Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name MES1
Systematic Name YGR264C
Alias MESI, MetRS
Strain S288c
Description Methionyl-tRNA synthetase; forms a complex with Gus1p, a glutamyl-tRNA synthetase, and Arc1p, which increases the catalytic efficiency of both synthetases; involved in the nuclear export of tRNAs; mutations in human ortholog MARS is associated with pediatric pulmonary alveolar proteinosis, interstitial lung and liver disease, and Charcot-Marie-Tooth disease; human MARS gene can complement the yeast null mutant
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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Promoter Sequence
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>MES1 YGR264C
CTCGCCTCTAACTACCACCATAATAGACCCCTCGTAGGTTTTTTCCTTAAAATCCATGTT
GATGAGTCTTAATATCGGTCCACATATAATACCAGACTTTGGAATTGGCGAAGTTTCGGA
ACAGTCATCGCAGCCAGTGACATCGTCTCTATAAAGAGCTTCTGGGTTCCAATCGTCGAA
CCAGTTTGTAGCATGCATTTTTGTAGCAGTGTTTATTTTCAATTGAGTACTTTGAACCCG
GTAGCAACTGTTTTGACCTTCTGTAGGACTTTCCCCTCACTAACTTTGTGGAATTTCTTT
TCATTTTTACTAATGGACCCTTCGCTATGTAGCCGTGCCGATAAAAATATATTCCTGGTA
TTACCCGACGCTGCTATTTCAACTTTTTTCAATAAAAGGACGAAAAAATAACATGTTTAA
TCTTGAGACCTTCTGGGTTAAGTTTATTGATAGAGATTAAGTACTAGTTTAAAACGTCTC
AGGCATAAAACATGAATTATGCTAACTTTTTAGCTACAGCGGACATAGTTGTACAAACTG
AGGAAAGGCTTCTTTAACCAGGGATTTTGAAGTAGGAATTGTTGAAGTCAAAAATGGGAA
CCTATGGAGGGGAATTCAAAAGGCATGAAGTCAAAAGATTAACATAATATAATTCAACTT
TGAAAAATATTCTAGTCAAAGCTTTCCCGAGAACGCGTAGCGTGATGATAATGGTGTATC
CTATCGATCTGTCGACTTGCTATGATTATCTTTGTTAGCCGCCGAAACGATCATTTATGC
ATTGCCCGAGTATAGTCACTTCTTCTCAATATCACGAGGCACGAATGATTTCGGAGGCAG
AAAAAATTTCTGTACGCAACTTATCGAAAGAGAAAACGAAAAAAAAAAAAAGACGATGAC
AAATTTTCTTCGATGTCTAATGTTAATGATGATTTGCTTCCTGATATGCATCTTTGTGGA
GGAATAAAACTTGAAAAAAAAGCGGAAATTTACAACAAGC
Chr coordinates Chr VII from 1021853-1019598
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