Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
MNL1 Systematic Name
YHR204W Alias
HTM1 Strain
S288c Description
Alpha-1,2-specific exomannosidase of the endoplasmic reticulum; involved in glycan trimming of both folded and misfolded glycoproteins; complexes with Pdi1p, and trims a mannose from Man8GlcNac2 glycans to generate Man7GlcNac2, an oligosaccharide signal on glycoproteins destined for ER-associated protein degradation; requires Pdi1p for stability and substrate recognition; human homolog EDEM1 can complement yeast null mutant External sources
Open in SGD
Open in KEGG
Gene Sequence
Download FASTA View Seq
Sequence hidden Promoter Sequence
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>MNL1 YHR204W
TTACTTAACAAGGATAAAGTTTCTCATCAGAATTCTATCTTCCAGATAGATAAACACAAC
TCTTATATTCTTTCTTTAGTCCGCATCGTCACTTTGGTGCAAATCACTTGTACCAATCAT
GAGAGGGTACCCATCTTCAAAGAAAACTATTATCTTGTTTTGCCAACTCTTCATTTTTTT
AGGTGGAAATCAACATACGGTCCTCTAGCCATCTTTCCTCAATAGTGGTGTATCTATTGT
TATACTTAGTCGACGTTATATGAAAAAGAAACTATTCTAAATCTTACAATATCACTACTA
TTAACTCTACCGATAATAAAACAAAGCGACTTGAAGCAGCTCCAAATCCTAGAGAAGGAA
GATACGATGCCATTGCGCTAACGAAACCACATGGATCCTCCACACAACCACTTAGTTTGG
CAAATCCCAAGACCAAGAGGAACTTTCCTCACCATTCGGGGCAGGTGACGAAGCAAGAGC
GAAGCTGGATTCTACGCTGGATTAGTGAAGCGCCAGCGAGGAATGCTAGAAAGACCAGCC
CAGGAACAATAGAAAATTACGCGGTAGGATAATCTCCTTGACGGAAAAACGCTGTGTGAC
ACTGACTAGCCTGAAAAAATAGAAAAAAAGGAGATGCGCCCTGCAAAAAGCGCAATAACG
CGCACACAAAATGTCTGGGTGAAATGTATGGATGCATAATTGTCTCGAAAATAATTGTTT
AAAGAGAATAACCATAAAACAGGCTGAAAAGCAAGCACTGCTCAATGTTAGTTTCACTGG
CGACTCTATCTCACCATGGTTACACTATTAGTACATTTGGTATAGACTGATAGGTTTCCG
TTGTGCTTTAACGACGGGTAACGATTTATTTCTGGCGTGTTTCAGCGACTATTAATAATA
AGCAATAAAGAAGGACGCGTTTTTGAATATGTATTAATGGGTCAAGAGTAACCATGATAA
TTTCATATTTCCATGGATTGGTTACATTCAGGGAAATAGA
Chr coordinates
Chr VIII from 506319-508709
