Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Standard Name
MES1
Systematic Name
YGR264C
Alias
MESI, MetRS
Strain
S288c
Description
Methionyl-tRNA synthetase; forms a complex with Gus1p, a glutamyl-tRNA synthetase, and Arc1p, which increases the catalytic efficiency of both synthetases; involved in the nuclear export of tRNAs; mutations in human ortholog MARS is associated with pediatric pulmonary alveolar proteinosis, interstitial lung and liver disease, and Charcot-Marie-Tooth disease; human MARS gene can complement the yeast null mutant
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>MES1 YGR264C
ATGTCTTTCCTCATTTCCTTTGATAAATCGAAGAAACATCCTGCCCATTTGCAGTTAGCG
AACAATTTGAAGATTGCCCTAGCACTTGAATATGCAAGCAAAAATTTAAAGCCTGAAGTT
GACAATGATAATGCTGCCATGGAATTGCGCAATACAAAGGAACCTTTCCTTTTGTTTGAT
GCTAACGCTATTCTAAGATATGTCATGGATGATTTTGAAGGTCAAACTTCCGACAAGTAT
CAATTTGCATTGGCATCTTTACAAAACCTGTTATATCATAAAGAATTACCTCAACAACAT
GTCGAGGTTTTGACAAATAAGGCCATTGAAAATTACTTGGTCGAATTAAAAGAACCATTG
ACTACTACAGATTTGATCCTGTTTGCTAACGTTTATGCTCTAAATTCTTCTTTAGTTCAT
TCTAAATTCCCAGAATTGCCATCCAAAGTGCATAACGCTGTAGCATTGGCTAAAAAGCAT
GTTCCACGTGATTCTTCTTCTTTCAAAAACATCGGCGCAGTGAAAATCCAAGCTGACTTA
ACAGTTAAGCCAAAGGATTCAGAAATTTTGCCTAAGCCAAACGAAAGAAACATCTTGATC
ACTTCGGCATTACCTTATGTCAACAACGTTCCACACTTGGGTAATATCATCGGTAGTGTT
CTTTCAGCAGACATTTTTGCTCGTTACTGTAAGGGACGTAATTATAATGCCTTGTTTATT
TGTGGTACTGATGAATATGGTACTGCCACGGAAACTAAAGCTTTGGAGGAAGGTGTGACA
CCAAGACAATTATGTGACAAATATCACAAAATCCACAGTGACGTTTACAAGTGGTTCCAA
ATTGGATTTGATTATTTCGGTAGAACTACGACGGACAAGCAAACGGAGATTGCTCAACAT
ATTTTTACAAAGCTAAATTCGAATGGTTATCTAGAAGAACAATCTATGAAGCAATTGTAC
TGTCCAGTTCATAATTCTTATCTGGCTGATCGTTACGTGGAAGGTGAATGTCCAAAATGT
CACTACGATGATGCTCGTGGGGATCAATGTGACAAATGTGGTGCCCTGTTAGATCCATTT
GAATTGATCAATCCACGTTGTAAATTAGATGATGCTTCTCCAGAACCAAAATATTCTGAT
CATATTTTCCTATCGCTGGATAAATTAGAAAGCCAAATTTCTGAATGGGTTGAAAAGGCC
TCTGAAGAAGGTAACTGGTCAAAAAATTCAAAAACAATTACGCAATCATGGTTGAAGGAT
GGTTTGAAGCCACGTTGTATTACAAGAGATTTAGTTTGGGGTACGCCAGTGCCTTTAGAA
AAATATAAAGACAAAGTCTTGTACGTTTGGTTTGACGCTACAATCGGCTACGTTTCCATC
ACTTCCAACTACACCAAAGAATGGAAACAATGGTGGAATAATCCAGAGCATGTTTCATTG
TATCAATTCATGGGTAAGGACAATGTTCCTTTCCATACAGTTGTTTTCCCTGGTTCTCAA
TTGGGTACGGAAGAGAACTGGACTATGTTGCACCATTTGAATACTACAGAATACTTACAA
TATGAGAACGGTAAATTTTCTAAAAGTAGGGGTGTTGGTGTTTTTGGTAATAACGCTCAA
GACTCTGGAATTTCTCCAAGTGTTTGGAGATACTACCTGGCATCTGTTAGACCAGAATCT
AGTGATTCTCATTTCTCATGGGATGACTTTGTTGCTAGAAACAACAGTGAATTGTTGGCT
AACTTGGGTAACTTTGTTAACAGATTAATTAAGTTTGTTAATGCCAAATATAATGGTGTT
GTTCCAAAATTCGACCCCAAGAAGGTTTCCAATTATGATGGTTTAGTTAAAGATATCAAC
GAAATTTTATCAAATTACGTCAAGGAAATGGAACTTGGACATGAAAGACGTGGTCTAGAA
ATTGCCATGTCGTTAAGTGCTCGTGGTAACCAGTTTTTGCAAGAAAATAAGTTGGACAAT
ACCTTGTTTTCACAGTCCCCAGAAAAGTCAGATGCTGTTGTCGCAGTTGGTTTGAATATT
ATTTACGCTGTTAGCTCTATTATCACACCATATATGCCAGAAATAGGTGAGAAAATAAAC
AAGATGTTAAATGCACCAGCTTTAAAAATTGATGATAGATTCCATTTGGCAATCCTAGAA
GGACATAATATAAACAAGGCAGAATACTTGTTCCAACGTATTGATGAAAAGAAAATCGAT
GAATGGAGAGCCAAATATGGTGGTCAACAAGTGTAA
Promoter Sequence
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>MES1 YGR264C
CTCGCCTCTAACTACCACCATAATAGACCCCTCGTAGGTTTTTTCCTTAAAATCCATGTT
GATGAGTCTTAATATCGGTCCACATATAATACCAGACTTTGGAATTGGCGAAGTTTCGGA
ACAGTCATCGCAGCCAGTGACATCGTCTCTATAAAGAGCTTCTGGGTTCCAATCGTCGAA
CCAGTTTGTAGCATGCATTTTTGTAGCAGTGTTTATTTTCAATTGAGTACTTTGAACCCG
GTAGCAACTGTTTTGACCTTCTGTAGGACTTTCCCCTCACTAACTTTGTGGAATTTCTTT
TCATTTTTACTAATGGACCCTTCGCTATGTAGCCGTGCCGATAAAAATATATTCCTGGTA
TTACCCGACGCTGCTATTTCAACTTTTTTCAATAAAAGGACGAAAAAATAACATGTTTAA
TCTTGAGACCTTCTGGGTTAAGTTTATTGATAGAGATTAAGTACTAGTTTAAAACGTCTC
AGGCATAAAACATGAATTATGCTAACTTTTTAGCTACAGCGGACATAGTTGTACAAACTG
AGGAAAGGCTTCTTTAACCAGGGATTTTGAAGTAGGAATTGTTGAAGTCAAAAATGGGAA
CCTATGGAGGGGAATTCAAAAGGCATGAAGTCAAAAGATTAACATAATATAATTCAACTT
TGAAAAATATTCTAGTCAAAGCTTTCCCGAGAACGCGTAGCGTGATGATAATGGTGTATC
CTATCGATCTGTCGACTTGCTATGATTATCTTTGTTAGCCGCCGAAACGATCATTTATGC
ATTGCCCGAGTATAGTCACTTCTTCTCAATATCACGAGGCACGAATGATTTCGGAGGCAG
AAAAAATTTCTGTACGCAACTTATCGAAAGAGAAAACGAAAAAAAAAAAAAGACGATGAC
AAATTTTCTTCGATGTCTAATGTTAATGATGATTTGCTTCCTGATATGCATCTTTGTGGA
GGAATAAAACTTGAAAAAAAAGCGGAAATTTACAACAAGC
Chr coordinates
Chr VII from 1021853-1019598