Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
IRE1 Systematic Name
YHR079C Alias
ERN1 Strain
S288c Description
Serine-threonine kinase and endoribonuclease; transmembrane protein that mediates the unfolded protein response (UPR) by regulating Hac1p synthesis through HAC1 mRNA splicing; role in homeostatic adaptation to ER stress; Kar2p binds inactive Ire1p and releases from it upon ER stress External sources
Open in SGD
Open in KEGG
Gene Sequence
Download FASTA Hide Seq
>IRE1 YHR079C
ATGCGTCTACTTCGAAGAAACATGTTAGTATTGACACTGCTCGTTTGTGTGTTTTCATCC
ATCATTTCATGCTCAATCCCATTGTCGTCTCGCACCTCAAGGCGGCAGATAGTGGAAGAT
GAAGTTGCCTCCACTAAAAAGCTCAATTTCAACTATGGTGTGGATAAAAATATAAACTCG
CCCATTCCTGCTCCAAGAACCACTGAAGGTTTACCAAATATGAAACTCAGCTCATATCCA
ACTCCTAACTTATTGAATACTGCTGATAATCGACGTGCTAACAAAAAAGGACGTAGGGCT
GCCAATTCTATAAGTGTACCCTATTTGGAGAATCGTTCCTTGAACGAACTGAGTTTATCA
GATATACTAATCGCAGCCGACGTTGAGGGTGGACTTCATGCTGTAGATAGAAGAAATGGT
CATATCATATGGTCAATCGAACCAGAAAATTTTCAACCTCTGATAGAAATACAAGAACCT
TCGAGGTTAGAAACATATGAAACGTTGATTATAGAACCTTTCGGTGATGGGAACATTTAC
TACTTTAACGCCCATCAAGGGTTACAAAAACTGCCTTTATCCATACGACAACTTGTATCA
ACTTCCCCGCTGCACTTGAAAACAAATATTGTGGTTAATGACTCTGGAAAAATTGTTGAA
GATGAAAAGGTCTACACTGGATCGATGAGAACTATAATGTATACTATAAACATGTTGAAT
GGTGAAATTATATCAGCGTTCGGACCTGGTTCAAAAAACGGGTATTTCGGGAGCCAGAGT
GTGGATTGCTCACCTGAGGAGAAGATAAAACTTCAGGAATGTGAAAATATGATTGTAATA
GGCAAAACTATTTTTGAGCTGGGAATTCACTCTTATGATGGAGCAAGCTACAATGTCACT
TACTCTACATGGCAGCAAAATGTTTTAGATGTTCCCCTAGCGCTTCAGAATACATTTTCA
AAGGACGGCATGTGCATAGCGCCTTTCCGTGATAAATCATTGCTAGCAAGCGATTTAGAT
TTTAGAATTGCTAGATGGGTTTCTCCGACATTCCCCGGAATTATTGTTGGGCTTTTCGAT
GTGTTTAATGATCTCCGCACCAATGAAAATATACTGGTACCGCATCCCTTTAATCCTGGT
GATCATGAAAGTATATCGAGTAACAAAGTTTACTTGGATCAGACTTCGAACCTCTCCTGG
TTTGCATTATCTAGTCAGAATTTTCCATCTTTAGTCGAATCAGCTCCCATATCAAGATAC
GCTTCCAGTGACCGTTGGAGGGTGTCTTCAATTTTTGAAGATGAGACTTTATTCAAGAAC
GCAATCATGGGTGTTCATCAGATATATAATAATGAATATGATCACCTTTATGAAAACTAT
GAAAAAACGAATAGTTTGGACACTACGCACAAATATCCACCTCTGATGATTGATTCGTCC
GTTGATACAACCGATTTACATCAGAATAACGAGATGAATTCACTAAAGGAATACATGTCA
CCAGAAGACCTTGAGGCATATAGAAAAAAGATACACGAGCAAATATCGAGAGAATTAGAT
GAAAAGAACCAAAATTCTTTGCTACTGAAGTTTGGAAGTCTAGTATATCGAATTATAGAG
ACTGGAGTATTTCTGTTGTTATTTCTCATTTTTTGTGCAATACTACAAAGATTCAAAATT
TTGCCGCCACTATATGTATTATTATCCAAAATTGGATTTATGCCTGAAAAGGAAATCCCC
ATAGTTGAGTCGAAATCGCTAAATTGTCCCTCTTCATCGGAAAATGTAACCAAGCCATTC
GATATGAAATCAGGGAAGCAAGTTGTTTTTGAAGGTGCTGTGAACGATGGAAGTCTAAAA
TCTGAAAAAGATAACGATGATGCTGATGAAGATGATGAAAAATCACTAGATTTAACCACA
GAAAAGAAGAAGAGGAAAAGAGGTTCGAGAGGAGGCAAAAAGGGCCGAAAATCACGCATT
GCAAATATACCAAACTTTGAGCAATCTTTAAAAAATTTGGTAGTATCCGAAAAAATTTTA
GGTTACGGTTCATCAGGAACAGTAGTTTTTCAGGGAAGTTTTCAAGGAAGACCTGTTGCG
GTAAAGAGAATGTTAATTGATTTTTGTGACATAGCTTTAATGGAAATAAAACTTTTGACT
GAAAGCGATGATCACCCTAACGTCATACGATACTACTGTTCAGAAACAACAGACAGATTT
TTGTATATTGCTTTAGAGCTCTGCAATTTGAACCTTCAAGATTTGGTGGAGTCTAAGAAT
GTATCAGATGAAAACCTGAAATTACAGAAAGAGTATAATCCAATTTCGTTATTGAGACAA
ATAGCGTCCGGGGTAGCACATTTACATTCTTTAAAGATTATCCATCGAGATTTAAAGCCT
CAAAATATTCTCGTTTCTACTTCGAGTAGGTTTACTGCCGATCAGCAAACAGGAGCAGAA
AATCTTCGAATTTTGATATCAGACTTTGGTCTTTGCAAAAAACTAGACTCTGGTCAGTCT
TCATTTAGAACAAATTTGAATAACCCTTCTGGCACAAGTGGTTGGAGGGCCCCAGAGCTG
CTTGAAGAATCAAACAATTTGCAGTGCCAAGTCGAAACGGAACACTCTTCTAGTAGGCAT
ACAGTAGTTTCATCTGATTCTTTTTATGATCCGTTCACCAAGAGGAGGCTAACAAGATCT
ATTGATATTTTTTCTATGGGATGTGTATTCTATTATATCCTATCCAAAGGGAAGCATCCA
TTTGGAGATAAATATTCACGTGAAAGCAATATCATAAGAGGAATATTCAGTCTTGATGAA
ATGAAATGTCTACATGATAGATCCTTAATTGCAGAAGCTACAGATCTGATCTCCCAAATG
ATTGATCACGATCCGTTAAAAAGACCTACTGCTATGAAAGTTCTAAGGCATCCGTTGTTT
TGGCCAAAGTCGAAAAAATTGGAGTTCCTTTTAAAAGTTAGTGATAGGCTTGAAATTGAA
AACAGAGACCCTCCAAGTGCCCTGTTAATGAAATTTGACGCCGGTTCTGACTTTGTAATA
CCCAGTGGAGATTGGACTGTCAAGTTTGATAAAACATTCATGGACAACCTTGAAAGGTAC
AGAAAATACCATTCATCAAAGTTAATGGATCTATTAAGAGCACTTAGGAATAAATATCAT
CATTTTATGGATTTACCTGAAGATATAGCAGAACTAATGGGGCCGGTACCCGATGGATTT
TACGATTACTTCACCAAGCGTTTTCCAAACCTATTAATAGGTGTTTATATGATTGTCAAG
GAAAATTTAAGTGACGATCAAATTTTACGTGAATTTTTGTATTCATAA Promoter Sequence
Download FASTA
>IRE1 YHR079C
GTCTTATCCTTGCCATAAACAGAAGACAACTTGCAAGTATGAACTATTTGGAAACACAGT
TAAATAAAAAGCAAAAACAGATACAGGAATACGAAAGTATGAATGGCAACCTGATAAAGA
TGTTTGAGCAATTGTCTAAAGAAAAGAAAAAGTATGTAGCTATTTTTTCCAGTCGGCAAA
AATCGGTATAACAAACAAAAAATATTTAGTTTCTGTTATTAACAGAACTTGTCAAAGTGA
TGAGACACCAAAAAAAATTTCCTCGACGTACATTAAAGAGTTAAAGGAGTACAACGAATT
GAGAGATGCCGGTTTAAGGTTGGCCCAAATAATTGCTGATGAAAAGCAATGCAAAATTAA
GGATGTTTTTGAAGAGATCGGTTATTCAATGAAGGACTAATGGGCTTTTAGGGACAGTTC
TATTCTTCCAACGTGCGAAGCGTTCCAATGAAACTCTGCTGCGCGCTGAAAACTATATAA
AAAAAAAAAAAGATAAAATTACAAAGAAGTAATGAACTTAAATGCTATTATACAGTTACT
AATTAAGCTGCGTAGTGTGAAATATATTGATAGTTGTAGTTTTGAGGTTTTATTACCCTC
TGTTATATAATAGGTTTTCGCTATTTTATTGCCGAAAATCAAGACGGAGCGTAAGCCTCT
TCGGGCAATACCTTCGACTATTCCAACAATAAAATTTAAAAAAAGAGATTAATCACATAG
TAACAAGAAATAAACGAAAAACATATCATAGGAGATCAATGAGCCAACTTCACATAAACT
AACAGTGAAAAGTCTATAACAATATTAATTTTACACAATTAAATCTACACTATAACTGGC
ACTGTTAATAATCGGTAATCTGCTAAGTAACTTTTTTTTCTCATTCACAAAGCATCGTTT
TCCTCTTCCCCACGTCCATTATCACTTTTCTCCATATCACCCTTCATACACATTAAAAAA
ACAGCATATCTGAGGAATTAATATTTTAGCACTTTGAAAA
Chr coordinates
Chr VIII from 261591-258244
