Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name DMA1
Systematic Name YHR115C
Alias CHF1
Strain S288c
Description Ubiquitin-protein ligase (E3); controls septin dynamics, spindle position checkpoint (SPOC) with ligase Dma2p by regulating recruitment of Elm1p to bud neck; regulates levels of eIF2 subunit Gcd11p, as well as abundance, localization, and ubiquitination of Cdk inhibitory kinase Swe1p; ubiquitinates cyclin Pcl1p; ortholog of human RNF8, similar to human Chfr; contains FHA, RING fingers; DMA1 has a paralog, DMA2, that arose from the whole genome duplication
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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Promoter Sequence
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>DMA1 YHR115C
TTTTCGGCCATAAGAGCTTCTTATGTTCGGTATATACAAGTATGTAGAGATATATACAAA
AAATTCTTTATTCGCACTTTGAAAATCCAATTTAGCTTGCTTATTTACATACCATTGCGA
ATTAGTTTTTCACATTGCACTAGAGTGTGCTGTGGCTGCCTGTCGGAACACTACGTCGCG
TAGTGGCGATCTATATAGAAAACAGATCACAGCTGAACAAACAAGAAGAAAAGGCTGCCT
CATTCCCACTGCTGTCTGTTTTTCCTCCTGGCTGTCAGCCATTGTTTCTTGCATTCGCGG
TATGCGTCAAAATATTCTTGGCACTTGGATCGGTCGTAATCGTTGCGCTCGAGGCACTGA
AAACTGAGCTTGGAGGACTCCTCACAAGGATCATAGTACTGACTGTCAGCCTTTAACGCG
AATTTATACTTATTGACCGGGTTCTCCGGGTCGTCTGGGTAGTATTGAAATGACGACGGA
TCGTCGCTCTTTGGTACATAGTTGACTTTGGTTCTGTCCGTTACGGGTCCACTGGCCGCT
GGTGGCGTGGAAGACGAAGATGGTTGTGAATTGTTGCTGCTTGTAGAGCCACTGTTGGTA
TTTGTGGTATCCCTATTATCGTTGGTCATGGTCATACCGTTGGAGATAGTGGAGAGACTA
CTAGTTTGCCGCCTGGTGGGGCTGGGCTTCTCCATTCTCTTTAAGCGCTCTCGTGAGAGA
ATATCACTGTTTACGGCCCACAAAGAGAATGAGAAAATTGATAAACCTTAGCATTGGGAT
CAGCAGGAGCCTTAGAATTCTGGGTGTGAACAGAAACACATTAGTGCATTAGTGTATAGG
TTCGATATTATTCAAAGAGGAACTCGGTGTACGGCTCAACTGTAAACCGTACTTCTCGTT
CTTTGTTCACTGCCCTGTTTCTGACTCTTGTGCCGTGAGCTTTTCTTCTTACAGTGTCGA
TTTCCTGTGCACATACGTTCTGTATAGTGGTTATTCCTGG
Chr coordinates Chr VIII from 341359-340109
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