTGACGCTATCAACGAGCTATTGGAGCC AATCAGACAAGAATTTGCCAACAACAAGGAATTTCAAGAGGCCTCCGAAAAGGGTTATCC AGTTGCCACACCACAAAAGTCGAAAAAGGCTAAGAAACCAAAGAATAAGGGTACTAAGTA CCCAGGCGCTACTAAGACCAACGAGATTGCCACGAAACTAGAGGAAACCAAATTGTAAGC ATAGCTTAATCCGTTTTCACGATTCATAATATAATAAATAAGAAAAGATATATCATATAA ACGTTATAAAATTAATAACCGGGTAAGTGTAGAAAAGTGATGCGACGGTTTATTTTCTCT TCCTCTTGCGATTGAATTTAACTTGCAGATAGTGACCATAAGGCAACTACCCAGTGGCAA ACAGTTTTGATAACGCCCAGTACATCAACGAGCGAGTATAAAGACTTTGGTACATTTTAA AAAGGAAACATATATTGTTTTCATTGCTAGACCCTTTTAGTCTCACCTCAATAAAACTGC TTTATTCCTCATTGGGCTTTTTATTCTTTAATTTTGCATACTTATAGCGTGAAACTGGGC ATTTAACAAAAGCAAACTATTTTAATAGTAGCATCCTGCTTTCTTTGCCCCTCCTTCTTA TTGCGATACATTATTAAGTTTTTTTACCACCTTTCTTCCTTTTTCTTCGCATCTTCGGAC AAAGGCAGTTGAAGTTTACTGTATCCTATTAGTTGACTATTTTCTCTCACTGAAGTCCCT AATCTTTACAGGTCACACAAATTACATAGAACATTCCAAT
Chr coordinates	Chr VII from 865753-859901