Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
DMA1
Systematic Name
YHR115C
Alias
CHF1
Strain
S288c
Description
Ubiquitin-protein ligase (E3); controls septin dynamics, spindle position checkpoint (SPOC) with ligase Dma2p by regulating recruitment of Elm1p to bud neck; regulates levels of eIF2 subunit Gcd11p, as well as abundance, localization, and ubiquitination of Cdk inhibitory kinase Swe1p; ubiquitinates cyclin Pcl1p; ortholog of human RNF8, similar to human Chfr; contains FHA, RING fingers; DMA1 has a paralog, DMA2, that arose from the whole genome duplication
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>DMA1 YHR115C
ATGTCTACTAATACTGTTCCCTCATCTCCCCCAAACCAGACGCCACCTGCTGCTTCTGGC
ATCGCTACCTCTCACGATCACACCAAGTTCAACAATCCCATCAGACTACCGATATCCATC
TCTCTCACCATTAACGATACGCCTAACAATAACAGCAATAATAATAGCGTTAGCAATGGT
TTAGGTATTTTGCCCTCGCGTACGGCTACTTCTTTAGTCGTTGCAAATAACGGTAGCGCA
AACGGCAATGTTGGTGCTACTGCTGCTGCTGCTGCCACTGTGGAGACGAATACAGCCCCC
GCGGTGAACACTACAAAGAGTATCCGCCATTTCATATATCCTCCAAACCAAGTCAATCAG
ACGGAGTTTTCACTTGATATACATCTCCCACCAAATACCTCGCTACCGGAACGGATAGAC
CAATCTACTTTGAAACGCAGAATGGACAAGCACGGGCTTTTCAGCATTAGGCTAACCCCG
TTTATAGATACTTCATCCACGTCTGTGGCTAACCAGGGTCTTTTCTTTGACCCCATTATC
AGGACTGCGGGCGCAGGCTCGCAAATTATCATCGGAAGATACACCGAAAGAGTAAGAGAG
GCAATTTCCAAAATTCCAGATCAGTATCATCCCGTAGTGTTCAAATCAAAAGTGATATCC
AGGACCCATGGGTGTTTCAAAGTTGATGACCAAGGAAACTGGTTTTTGAAAGATGTCAAG
TCTTCCAGTGGGACCTTTTTGAACCACCAGCGTCTATCTTCTGCGTCTACCACTTCTAAG
GACTACCTTTTACATGACGGAGATATCATACAGCTGGGTATGGACTTTCGCGGCGGGACG
GAAGAGATATATCGTTGTGTTAAGATGAAAATAGAATTGAACAAGTCTTGGAAATTAAAG
GCCAATGCATTTAATAAAGAAGCCTTGAGCCGAATAAAAAATCTACAGAAACTAACTACT
GGTTTAGAACAAGAAGACTGTTCCATTTGTCTAAACAAAATAAAACCTTGCCAAGCCATT
TTTATATCACCATGTGCCCATAGTTGGCATTTTCATTGTGTAAGAAGATTGGTTATTATG
AATTATCCTCAATTCATGTGTCCGAACTGTAGGACAAACTGTGATTTGGAGACTACCTTG
GAATCCGAATCTGAATCCGAATTCGAAAACGAGGACGAAGATGAGCCAGACATTGAAATG
GATATAGACATGGAAATAAATAACAATTTAGGTGTTCGCCTAGTAGATTGA
Promoter Sequence
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>DMA1 YHR115C
TTTTCGGCCATAAGAGCTTCTTATGTTCGGTATATACAAGTATGTAGAGATATATACAAA
AAATTCTTTATTCGCACTTTGAAAATCCAATTTAGCTTGCTTATTTACATACCATTGCGA
ATTAGTTTTTCACATTGCACTAGAGTGTGCTGTGGCTGCCTGTCGGAACACTACGTCGCG
TAGTGGCGATCTATATAGAAAACAGATCACAGCTGAACAAACAAGAAGAAAAGGCTGCCT
CATTCCCACTGCTGTCTGTTTTTCCTCCTGGCTGTCAGCCATTGTTTCTTGCATTCGCGG
TATGCGTCAAAATATTCTTGGCACTTGGATCGGTCGTAATCGTTGCGCTCGAGGCACTGA
AAACTGAGCTTGGAGGACTCCTCACAAGGATCATAGTACTGACTGTCAGCCTTTAACGCG
AATTTATACTTATTGACCGGGTTCTCCGGGTCGTCTGGGTAGTATTGAAATGACGACGGA
TCGTCGCTCTTTGGTACATAGTTGACTTTGGTTCTGTCCGTTACGGGTCCACTGGCCGCT
GGTGGCGTGGAAGACGAAGATGGTTGTGAATTGTTGCTGCTTGTAGAGCCACTGTTGGTA
TTTGTGGTATCCCTATTATCGTTGGTCATGGTCATACCGTTGGAGATAGTGGAGAGACTA
CTAGTTTGCCGCCTGGTGGGGCTGGGCTTCTCCATTCTCTTTAAGCGCTCTCGTGAGAGA
ATATCACTGTTTACGGCCCACAAAGAGAATGAGAAAATTGATAAACCTTAGCATTGGGAT
CAGCAGGAGCCTTAGAATTCTGGGTGTGAACAGAAACACATTAGTGCATTAGTGTATAGG
TTCGATATTATTCAAAGAGGAACTCGGTGTACGGCTCAACTGTAAACCGTACTTCTCGTT
CTTTGTTCACTGCCCTGTTTCTGACTCTTGTGCCGTGAGCTTTTCTTCTTACAGTGTCGA
TTTCCTGTGCACATACGTTCTGTATAGTGGTTATTCCTGG
Chr coordinates
Chr VIII from 341359-340109