Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
NPR3
Systematic Name
YHL023C
Alias
RMD11
Strain
S288c
Description
Subunit of the Iml1p/SEACIT complex; SEACIT (Iml1p-Npr2p-Npr3p) is a subcomplex of SEAC, a coatomer-related complex that associates dynamically with the vacuole; Npr3p may have a structural or regulatory role, supporting Iml1p function as a GAP for the Rag family GTPase Gtr1p, and leading to inhibition of TORC1 signaling in response to amino acid deprivation; SEACIT is required for non-nitrogen-starvation-induced autophagy; null mutant has meiotic defects; human NPRL3 homolog
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>NPR3 YHL023C
ATGGATGAATGTTTACCCAATTCATGTCTACTAGGTGTTCACCTCGTCATTTCAACGCAT
TCGGGGCCACAAATAGTTTATCACTACCCACCCTCCAATACAGCATTTCTAACAAATAAT
CCAACGAAGCATCAGCACCTCTATGGAAACCATGCAAATCTAAATAAAAACACAAGTACA
AATAAAGAAGAAAAACTCTTTAATTCTGGCTCTACGAAAACAGCTTCTCAAATTGCTCTA
AACGAGTCAGCGAAAAGTTACAATACCGCTATTACGCCATCAATGACAAATACTAATACT
AATAATGTGACATTACCTCCAACTAGATCGCATGCTAATACTGTAGGATCACAAAGTTCA
ATTCCTGCGGCTACTAATGGTGTAGGTTATAGAAAAACCGATATCGAAGATACTTCTCGG
ACTTTTCAATACCAAGAAACTGAATCTGAAACGTCATCATCGGGATTAAGTGACAGCGAA
TTGTCCACAGACTACTTAGACATTTCTAGCGATTCGTTTTCTATATCTTCTTCCTTATCG
TCATCTTCTTTATCTTCTTCTCCCTCAAGTTCATCCTCATCTTCCCCTCCGCAAGATGGC
TTATCAAGAACTAATTCGAGTTTCCAATCTACGGATTCAATGTCTCCAACTTCACCACAA
ATGATAATGGAAAACGATAGTATTTCAGTAGCGGAATCATATCTAGATTCTGGGACTAAT
AACAAATCAAGGGCCGCTTCCAAGAGATCCCAGAATTTCTTCCATAAATTGAGTACCAAG
AAGAGTACTGATTCAAAAACACATTCTCCAGTAAGAAAGCTTAAATCTAAGCCATCACAA
AGCACTAAAAAAGGCAACAAACTGTTAAAAAATACGTCCAATGAGACTGATGGAAATGCT
TTTACAGGAAGTTGTTCAATTTCTTCTAAAAAATCTTTATCGAGTACAGGAGAGCATAAC
CAAGAACTTCGTAATAGTAGCCTGAACGACACTCCTGGCCAATCACCTCATCATTACCAC
CATCGTTACCACCATTATCATAAAAATGCCGCGACGAGCCAACGAAATTCCCATACCCAG
TACGATGTTGAAGAAGAAGACATGGAAGTTTCGGCAATGTTGCAGGATGGTAAAATCTCT
ATGAATGAAATTTTTTTTGAAGAGGAAAACTTCCAGGATATAAATAAAATTCTAGAATTT
GATAATGATTTTGTTGCAGAATTTTGTAGCCCTGAGAGGGAAATGTGCAATACCAGATTC
GAATTCACGGTGGATAATTTCTGCTTCTTAGGCTTACCTATTCATGTAGATTCTCAAGGC
AGATGGAGAAAATCCAAGCACAAAAATAAAACCCGCTCTAAAAGATCTTCGAGTACTACA
ACAAACATCAGTAGAAAGAAATCTATCGCTTCCAAAATTTCATCACTGAGTGAGAATACT
TTGAAGAAAGTTAATAGTGGTGAAGCTGACACTGTTTATGACAGTAATATTGGTCATGAG
GCTTCTACTGATACGCCGAATTTGAGGATAAATACTGATGTCAGTGGAAACGAATTTGAG
AGAGAAAAGGAAGACTTGGGCAAAAATATGAACATGTTTCATGTATGCTTTGTTATGAAT
CCGCATTTAATCGAATATAATAAAAGGATTGATGACATGTATCAGTTTGTTGTTACAAGG
TTATCATTATTGTTAAGATATGTGCAATCAAAAACCTCGTACATTTCTAGCGAATGCCAT
ATAATTTTAAAGGAAAAAGAACGGGTACTGAAACATTCGAAAACATACCAATCTATAAGA
GGCGCAGGAAACAAGGGGAAGTATCTGTACCAAAGAATTTTAGCCAAATCTTCGTTGGCT
AGGGCGCTAACGGAATGTGTTGATAAAATCCAACGAAATGAAATCGCATGTCTTGAGATC
AATGACGATAAAGTAATTTCCTTGCAAATCCCGATTCAAAACGAGTTTGAAAAAATGCCA
AACTTCAAACTGCAACCCGTGCTAAGAGGCTCATATTTGACGTCCATTTTGAACATGAAA
TTTTTAGAAAAATCATCATTGAGAATTGAAAGTCAAAATCGTCAAAACGATCAGGCTCAA
TTCAGTGATACCAATAATAACATATACAGGTTTGGCAATAATATTAATAGTACCGGCCAC
TGTGGAGCAGCAAATGTGGATGACGGGGACGACAATGAAAGCAATTACTACTGCGACGAC
AATGATGACCTTTTAAACTATGCGCTATTATTATTGGACGAGCCAAATAATATTATTAGC
TCCCTCGAAACTTTTTCATACCAGGACGATATTGGCACTATCATATTGAAACATTTAGTC
AGAAATATCCAGCCAAATATCCCTCTAAGGTCGTATCGCTATCTGATAACTGATTTATTA
GATAACCCTTCTTCACTGGACGACCTTACTACAGAAACAAACTCATTGGAATCAAGCATA
CTGCGCTCTTGCGCATTGCATTTAATGTATTGGAGACATGCAAGAATAGTGATCCCACTA
AGCTCCAAATACACGTATATTGTTTCACCCTTGGCTCCTATTCAAGGTTATACAATAGAT
GATTATAAAAGTACTTCACAAAATGATGGGAACGTGAAAAAAATGGACGATCGCGAAAAT
AATAAGAGTGGAAGCGACAGAGTACCACTAATTTATCAAAATTCGATGTTGTTCAGATCC
AAATTCCCATCATTGCCCAGTTTACCCATTTTTTTAAGTTTGTTGTCCACGGACAAACCT
CAAGCGTACAGTAACATAATCCCATCAAGGGAACATAAGCCAGTTTACCTGAACGCGTTA
GCGTGGTTAATACAGTACGGGTATGTAACCCAATTATTGACTTTCATAAATATCCGAGTG
GACAAACACATAAAAATGGCAGTAGATGAGGATCTAGAAAAGGAAGGCTTCCGTAAGACT
AATACTGCTAGAAGGCCCAGCATGGACTACAAAAAAACTGATAAAAAGCTGGATGATGAA
GATGGGCAAAGTAGAGATGCAAACGCCAGCGAAGCGTGTTCAGGAAAGAATGAAGGCATG
CAGTCCAACGACAACAACAAAGATGTGGACGAAAAAGATAACGAAAATGATAGTCGTGTT
GATGATCGTGATGACAATGAAATAGCTATTGCGGATGAAGAAGAAATACTACACTTCGAA
TACGATGATCCAGAAATGCAACATGACTATACTATAATTTTGGAACCTGAAAGAGCCACT
GCGATTGAAAAAAGATGGCTTTATAGATGTATTTATGGTCAGCCTTCAGATATCCAGATT
CTTTTTAACAAGTTGCTCAAGTACTTCAATGGAAAGGTCCCCATGGAATTGGTTATCATC
AAAGAGGAAATTAGCAGACATGACCTAAAGAAATTGCTCAATGCTCTAGATAAGTATTTA
ATCGAGATACACCATTGGTAA
Promoter Sequence
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>NPR3 YHL023C
AAGCAAACAATTTTCCCTGGTAAGCCCTGTCTAATTCCATTTTTCCAAGATGATGCGGTC
ATCAAGTTAGGGACAACAAGTATGTGTAATATTGTAATAGTGGAAAAAGAAGCTGTCTTC
ACCAAATTAGTAAATAATTATCACAAGTTGAGTACAAATACCATGCTCATTACAGGTAAG
GGATTTCCAGATTTCTTGACAAGGTTATTCCTAAAAAAACTAGAACAATATTGCTCCAAA
TTGATATCGGACTGTTCTATATTTACCGATGCGGACCCCTATGGGATTAGCATAGCCCTA
AATTATACTCACTCGAATGAACGCAACGCTTATATTTGCACGATGGCAAACTATAAAGGA
ATTCGTATTACGCAAGTTTTGGCACAAAATAATGAAGTGCATAACAAATCCATTCAATTA
TTGAGTTTGAATCAGCGCGACTACTCCTTAGCCAAGAATTTGATAGCATCTCTGACTGCC
AACAGCTGGGATATTGCAACTTCACCATTAAAGAACGTCATCATAGAATGTCAGCGGGAA
ATTTTTTTCCAAAAGAAAGCTGAAATGAACGAGATTGATGCCAGAATTTTTGAATACAAA
TGAATAAGAATGGGAGCTGTTGCTTTATAAAAAATGTTTTTCAAGAATTGAAAACGGTTA
CATTTAAATATTATATAAATTGAAATCTTTGATAATGAATACTAGTCCAAAAAAAAATAC
AATTTCAAAAAAATAAATGCCATCTCCTAGAATCGAACCAGGGTTTCATCGGCCACAACG
ATGTGTACTAACCACTATACTAAGATGGCATATGATTTTACAATGATTCGATGGTGAATG
AGTTATAAGCCATGTAAGGATCACTAGTCTTTTTTCTTAAGTAACTTTTTCGCTTGTGAT
ATCTTGAAATACCATTAAACATAGATAAGCTATTGAAATGTGAAGAAAATTCAAAAAAAA
AAGGGAACAGAGTCATCTTTTGGGTAGAAACTAAGCTTCA
Chr coordinates
Chr VIII from 62563-59123