Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name IMD2
Systematic Name YHR216W
Alias PUR5
Strain S288c
Description Inosine monophosphate dehydrogenase; catalyzes the rate-limiting step in GTP biosynthesis, expression is induced by mycophenolic acid resulting in resistance to the drug, expression is repressed by nutrient limitation; IMD2 has a paralog, YAR073W/YAR075W, that arose from a segmental duplication
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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>IMD2 YHR216W
ATGGCCGCCATTAGAGACTACAAGACCGCACTAGACTTTACCAAGAGCCTACCAAGACCG
GATGGTTTGTCAGTGCAGGAATTGATGGACTCCAAGATCAGAGGTGGGTTGACTTATAAC
GATTTTTTAATCTTACCAGGTTTAGTCGATTTTGCGTCCTCTGAAGTTAGCCTACAGACC
AAGCTAACCAGGAATATTACTTTAAATATTCCATTAGTTTCCTCTCCAATGGACACGGTG
ACAGAGTCAGAAATGGCCACTTTTATGGCTCTGTTGGGTGGTATCGGTTTCATTCACCAT
AACTGTACCCCAGAGGACCAAGCTGACATGGTCAGAAGAGTCAAGAACTATGAAAATGGG
TTTATTAACAACCCTATAGTGATTTCTCCAACTACGACCGTTGGTGAAGCTAAGAGCATG
AAGGAAAAGTATGGATTTGCAGGCTTCCCTGTCACGACAGATGGAAAGAGAAATGCAAAG
TTGGTGGGTGTCATCACCTCTCGTGATATACAATTCGTTGAGGACAACTCTTTACTCGTT
CAGGATGTCATGACCAAAAACCCTGTTACCGGCGCACAAGGTATCACATTATCAGAAGGT
AACGAAATTCTAAAGAAAATCAAAAAGGGTAGGCTATTGGTTGTTGATGAAAAGGGTAAC
TTAGTTTCTATGCTTTCCCGAACTGATTTAATGAAAAATCAGAACTACCCATTAGCGTCC
AAATCTGCCAACACCAAGCAACTGTTATGTGGTGCTTCTATTGGGACTATGGACGCTGAT
AAAGAAAGACTAAGATTATTGGTAAAAGCTGGGTTGGATGTCGTCATATTGGATTCATCC
CAAGGAAACTCTATCTTCGAATTGAACATGCTCAAGTGGGTCAAAGAGAGTTTCCCAGGT
CTGGAAGTCATCGCTGGTAACGTTGTCACCAGGGAACAAGCTGCCAATTTGATTGCTGCC
GGTGCGGACGGTTTGAGAATTGGTATGGGAACTGGCTCTATTTGTATTACCCAAGAAGTT
ATGGCTTGTGGTAGGCCACAAGGTACAGCCGTCTACAATGTGTGTGAATTTGCTAACCAA
TTCGGTGTTCCATGTATGGCTGATGGTGGTGTTCAAAACATTGGTCATATTACCAAAGCT
TTGGCTCTTGGTTCTTCTACTGTTATGATGGGTGGTATGTTGGCCGGTACTACCGAATCA
CCAGGTGAATATTTCTATCAAGATGGTAAAAGATTGAAGGCGTATCGTGGTATGGGCTCC
ATTGACGCCATGCAAAAGACTGGTACCAAAGGTAATGCATCTACCTCCCGTTACTTTTCC
GAATCAGACAGTGTTTTGGTCGCACAAGGTGTCTCCGGTGCTGTCGTTGACAAAGGATCC
ATTAAGAAATTTATTCCATATTTGTACAATGGTTTACAACATTCCTGTCAAGACATCGGC
TGTAGGTCGCTAACTTTATTAAAGAATAATGTTCAAAGGGGTAAAGTTAGATTTGAATTC
AGAACCGCTTCTGCTCAACTAGAAGGTGGCGTTCATAATTTACATTCTTACGAAAAGCGT
TTACATAACTGA
Promoter Sequence
Download FASTA
>IMD2 YHR216W
ACTTCCTAAAGGTCTGTAACGTCAGCAGCGTCAGTAACTCTACTGAATTGACCTTTTTCT
GGGACTGGAATACCAAGCACTACAACGACACTTTATTAAAACAGTAAATAGACCTAATAT
GATTTATGTAATTTTAGAAACTAAATATGAATGCTAATTTTTTTCTTATTTTGACTTTTG
CTTGCGAGAAGTACCAAGTTGGAACAACAAACACAGTCCAAAGAGGGAAATACAAAGGCA
CAGTACGCAATTACTTTATTATTCTTTAGCAAGACGAAGATAGTATGAATATACGTGTAA
GGCATATGCAAAGCCATGATTTTATACCATAGACATGACATGCGGGTTACATGAGGTGGT
AAAATGTTTTAAGATAGCGTCCAGGGCAAGTACATGAAATGTCGTTTAGAGATGATGCAA
GAGTAGGGTTATGATGTGAAAGAATAGGGCAATTAATTAACAGAGCGGATGTTGTAGGAT
GATATAGTGACACATAATATATAAATGATCGGTTGAGCGCGATATTATATAAGAACATCC
ATATGAGTATATATCCTACCGTGTCTGTTCTCTACAGTGCTTCTTTTATTCAAAATTATT
GGTTTTCGTAACCGCCGCGCAGGCACGCCGCGCATCTCTTTTTCTCGAAGAAAGCGGAAA
AATAAAAACGAAAAAATAAAAAAAAAAAAAAGTATAAATAGTGAAGACTTTTTCCATTTG
ATATTTGGTAAAAATTTCGGCTGGAAGTTTTTTGCTGAACATTTAACCGGAGAATCTTGG
TGGCTTTTTCTCAGTTTCGTGGGCTTATACATTTTACCTAGTATGCTGGGAACCTTTTTT
TCCGTATTCTATTCTATTCCTTGCCTTACTTTTCTTATTATTTTCTATATAACCAATTTC
AATAATACTTTTTAACTGTCATAAACGCATTTTGTTTATTACAAATTAAAAGAATTAAAT
ATAATCAGTGCAATTAATAACTCCACAAGTAGCAAAAGCA
Chr coordinates Chr VIII from 554396-555967
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