Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
BRL1 Systematic Name
YHR036W Strain
S288c Description
Essential nuclear envelope/ER integral membrane protein; interacts and functions with Apq12p and Brr6p in lipid homeostasis; mutants are defective in nuclear pore complex biogenesis, mRNA nuclear export and are sensitive to sterol biosynthesis inhibitors and membrane fluidizing agents; identified as a dosage suppressor of a temperature sensitive mutation in the major karyopherin, CRM1; homologous to Brr6p External sources
Open in SGD
Open in KEGG
Gene Sequence
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Sequence hidden Promoter Sequence
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>BRL1 YHR036W
CACTAGGTCACAATTCAGCTGAAGCTCCTATACAGTTTCAAACCACTTTTGAAAATCAAA
CGGAAAAATACATAAGAATTGAAACCCTCTTATTGCCAAAAGCCAATAGATCATTTGGGG
CACAAAATGAAATTGTGTTTTCAATGAAAAAGATAGCCTCACGAATTATCGATAGCTTTG
CTTACTCATCCAAGCACACTAAAGAATTGATGAAGCAATTGTTTCTATTACCAAATCAAA
TCCGGGGAAAAGACGTAGATATGGTCAATCTGATACAGTGGTGTTATCATATATATAGGT
CTCCAATTCTATCGGTTCGGAATACTTCACCTGATGAAAGGTACCTTTTTCTTCACCGAA
TAATAAACGCTTCTAAAGACACATGCCTTTCATTATGCAAACCCTTCATCTGGAGTTACA
GTGATTTGAAACACGACTGGATCGTGTTGGATGTCCCATTAACAAGAGCCCAGATACTTC
AAGATGATAAAACCACCATTTGTGTAGATGGTGGCTCGTACTTAGTTTTAAGAAGGGGAA
AACTTTTGGAAAAAGAAGGTCGCGAGCTCTGTTGCAAGCTTTTAAATGACTTGCAAAGGT
TTCCGCAGCCATTATATGTTGAAACTAAAACCGGTGGCAGTCAGGACCGTTTCTTGAAAA
GCAAAATTATTCCCTTGGACATCACTGACAAGGAAACTCTTGGTACAGAGGATATGACAT
TCAATGAATATTTCAACTTGTTCACCGATCTAAGTGGAAGCAAATAACTCGCTAAATATT
CTTGCTGCACTTTGCGACGCCTGTATTGGCGAAAACAAAAAGTAAAGAAAAAAAAACTTT
AGATGAAATAGAGCAAAATTCCCTAAGACAATAGAAGATACAAAAGCAAGTTGGGCCCTT
AATTTCATCAAAGGTATAGCATCTCATCAAATAGTCGCTTGTTTATCGCAATACTTGCTT
ATTGAGTAGTTGTATTATAACGTTATATAGGATCTTCCAT
Chr coordinates
Chr VIII from 180345-181760
