Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Standard Name
LAG1 Systematic Name
YHL003C Strain
S288c Description
Ceramide synthase component; involved in synthesis of ceramide from C26(acyl)-coenzyme A and dihydrosphingosine or phytosphingosine, functionally equivalent to Lac1p; forms ER foci upon DNA replication stress; homolog of human CERS2, a tumor metastasis suppressor gene whose silencing enhances invasion/metastasis of prostate cancer cells; LAG1 has a paralog, LAC1, that arose from the whole genome duplication External sources
Open in SGD
Open in KEGG
Gene Sequence
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>LAG1 YHL003C
ATGACATCAGCTACGGACAAATCTATCGATAGGTTAGTTGTTAATGCAAAAACAAGAAGA
CGAAACTCTTCCGTGGGTAAAATTGATTTAGGTGATACAGTTCCTGGCTTTGCAGCCATG
CCTGAAAGTGCTGCCTCTAAAAATGAGGCCAAAAAAAGGATGAAAGCCTTGACTGGTGAC
TCTAAAAAGGATAGTGACCTACTGTGGAAGGTTTGGTTTTCATATAGAGAAATGAATTAC
CGTCATAGTTGGTTGACACCATTCTTCATACTTGTATGCGTGTATAGCGCGTACTTTTTA
TCTGGGAATAGAACAGAATCAAACCCGCTGCACATGTTCGTAGCCATATCATATCAAGTT
GATGGCACAGACTCATATGCAAAAGGTATCAAAGATTTGAGTTTTGTGTTTTTCTACATG
ATTTTCTTCACATTTTTACGTGAGTTTTTGATGGATGTTGTAATTCGACCATTCACGGTA
TACCTAAATGTTACTTCCGAGCATCGTCAAAAGCGTATGCTAGAACAAATGTATGCCATA
TTTTATTGCGGAGTTTCAGGGCCCTTTGGTCTTTATATTATGTACCATAGTGATTTGTGG
TTGTTCAAGACAAAACCAATGTACAGAACATATCCTGTTATAACCAATCCGTTCTTGTTT
AAGATATTTTACTTGGGTCAAGCGGCATTTTGGGCGCAACAGGCTTGTGTTCTTGTTCTA
CAATTAGAAAAGCCAAGAAAGGATTACAAGGAATTGGTTTTTCATCACATTGTGACATTA
TTATTAATTTGGTCATCATATGTTTTCCATTTTACCAAAATGGGATTGGCTATCTATATT
ACTATGGATGTGTCAGATTTTTTCCTTTCTTTGTCTAAGACATTAAACTATCTGAATTCT
GTATTTACTCCCTTTGTGTTCGGCTTGTTCGTGTTCTTTTGGATCTATCTGCGCCATGTC
GTGAATATCAGAATATTATGGTCAGTCTTAACAGAATTCCGTCATGAAGGTAATTATGTG
TTGAATTTTGCCACACAACAATACAAATGTTGGATTTCGTTGCCAATTGTATTTGTACTA
ATTGCTGCGTTACAATTAGTTAACCTGTATTGGCTGTTTTTAATTCTTAGAATCTTGTAC
AGATTGATATGGCAAGGTATCCAAAAGGACGAAAGAAGTGACAGTGATTCTGATGAGAGC
GCTGAAAATGAAGAATCTAAGGAAAAGTGTGAATAA Promoter Sequence
Download FASTA
>LAG1 YHL003C
GAGGTAAAATTTTTTGAACTAATTTCCTGTCTTAAGCGGGAACCACAATTTTCTGCCAAA
GATACCGTCAAAGAGAGGGTTCTTAAGATCACGTTAGCATCCTGTTGTTCTAGCCTCTTC
TCTATAAGAGACATAACCTCTTGTCCATTATCTTCGGGATCTTCCTTCACCAAATCGCAA
ACATCTAAAATGTATTGCCAGTTATCACTTCTCAACTTGGGATCTGTTGCCTTCAACAGT
GCATTCCTTATTTTAATCGCAGATGATGACATTTTTGTCAACGGTTTCCTTAGATAGATT
TACGCATTGCCTCTGGCATGGCCCCTATATTTAACAGTTAGAATCCATTGCGTTTCATTT
ATGTAATTCGAATTTCTTAACTAATCACTAATAACGGTAAATGAGGTTAACCATTAGAAT
AATGTATATAATTACGTACAAAGGCTACCGAAGTTCTGCGGCAGTAATGTAGGGTTTAGC
TTTTGAATCAATCTTAGAGCCTGCTATCTTCCTGCACTTGCTGATTCCATAAATATAAAC
ACCTTTCGGCTAGACCGACAAAGGTCGTAGTCGTTTTTCCTTTAGGGTATTATGACCAGG
GACACCCCAGTCCGTCAAGACTAATATCGATAGTATATTACAGGTAAATAGAGATCCCTT
TTATAGAGAATTTAACGCTTTAAACTTACCTAATGCGTCATCTTCCATTTGAAATCCTTC
TTGACCGAGGGCAGCCCAGGGGTAGTGAAAAACGATGAAAAAATTCCATTTTTTTAGCGG
GAAAAGCAAATTGCAGCATCAACATTTTACGCGCTATCACTTGACAAACAAGGCAAGGAA
AACTGCAGCCCTGTACTAAGAAGGTCAAGATATTTGCCAAACGATTTCGTAAGGTTGTCT
CAATTGATCTGACTGCTTGTCTATCTAAAGTGGCAAGGTATATTAGACAGTGTTGAGAGT
GAACTCCAAGATACAGAGAAACTGAAGAAATAACGACAAC
Chr coordinates
Chr VIII from 101883-100648
