Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
BUB1
Systematic Name
YGR188C
Strain
S288c
Description
Protein kinase involved in the cell cycle checkpoint into anaphase; in complex with Mad1p and Bub3p, prevents progression into anaphase in presence of spindle damage; Cdc28p-mediated phosphorylation at Bub1p-T566 is important for degradation in anaphase and adaptation of checkpoint to prolonged mitotic arrest; associates with centromere DNA via Skp1p; involved in Sgo1p relocalization in response to sister kinetochore tension; paralog MAD3 arose from whole genome duplication
External sources
Open in SGD
Open in KEGG
Gene Sequence
Download FASTA
Hide Seq
>BUB1 YGR188C
ATGAATTTAGATTTAGGTTCTACTGTACGAGGCTATGAATCAGATAAAGACACATTTCCG
CAATCGAAAGGCGTTAGCTCATCTCAAAAAGAGCAGCATAGTCAACTGAATCAGACAAAA
ATAGCTTATGAACAGAGACTTCTAAATGATTTAGAGGATATGGATGATCCTTTAGATTTG
TTTTTAGATTATATGATATGGATTAGCACCAGCTATATTGAAGTAGATTCTGAATCAGGT
CAAGAAGTTCTCCGAAGTACAATGGAAAGATGCTTGATTTACATACAAGATATGGAAACC
TATAGGAACGATCCCAGATTTTTAAAAATTTGGATTTGGTATATAAATTTGTTTCTTAGC
AACAACTTCCACGAGAGTGAAAATACTTTTAAATATATGTTTAACAAGGGAATCGGAACA
AAGCTTTCGTTATTTTATGAAGAGTTCTCCAAGCTACTAGAAAATGCTCAATTTTTTCTA
GAAGCAAAGGTGTTATTAGAACTAGGGGCTGAAAACAATTGCAGGCCTTACAACAGACTA
TTAAGGTCATTAAGCAATTATGAAGACAGACTCCGAGAAATGAACATCGTAGAAAACCAG
AACAGTGTACCTGATTCAAGGGAAAGATTGAAGGGAAGGTTAATTTATAGAACAGCACCA
TTTTTCATTCGTAAATTTTTAACCTCATCATTGATGACTGATGACAAGGAAAATCGTGCG
AACCTGAACTCTAATGTTGGAGTTGGTAAGTCTGCTCCTAACGTATATCAAGATTCTATA
GTGGTTGCTGACTTTAAGTCAGAAACAGAGAGGCTTAATTTGAATAGCTCTAAACAGCCC
TCTAACCAACGCTTGAAGAATGGAAATAAAAAAACTTCAATATATGCAGATCAAAAGCAA
TCTAACAATCCAGTCTACAAACTAATCAATACTCCGGGACGGAAACCTGAACGGATAGTT
TTTAATTTTAATCTAATATATCCAGAAAATGATGAGGAGTTCAACACCGAAGAAATATTG
GCAATGATTAAGGGACTTTACAAGGTACAGCGCAGAGGTAAGAAGCACACCGAAGATTAT
ACAAGTGACAAAAATAGGAAGAAACGTAAGCTCGATGTGCTGGTAGAGAGACGGCAAGAC
TTACCTTCATCACAGCCACCCGTTGTCCCCAAATCTACGCGAATTGAGGTGTTTAAAGAT
GACGATAATCCCAGCCAGAGCACACACCATAAAAATACACAGGTACAAGTGCAAACGACA
ACGTCTATTTTACCTTTGAAGCCTGTGGTTGATGGAAACCTCGCGCATGAGACACCAGTG
AAGCCCTCACTAACATCCAACGCTTCCCGTTCACCTACAGTAACAGCTTTTTCAAAAGAC
GCTATAAATGAGGTCTTTTCCATGTTCAATCAACATTATTCAACCCCGGGTGCGCTATTA
GATGGTGATGATACCACTACAAGTAAATTCAACGTCTTCGAAAATTTTACCCAAGAATTT
ACAGCAAAGAATATTGAAGATTTAACTGAAGTTAAAGATCCTAAACAAGAGACGGTGTCA
CAACAAACTACCTCAACAAATGAAACCAACGATCGATATGAAAGATTGTCGAATAGTAGC
ACACGGCCAGAAAAGGCAGACTACATGACGCCTATAAAAGAAACTACTGAAACAGATGTG
GTACCTATAATCCAGACACCTAAGGAACAAATAAGGACAGAAGATAAGAAATCGGGGGAT
AATACAGAAACACAAACTCAATTAACAAGCACAACCATTCAAAGTTCTCCATTTCTCACA
CAACCTGAACCACAAGCAGAAAAGCTTTTACAAACTGCAGAACATTCGGAAAAGAGTAAA
GAGCATTACCCAACGATCATACCTCCCTTCACTAAAATAAAAAATCAACCGCCTGTCATT
ATTGAAAACCCACTTAGTAATAATTTAAGAGCGAAGTTTTTATCCGAAATTTCGCCCCCA
TTATTCCAATATAACACCTTTTATAACTACAACCAAGAATTGAAAATGAGTTCTCTATTG
AAAAAAATCCATAGGGTATCCCGCAACGAAAACAAGAACCCAATTGTTGACTTCAAGAAG
ACGGGTGATTTATATTGTATACGCGGAGAATTAGGCGAAGGAGGTTATGCCACTGTATAT
CTAGCAGAATCTAGTCAAGGACATCTGCGAGCGTTGAAAGTAGAAAAACCTGCAAGTGTA
TGGGAATATTACATAATGAGCCAAGTGGAGTTTAGGTTGAGGAAGAGCACAATATTAAAG
TCAATAATCAACGCTAGTGCTTTACACTTGTTCCTTGATGAGAGCTACCTTGTTTTAAAC
TACGCCAGTCAAGGTACGGTCTTGGATTTAATTAATTTACAACGGGAAAAGGCAATTGAC
GGCAACGGAATAATGGATGAATATTTGTGCATGTTTATCACTGTCGAGCTAATGAAAGTA
CTTGAAAAGATACATGAAGTGGGAATAATACATGGCGATTTGAAACCAGATAACTGCATG
ATCAGATTAGAAAAACCAGGCGAACCCCTGGGTGCTCATTATATGCGCAATGGAGAGGAT
GGCTGGGAAAACAAGGGAATCTATTTAATAGATTTCGGTAGATCATTTGATATGACACTG
TTACCACCTGGAACGAAATTCAAATCAAATTGGAAGGCTGATCAGCAAGATTGCTGGGAA
ATGCGTGCGGGCAAGCCATGGAGTTATGAAGCGGATTATTATGGATTAGCAGGCGTCATA
CATTCGATGCTTTTTGGAAAATTCATAGAAACAATCCAGCTGCAGAATGGACGATGCAAA
TTGAAGAACCCATTCAAAAGGTATTGGAAAAAAGAAATATGGGGCGTTATATTTGATTTA
CTGTTAAATAGCGGTCAAGCTTCCAATCAAGCTTTGCCGATGACTGAAAAGATTGTTGAA
ATAAGGAATTTGATAGAAAGCCATCTGGAACAGCACGCAGAAAATCACTTAAGAAACGTA
ATTCTAAGCATTGAAGAGGAGTTATCACATTTTCAATATAAGGGGAAACCGTCAAGGAGA
TTTTAG
Promoter Sequence
Download FASTA
>BUB1 YGR188C
TATGTTTCATTATTACATTATCAATCCTCGCATTTCAGCTTCCTCTAACTTCAATGACCG
CTTCTCATAACTTATGCCATCATCTAACACCGTATATGATAATATATTAGTAAAACGAAT
ACTACTAAATAAAAGATAATTTAGAGTTTCATTCCAACAATAGATGATAGTTGTAGTCCT
TATTCTAACAGTTTATAATTCTCGAAGAAAACTTCTATTACATTTATGCCACAGTTACCC
TTTCTAATAGGAAACTAAGTTCCATAAATTGTCATCAAGTTCTAACGCTGCCAAGATAGA
AAACCATCAAACGTTAAAATATAAAGTGCGGTTGGATAAAAACTAGAGACATCGACGCTG
TACGAAGAAAATATCGAAAGCTATCTCAAGGAACATAAAAATCCAATTCTGTAACAATTA
TATGCTGAATAGGTAAATTACAAAATAGAATTGTTAGATTTCGTTCTTAGCGAAGACAAT
AATGATATATAACATATATCAAAACATTCTCCTTTTGAGGTATTGAAAACATGCAAGTAG
AAAGGCAATTGAACGTTTTATGTAATGGTTTCTTATCTTGATTTTATACGTCACCTCTCA
TTAATCCTTTTATCCCCCCAATTCTCATGGTTCAGTTTCCATTGAATCTGATGACAGTTG
AGTTTTATTCTACCGACTCCATAACTTGTGCCAACTTTTAAAATAGTTCAAGGTAATGTC
TTAATGAATTCTCTACTAATTAATGCTCAATAGCTGGTTTTTATTTTAGGAGTGTGTTTA
ACGTTTGACTTCACGTCCATGGGGTCATCTTGTAACGGACACGGTTTTTTTGGTCTTTCA
TTGTTTTCGCTTTCGATACGCGCTAGGAAGTAAATAAAGAAAAAAAAGCGTTGTTCATAT
ACATACACAATATACGTGATTTTAGAATAGAGTATAAAGTTTTCATCATGGAAAGATTAT
TGACGGTTCCTATTGTTTGAATGTTAACGCTGACCAGGAA
Chr coordinates
Chr VII from 875109-872044