S.cerevisiae - Yeastract

Locus Information

Standard Name	SPO11
Systematic Name	YHL022C
Strain	S288c
Description	Meiosis-specific protein required for meiotic recombination; makes DNA double-strand breaks (DSB) during meiotic recombination, homolog pairing, and synaptonemal complex formation; role in meiotic DSB formation involves a topo-II-like transesterase mechanism; forms monotetrameric complex; covalently linked to DSBs through a 5'-phosphodiester bond between a catalytic tyrosine (Y135) and the DSB 5'- end; sequence similarity to a topo VI subunit from archaea, fission yeast rec12 and human SPO11
External sources	Open in SGD Open in KEGG

Gene Sequence Download FASTA View Seq	Sequence hidden
Promoter Sequence Download FASTA	>SPO11 YHL022C AATGCCCATTATGCCAATAAAGACTTGCCGCTACATACGGATTTACCATTTTTAGAAAAT GTGCCAGGTTTCCAGATTCTACAATCTCTACCTGCTACAGAAGGGGAAGATCCCAATACT AGACCCATGAATTACTTCGTGGACGCATTTTATGCTACCCGTAATGTTAGAGAATCGGAT TTTGAGGCTTATGAGGCTTTACAAATTGTTCCTGTAAATTATATATATGAAAACGGCGAT AAGAGGTACTACCAATCCAAACCTTTAATCGAACATCACGACATTAACGAGGACAATACT CTTCTGGGTAATTATGAGGCCTTGATTAAATGCATTAACTACTCTCCACCATACCAAGCA CCTTTCACTTTCGGAATTTATGATAAGCCCTCAGATCTAAATAATAATCTGGACTTGAAT TTAATTACCACCCCAGCAAAACTAACAGAGAGATTTTTGTTTAAGTCTTTCATTAGGGGG TTGAACTTGTTCGAGAGTCATATCAATGACTTCAACAATCAATTTAGATTGCAGTTGCCC GAAAACTGTTGTGTTATCTTTAACAACAGGAGAATTTTGCATGCTAACTCTTTAACAAGC TCAAACCAGCAATGGTTAAAGGGTTGCTATTTCGATTCTGATACTTTCAAGAGTAAATTA AAGTTCTTGGAAGAGAAGTTTCCTCATGACAAATAACTTCATTTTTTCAGCATAGTTATG TGATTCTTTATATTTATTTATTTTCTCTCTGTGTAGTGACAATTTTTTTTTTAATGTTTC ATGTTAAATATATTTATTTTAAGAAGCCGTCAGTTTCCTTTTGTTTCATTGAAATCAATA ACTAAAATTAAAATTATAAAAGGAATAACGTAAAAGAAAGTCTACTACCCAAGGAAAATC TACTTTATTTAGTGATTATATCCAACTAAATATCATTCAAATAACCTCACATATTTGTCT TCACCCTTAAGATTTTACGATTTACTAAGTTCACCTTCTC
Chr coordinates	Chr VIII from 64157-62961