Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
RTT107
Systematic Name
YHR154W
Alias
ESC4
Strain
S288c
Description
BRCA1 C-terminal domain protein needed for recovery from DNA damage; implicated in Mms22-dependent DNA repair during S phase; involved in recruiting SMC5/6 complex to double-strand breaks; DNA damage induces phosphorylation by Mec1p at one or more SQ/TQ motifs; interacts with Mms22p and Slx4p; has four BRCT domains; has a role in regulation of Ty1 transposition; relative distribution to nuclear foci increases upon DNA replication stress
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>RTT107 YHR154W
ATGAGCACATCACTTCTGTTTGAGCAGCTAAATTTTTTAATTTTAGTGGCAGCAGAGGCT
GAGCTTCCCATCGCTCACTCTACTAGAAAGCTTTTGATGGATAATTCATGCAATAACTGT
CAAATATACGAGCTTTATAACGAAAATTTGAAAGATGTCAAGACGGATAAAGATTGGTTC
ATGAACAAATTCGGCCCGCAAACAGTACATTTTGTCATTAGTAATACAATCAACTTTCCT
TTTTATAAGATAGTTTATTTCGATCTTTTGATCCCGGTGGTATCACACACTTGGGTCCAG
GATTCGGTCAAGACGAAGAGACATTTGAGGACAAATATGTATTCACCTAACCCATTTCAT
TTGCTCCGAGACTGTCAAGTATATATTTCCAAAAGCTCGTTTAATAAGTGTGAATACATA
TTATACTCTGATTTGCTTCATTTATTAGGAGGCACTTTAGTCAATTACATCTCAAATAGA
ACGACGCATGTGATTGTTCAAAGTCCCCAGGACCCGATCATAGCAACGGTCAGTAAATTG
ACATTTGGCTCTTTTTCCTCTTCATCGACCAACAAGCACACCGAAAAGCCTTTGAGAGAG
TGGAAATTTGTCTATCCAATATGGATATTATATCATTTCAAAATGGCGAAGCCCTTGAAG
GGCGAGCTTGCTACTTTGTGTGAGCTTGATATGCAGGACACCAGTGAGGAACAGTTATTC
GCAAAATGGGAAGAGGTTATTGGCGATAAGCAGACATCATCATCGCAGCTTACTCTTCAT
CCAAACAAAACTTTATTCAAAAATCACCACTTTGCTATCTCACCAGATTTAAACTTTTTC
ACACCTTTGTATTGGTTTTTGAAAGGATTTATCGAGGATTTGGACGGCAAAGTAACTCCG
TTGAGTTTTTCTGACGATCTGAAGTCTGTTTACCAAGCTTTTCCTGATATTGACTGTTAT
ATCGGCCACTCTGCTAACTCACCGATACTAGAAAAAACCAAAAGCATTAAACCGGAAATT
CATGTTGGGAACGTAAGTTGGTTGTTTTATATGTTTGCGCTGCAAAAATTTACACCTGTA
TCGCAATGTAAACTTATTCACCAACCATTTCATGCGAAATTATTTACTTCTAAGGAATTA
ACAGTCGCGTACACTAATTATTTCGGCTCCCAAAGGTTTTATATTCAGAGGTTAGTAGAA
ATATTAGGAGGACTTAGCACACCTGAACTAACAAGAAAAAACACACACTTGATCACGAAG
AGTACAATTGGCAAAAAATTCAAAGTCGCAAAAAAATGGTCACTGGACCCGCAAAATGCC
ATTATTGTGACAAATCATATGTGGTTAGAGCAATGTTATATGAATAATTCCAAGTTAAAC
CCCAAAGACAGTAGATTTCAAAATTTTAAATTGGATGATAACATGGGATGGAATATCGGC
CAAATAGGAATGGATCATTCATCTCTCCCAACTCCAAAAAACCTATCGATGGTGACTTAC
GACACGCAATCCATATCAGAGAAGCCGCCTCCCACAAATGATCAAATGGATCAAATTAAC
GATAACACCAATGTATTATCAAAGAAAGATGGTACGCCCATTAGTAGTTTTGAGAACTCA
ATTGATGAAAAGATTGACAAATTACAAAAAATATCAGGAGAGGTGGCTGTAACCCATTCT
GGAGATTTAGAACGGAGTTTTGTTTCCAGACCTTCAAGGGCAAGTTTTCCAGTAGTTGAC
AGTAAAAAATCTAATTTACAAAAGAAAGACTCAAACTCAGATATTAGTATGGAAACAGAG
GTTTTCTGTGAAGGACATGAAAAAAGAGAAGAAAAGGAGTTTACGAAACCTATTACGGAG
TATGATGCACCTAAGAAACAAGAAATAAGGGAACAGTCACGCAAGAAGAATGACATAGAT
TATAAAAAAGAAGAGGAAGAAACGGAGCTGCAAGTTCAGCTAGGACAACGAACTAAACGA
GAGATCAAAACTTCGAAGAAAAATGAAAAGGAGAAAGAAACCAATGAATGTCACATTGAA
GTAGATCAAATGACGAATGAAAAGCAAGGGGAGGAAAGTACAGGAAAACTGATTTCTACG
GAAGACGTCACTTCTAAAAAAGATACAGATAAATTCTCGCATTTGTTTGAAGGATTATCT
GATAATGATGATCACATTAATGACGAAAAACCGGCAGTTAATTCCAAATATACCACACCC
AAGACGTCTCAAAATATTACGAGTGGCGTTGATACTCCAACCACCGCGCAAACGCAAGTT
TTTATGCCATCAAGTGGCAATTCAAGGTTAGCAAAGACACAAGCTGCGAAGAGATTGCAT
ACAGATATTGAATCATTAAATGAATTTCAGAAAAACTTTAAAAGGAAGAGAATTGATAGC
GAGGAGATTTCATTGTCCCAAGATGTTGAAAGGTCAAATAATAACAAAGAACTGGCTACT
AAAGCGGAAAAGATATTAGCTAGATTTAATGAACTACCAAATTATGACCTAAAAGCGGTT
TGCACCGGTTGTTTCCATGATGGATTTAATGAGGTTGACATCGAAATATTGAACCAACTA
GGTATAAAAATTTTTGACAATATTAAAGAAACGGATAAATTGAATTGTATTTTTGCTCCA
AAGATTTTGAGAACCGAGAAATTTTTAAAAAGCTTAAGTTTTGAACCGTTAAAATTCGCA
TTGAAACCTGAATTTATTATTGATTTACTGAAACAAATTCATTCTAAAAAAGATAAACTT
TCTCAAATAAATATAAACTTGTTTGATTATGAGATAAATGGAATTAATGAGAGTATAATA
TCAAAAACCAAACTACCTACTAAGGTGTTCGAAAGAGCGAATATTAGATGCATTAACTTA
GTCAATGATATACCGGGTGGTGTAGATACAATAGGCTCTGTTCTAAAGGCACATGGTATC
GAAAAAATCAACGTTTTACGTAGTAAGAAATGCACATTTGAAGACATAATCCCAAATGAC
GTTTCTAAGCAGGAAAACGGAGGCATTTTTAAATACGTACTTATCGTCACCAAAGCTTCA
CAGGTTAAAAAATTTACCAAACTGATTAATGATCGTGATAAAAACGAAACAATTTTGATT
GTTGAATGGAATTGGTGTGTTGAATCAATTTTTCATCTCAATGTTGATTTTACATCAAAG
AAAAATGTTTTGTATCAAAAGAAAAATAACTAA
Promoter Sequence
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>RTT107 YHR154W
CTTTCTAGTCATCCAAAAATAGCCAAATGCTACACTAAACCAATAAGCAAACGAGTACAT
AAAGAATAAGTAAATAATAATTCAACAATACCTGATTTTTTTTTTCTTACATTTTTTTTA
TTATTCATTAAAAGCAACCACCAAGCTTTCCAAATTATGAAACCTTGATAAAATGGCTTC
AAAATCTTGATCTGGAATTCCGTTTTTTTTGAAGAGGTCGAAAATTATTTGCTTGATTAG
AATTTCAAAATCAATAAACTCGTCCATATCCACGCTGTTCCGTGTCAAACGCTGGTTAGC
TTTAAAAGCTAGAAAATATTGATTGTTTTCAACATATCGACTTCTGTCTACTGGTGTAAC
CTCTGTAATAAAGTAGCGGGCACCCGTTTTCGATGGTCCATTTATTAGATCTAGTGACCT
CTCCAATAAGATATCCCAATAAGCTATTGAGAATTTCAAGCGCGTGAAATTCAAATTTAT
CATCAGAGAACGATGTGCGGGAACTCCAGGGCTTTTCTGTATTTTCTCATAGACATTATT
TATCAGTAATTGCAGCTGTGTAACAATAAAATTGACGCCACTTTCTTCGTCTTGTAGCTC
CTCGTTAAGCTGCGAAATTAACCTGCTCGTATTCACAGTAACACACTTAACCACAGAATG
TTCTTCGACATTAGAAATCTCTTGTATTTTTTGTACATCCCAAAAGAATTCAGACATTTC
TATTGAACCATTCCAGAAATGTTGTTCCAGAAGTTTATTCTCTTGAACCTTTACACTATT
TCGTATTTTCTCGGTTTTAGCCGCCCACTTTTCACGCGTTAACAGGGTAAGCTATATCAG
ATGTGACTTTTCTTTTTCACTCATCTAATGTTGTTTTTCGCGTCACATTTTTTGCCAATA
AATAAATACATCACAATGTTCTATATTGTATATTCAATGGAAGTCATTAGGTTATTGGGC
AAGATTTCAAGGAGGTAGCATACTGGTAAATATACGATCC
Chr coordinates
Chr VIII from 402966-406178