Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
MNL1 Systematic Name
YHR204W Alias
HTM1 Strain
S288c Description
Alpha-1,2-specific exomannosidase of the endoplasmic reticulum; involved in glycan trimming of both folded and misfolded glycoproteins; complexes with Pdi1p, and trims a mannose from Man8GlcNac2 glycans to generate Man7GlcNac2, an oligosaccharide signal on glycoproteins destined for ER-associated protein degradation; requires Pdi1p for stability and substrate recognition; human homolog EDEM1 can complement yeast null mutant External sources
Open in SGD
Open in KEGG
Gene Sequence
Download FASTA Hide Seq
>MNL1 YHR204W
ATGGTTTGCTGCTTATGGGTGCTTCTAGCATTGTTGCTTCATCTCGATCATGTAGCATGC
GAAGACGATGCGTACTCATTCACTTCTAAAGAACTTAAGGCTTACAAGCAGGAAGTGAAG
GAGCTGTTTTATTTCGGCTTCGACAATTATTTAGAGCATGGGTATCCATATGATGAGGTA
AAACCCATTTCATGCGTTCCTAAGAAGAGAAACTTTGAAGATCCTACTGATCAAGGCACC
AACGATATATTGGGCAATTTTACAATCACTTTAATAGATTCTTTAACCACTATTGCTATA
CTGGAAGACCGGCCGCAGTTTTTGAAAGCTGTTCGACTTGTTGAAAGGACATTTCCTGAT
GGCAATTTCGATATTGATTCCACAATACAAGTTTTTGAAATTACTATACGTGTTATCGGA
TCACTACTATCATCACATCTTTATGCTACGGATCCCACAAAGGCAGTGTATTTAGGGGAC
GATTATGATGGCTCACTGTTACGTCTCGCCCAGAATATGGCAGATAGGCTCTTACCTGCA
TATTTAACGTCTACCGGATTACCTATGCCACGGAGAAACATCAAACGAAAATGGGATGTC
TCTGAATTTCCAGAATTTTTGGAGACAGAGAATAATGTGGCCGCTATGGCGTCTCCCATG
TTCGAATTCACTATTTTATCTTACTTGACAGGCGATCCCAAGTATGAGAAAGTTACCAGA
TACGCATTTGATAAAACATGGTCTCTTAGAACTGGTTTGGATTTGCTACCCATGTCCTTT
CACCCCGAAAAACTAACACCATATACGCCCATGACTGGAATCGGCGCCTCCATCGACTCC
CTTTTCGAATACGCTTTGAAAGGTGCTATTTTATTTGATGATTCAGAATTAATGGAAGTT
TGGAACGTAGCATACGAGGCATTAAAGACTAACTGTAAAAACGATTGGTTTTTTGCTAAT
GTAATGGCTGACACAGGGCATTTGTTTGTTCCCTGGATTGATTCTTTGAGTGCTTTTTTC
TCCGGTTTACAGGTGCTTGCTGGTGATTTGGATGATGCCATAGCGAACCATTTAATGTTT
TTAAAAATGTGGAACACCTTTGGCGGTATTCCTGAAAGGTGGAACTTTAGTCCTCCGGAG
TTTCCCCCACTATCTCCATTAGAGCGATCGGGAGCTGTTGCTTTGGATAATATCCTCCCC
TTAGAATGGTACCCATTAAGACCGGAATTTTTTGAGTCAACCTATTTCTTATATAGAGCT
ACAAAAGACCCGTTTTACTTAAATATTGGGGTACATCTGCTAAAAGACCTCAAGCAACGA
TTTAAGTCTAACTGCGGATTTGCAGGTTTCCAAAATGTAATCACGGGCGAACTGCAAGAT
AGAATGGAAACATTTGTGTTGAGTGAAACTTTGAAATACCTGTATTTATTATTTGATGAA
GAGAACGAATTACATAACAGCGCTAGTGACGTAATTTTCAGTACAGAAGCCCATCCAATG
TGGTTGCCCCAAGAAGTGAGGTCCAACTATAAACGTAACGCTAAATTTAACAACTCTGTC
TACTCGTCGCACTTGGAAATTTGCCAGAAAAAGGACAGGGAACAAGCTGGAGAGAACACA
TTGAGCCAAAGAATTGTGGGGTTCGCCAAATCGATCTTTCATAAAGGTCCACCAGACGAA
GAGGCTACTGATCCAATTATAGACTATACCATTGATACTGAACTTCCCGGTACATGCTCT
ATAAAGCCTCATCATGTAATTGGTGACGAATTTTGGTATTCTCCAATGTTGAGCAATTTT
GACAGATTATTCGAGATTGACTCCCGGTTCGCTGCCACGCTAATTAAACCTTCACACATG
CATAACTATAATGCAATTGAACTAGAACCTGGATTTTATAACAGGTGGTCCAATCCGCAA
TTTAGCACGTGCCTGATCCCACCCACCACCGAAATTTTCGAACTACTATTCGACCTTCCT
GGATATCATCAGTTGAATCCATTAATGTTAGAAAACAAAACTATTACATTTGAAACCTTT
GGAGGTAGGTCAAGGTTGAAGATCGAAAAATTGCAAATCTACCAAATTGATTACTATGGA
GACTTAATCACTGCATCGACATTCCAAGACGTCTCCCGCAAGGATATTTTCTCGAATGCA
TGCGATGCAGTGGCAAGCTTGTATTCTCCCACTTATCTTTACAGAGTAGTAGCCATCAAC
GGACGCATATTGCCTCGCCATGGAAGTGTACAAATCAAGAAACATAGTCCTGTGCTCACT
TCCAATGGCACAAGAGAGGAAGACGAATTCAAAATGGATGGCATCGGGATTAATGACCAT
TCCCAACTCATGTTAGAATGCACGCCCATCATCAACTTATTTATTGTATGA Promoter Sequence
Download FASTA
>MNL1 YHR204W
TTACTTAACAAGGATAAAGTTTCTCATCAGAATTCTATCTTCCAGATAGATAAACACAAC
TCTTATATTCTTTCTTTAGTCCGCATCGTCACTTTGGTGCAAATCACTTGTACCAATCAT
GAGAGGGTACCCATCTTCAAAGAAAACTATTATCTTGTTTTGCCAACTCTTCATTTTTTT
AGGTGGAAATCAACATACGGTCCTCTAGCCATCTTTCCTCAATAGTGGTGTATCTATTGT
TATACTTAGTCGACGTTATATGAAAAAGAAACTATTCTAAATCTTACAATATCACTACTA
TTAACTCTACCGATAATAAAACAAAGCGACTTGAAGCAGCTCCAAATCCTAGAGAAGGAA
GATACGATGCCATTGCGCTAACGAAACCACATGGATCCTCCACACAACCACTTAGTTTGG
CAAATCCCAAGACCAAGAGGAACTTTCCTCACCATTCGGGGCAGGTGACGAAGCAAGAGC
GAAGCTGGATTCTACGCTGGATTAGTGAAGCGCCAGCGAGGAATGCTAGAAAGACCAGCC
CAGGAACAATAGAAAATTACGCGGTAGGATAATCTCCTTGACGGAAAAACGCTGTGTGAC
ACTGACTAGCCTGAAAAAATAGAAAAAAAGGAGATGCGCCCTGCAAAAAGCGCAATAACG
CGCACACAAAATGTCTGGGTGAAATGTATGGATGCATAATTGTCTCGAAAATAATTGTTT
AAAGAGAATAACCATAAAACAGGCTGAAAAGCAAGCACTGCTCAATGTTAGTTTCACTGG
CGACTCTATCTCACCATGGTTACACTATTAGTACATTTGGTATAGACTGATAGGTTTCCG
TTGTGCTTTAACGACGGGTAACGATTTATTTCTGGCGTGTTTCAGCGACTATTAATAATA
AGCAATAAAGAAGGACGCGTTTTTGAATATGTATTAATGGGTCAAGAGTAACCATGATAA
TTTCATATTTCCATGGATTGGTTACATTCAGGGAAATAGA
Chr coordinates
Chr VIII from 506319-508709
