Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
NSG1 Systematic Name
YHR133C Strain
S288c Description
Protein involved in regulation of sterol biosynthesis; specifically stabilizes Hmg2p, one of two HMG-CoA isoenzymes that catalyze the rate-limiting step in sterol biosynthesis; forms foci at the nuclear periphery upon DNA replication stress; relocalizes to the cytosol in response to hypoxia; homolog of mammalian INSIG proteins; NSG1 has a paralog, NSG2, that arose from the whole genome duplication External sources
Open in SGD
Open in KEGG
Gene Sequence
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>NSG1 YHR133C
ATGGGCAAGAAGAAGAGTAAGAACCAATTAAACACTGGAGGTGTTCCTAATGGTGTCCAT
AATACCAAGAAAGAGGCAGCTTTGCCACCTTTGGGAAATAAGCTGGGAAGCGCAAGTTTT
ACAGCTATAAATACGCTGACTAAGCCCGCTTTGTTTTCATTTTATGATGACGATATTACC
AAGAATGAAGGTAATGTTTATGACAAGGCTTTATTGTCTAACGCCTCTCAATTGGAAATG
GTTCCGCCATCCGCGACTGCGAGACACGAAAGGTCATTGTATGCGAAAATAATCAATACT
ATTGCTGCATTTTTTATTCTATTCATAGCAGGAATACTCTTCCCCATGATATCAGAATGT
TTGTTTGATAATGACCAATTGGCAAAGGGAGATATCGTATCCTTTTTAAAGCATGGTATA
GAAATTAAGAACAAGATCGTCGCGGAACCTGACATGGTGCCTGATTGGGCTGTATTTGGT
ACTGAAGGTGTTATCTTTGGTTCCATAGTACCATTCATTGACTCTTTCGTTCGTTATCAA
CACCAGCCAAAAACCAGGTCATCAGTTTACAAAAACACCCTAGGATCATTTATAAGATGT
GCCAATACTCTTTTGGGCTTAATATTTGGTATTAGGAAACTTGAATGGTCCTCCTCTTTG
CAGGCAGCTGGTGCATGGAGCTTATTAAACATTGTTCTGTGGTTGTTCTTTGATGGCACT
TTAACCGTTTTTTTCCCAGGTCTAGTAATTGGTGCCCTTAGTGCGTTCACTTGCTCACAA
TGTTTCTCGCAGTTGTCACTGGCGTTGTATTTTATAGATTTCTATTTTTTTGGGTTTTTG
ATGTTCAGCAAGTTGGGCAGATATTTATTCAATTAA Promoter Sequence
Download FASTA
>NSG1 YHR133C
ATACTTATAATTTTCGAGTTCTTCGCTGTGGACAAGAGATTAAGTGAGATCAATAACTTC
GATAAGAGTATCTCCCGGGAGTACCTCGTCATCATCATCAAGGATTACAACTTCTAAGGA
GCTGCTAATATTATCACTTATTATTTGATCTTTGTTATTCTTCGTCTCTCCGCACCAGCG
ATCATCTCTATATCTCCTTTCGGCTGCAAAAGCCGCCAACTCTCTCGGGGAATTACCTCT
ATCTATAGATGATATACCCTCTGGATGCAAACTCCCTAACTTCACACCTTTGCCCCTTTT
TCTCACTATCCCTGTGTTAGTACTTATTCCTGTCATAGGATATCTATTTGAACGTAAGTT
TGCTCTTCCACCGAGACGTTGACCGTTCCCCAAAAATGTGTCGTACAAACCTCTTTGTTC
AATAACCCATTGCCTTCCAATCAACTCATCTAGCTTATTGTAGAACTTTTTGTCGTGTGG
ACCGAATAAATTGTGAGTTAATTCGTGCAGCATGGTGCCCATTATACACTCCATGGGTAA
AAATTGGAACTCATCCGTGGAGCATCTTAACCGTAACATTATCTTAGATCCATGGTTGAC
GTTCATTCCCAGGAGTCTTTGATCACGTGGGTAAAACTCCACCAAGTTGGTCACTTTGAA
GTGATTTTCCTTCATTAGATAGGAAACTTTATGTGCGATTTCCTTTATTAAATTTAGCGC
ATCTTCCTTATTGGGCTTACTTTGCAAAACAGCCACTTTTTGAATGTGCGGGTTCTTGTG
AGGGATTCTCTGGGAGCCCGCCATATCATGGTATTTTGCCGATGGGCTTTTTATTCCTTC
TGTCTTCATTAATCAATCTCTCTTATTTAGAATATCTTCAAAATATGCGTTGTTACAAAA
TACAGCGCAAAAGAAAAAGTGTCAAAATTTCTTCACCAAACTCACCTTTTGGTATTCAGA
GCAAGTGAGAAAAAAAAAATTTAAACAGAGGAGGTTACTA
Chr coordinates
Chr VIII from 371597-370722
