Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name COS8
Systematic Name YHL048W
Strain S288c
Description Endosomal protein involved in turnover of plasma membrane proteins; member of the DUP380 subfamily of conserved, often subtelomeric COS genes; required for the multivesicular vesicle body sorting pathway that internalizes plasma membrane proteins for degradation; Cos proteins provide ubiquitin in trans for nonubiquitinated cargo proteins
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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>COS8 YHL048W
ATGAAAGAGAATGAAGTCAAAGATGAGAAAAGCGTAGATGTGTTATCCTTCAAACAGCTC
GAATTCCAAAAGACCGTTCTACCTCAAGATGTTTTCCGAAACGAATTGACCTGGTTTTGT
TATGAAATTTACAAGTCTTTAGCGTTTCGCATCTGGATGCTGTTATGGCTACCACTTAGC
GTCTGGTGGAAACTTTCCAGCAATTGGATTCACCCACTTATAGTTTCACTTCTTGTCCTG
TTCCTGGGACCATTTTTTGTCCTTGTTATTTGTGGACTTTCTCGTAAGCGTTCCTTATCG
AAACAACTCATTCAGTTTTGCAAAGAGATTACTGAAGACACACCAAGTTCGGATCCTCAT
GATTGGGAAGTCGTTGCAGCAAATCTAAATTCGTACTTCTATGAAAATAAGACTTGGAAT
ACCAAGTACTTTTTTTTCAATGCCATGAGCTGCCAAAAAGCGTTTAAAACAACCCTTCTC
GAACCCTTCTCTTTAAAAAAAGACGAATCTGCAAAGGTTAAGTCATTTAAGGATTCCGTT
CCTTATATCGAAGAGGCCTTGCAAGTGTATGCTGCAGGATTTGACAAAGAGTGGAAGCTG
TTTAATACTGAGAAGGAAGAGAGTCCTTTCGACCTGGAAGACATTCAGCTCCCCAAAGAA
GCTTACCGATTTAAGCTTACCTGGATTCTTAAAAGGATTTTCAACCTGCGGTGTTTACCA
CTCTTCCTTTATTATTTTTTAATTGTCTACACGTCTGGAAATGCTGACCTTATATCACGT
TTCTTGTTTCCGGTAGTAATGTTTTTTATCATGACGAGAGATTTCCAAAATATGAGGATG
ATTGTTTTATCCGTGAAAATGGAACACAAGATGCAGTTCTTGTCAACTATTATAAATGAG
CAAGAAAGTGGTGCGAATGGATGGGACGAAATTGCAAAGAAAATGAATAGGTATTTGTTT
GAGAAAAAAGTCTGGAATAATGAAGAGTTTTTCTACGATGGACTTGACTGCGAATGGTTT
TTTAGGCGCTTTTTCTATCGTCTCTTATCTTTAAAAAAACCTATGTGGTTTGCTTCGTTG
AACGTTGAGCTATGGCCATACATTAAAGAAGCGCAATCGGCCCGCAATGAGAAGCCCCTA
AAGTAG
Promoter Sequence
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>COS8 YHL048W
ACTCAATTTATATACACTTATGCCAATATTACAAAAAAATCACCACTAAAATCACCTAAA
CATAAAAATATTCTATCCTTCAACCATAGTACATAAACACACTCAATTGCGTATCAATAC
CACCATGACGTCATTAACTTAAATGTTCCTTAATACCGTCATACCACTATGCTCTATTCC
ATATATTGTAATATAACTGTACTCTATAGTCATACAGACGCTTTTACTTCACCCTATCTT
CTCATACTATTGTCATAGAATCTCACACTGACGCATGATTAAAACGAATAATTTTTACTA
TAAGGCCTCCCATCCGTGCTCTACCCTTTTGTTTGCAATATTTATACAGAATCTCAAAGC
AAGCGGGAGAAGTGGTGATTACCCAGATGTCATGCATGATCTGAGCACCACCGTACCTCT
AGGTTTTGCCTTGATCAATTTTACAGTGACACCAAGCATAAGGATAAAAAATGGTATTGA
AAGGTTGTCCACATTTGTAAGTAACTTGGTTCTATGAATCTTCATGTCAGATACGTAGGA
CGGACTCTTTCCTGTGTAAATATTTGTGACAGCTACGTCTATTTTCTACTAGATGTTTAC
ACAGTTTTGTCACAGGAAATCTACGCTTAAAATATGTATTTCATTCAAGCGGTAACCGCT
GTACGAGCAGTGACATTGCTGGTCGCACCTTAAATGTAAACCAAAGTTACGGCACACCGT
GATGCACCCGCATTAAAGTTTTGTAAATTCGTTATTACGATTATCGAGTTGGCTAGATAG
AAAACCGGAAATGAAATGGATGCCCTTTTCGAATAGCTGAGTTTCTTTGCCTAAAATAGC
CCAATATTGTTTCCCTTTTTCTATCACGAGGTTACTGAGCCATTGCATGAACGCGCGCGC
CTCGGCGGCTTTTTTTTTCTGCTGTGCTGTATAAAAGCGAAAAGTCAGAAGTTACTATTT
CGAATAAAAAACCCCTCGAACTGCCATCTCACTACCGAAA
Chr coordinates Chr VIII from 6401-7546
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