Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Standard Name
IMD2
Systematic Name
YHR216W
Alias
PUR5
Strain
S288c
Description
Inosine monophosphate dehydrogenase; catalyzes the rate-limiting step in GTP biosynthesis, expression is induced by mycophenolic acid resulting in resistance to the drug, expression is repressed by nutrient limitation; IMD2 has a paralog, YAR073W/YAR075W, that arose from a segmental duplication
External sources
Open in SGD
Open in KEGG
Gene Sequence
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Sequence hidden
Promoter Sequence
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>IMD2 YHR216W
ACTTCCTAAAGGTCTGTAACGTCAGCAGCGTCAGTAACTCTACTGAATTGACCTTTTTCT
GGGACTGGAATACCAAGCACTACAACGACACTTTATTAAAACAGTAAATAGACCTAATAT
GATTTATGTAATTTTAGAAACTAAATATGAATGCTAATTTTTTTCTTATTTTGACTTTTG
CTTGCGAGAAGTACCAAGTTGGAACAACAAACACAGTCCAAAGAGGGAAATACAAAGGCA
CAGTACGCAATTACTTTATTATTCTTTAGCAAGACGAAGATAGTATGAATATACGTGTAA
GGCATATGCAAAGCCATGATTTTATACCATAGACATGACATGCGGGTTACATGAGGTGGT
AAAATGTTTTAAGATAGCGTCCAGGGCAAGTACATGAAATGTCGTTTAGAGATGATGCAA
GAGTAGGGTTATGATGTGAAAGAATAGGGCAATTAATTAACAGAGCGGATGTTGTAGGAT
GATATAGTGACACATAATATATAAATGATCGGTTGAGCGCGATATTATATAAGAACATCC
ATATGAGTATATATCCTACCGTGTCTGTTCTCTACAGTGCTTCTTTTATTCAAAATTATT
GGTTTTCGTAACCGCCGCGCAGGCACGCCGCGCATCTCTTTTTCTCGAAGAAAGCGGAAA
AATAAAAACGAAAAAATAAAAAAAAAAAAAAGTATAAATAGTGAAGACTTTTTCCATTTG
ATATTTGGTAAAAATTTCGGCTGGAAGTTTTTTGCTGAACATTTAACCGGAGAATCTTGG
TGGCTTTTTCTCAGTTTCGTGGGCTTATACATTTTACCTAGTATGCTGGGAACCTTTTTT
TCCGTATTCTATTCTATTCCTTGCCTTACTTTTCTTATTATTTTCTATATAACCAATTTC
AATAATACTTTTTAACTGTCATAAACGCATTTTGTTTATTACAAATTAAAAGAATTAAAT
ATAATCAGTGCAATTAATAACTCCACAAGTAGCAAAAGCA
Chr coordinates
Chr VIII from 554396-555967