S.cerevisiae - Yeastract

Locus Information

Standard Name	SSM4
Systematic Name	YIL030C
Alias	DOA10, KIS3
Strain	S288c
Description	Membrane-embedded ubiquitin-protein ligase and retrotranslocase; ER and inner nuclear membrane localized RING-CH domain E3 ligase involved in ER-associated protein degradation (ERAD); aids Cdc48p in the extraction of faulty membrane proteins; targets misfolded cytosolic/nucleoplasmic domains of soluble and membrane embedded proteins (ERAD-C) and Sbh2p, a transmembrane domain-containing substrate (ERAD-M); C-terminal element, conserved in human ortholog MARCH6, determines substrate selectivity
External sources	Open in SGD Open in KEGG

Gene Sequence Download FASTA View Seq	Sequence hidden
Promoter Sequence Download FASTA	>SSM4 YIL030C CAACTGTAAAAATTGGATGCATTTTTTCCTATTATACCTTTTTCTAACCGCTTCTAACTT AATTGTTCAATTGGCCTATTTTTCAAAAGAAATGTGTAGTCAGGGTATAAACGTTCCTGG AACGAAGAAACCAGGTAATAGAGTTTATTTATCGGTTATCATACTAATGGGGAACGGGTG ATAGAACTTTTACCAATGAAAAGAAATCAGCAGGCCATAATTTGGCTTTATTAAAATTAA TAACATTATGGTGCTGTTGCGTTTATTAAAACAGACTAAAGCTGTTGGAATGAAATTCTA ATGTTATCTATTTAGTAGTAATAGCATCACATGCGGTGTAAGAGGATGGCGTAAATTATG AGAAGCTGTCATCGAGGTTAGAGGAAGCTGAAATACAAAAATTGATAATGTAATAGGAGA ATGAAACATATAAAACGGAATGAGGAATAATCGTAATATTAGTATATAGAAATATAGATT CCATTATGAGGATTCCTAGATCCTCGAGGAGAACTTCTAGTATATTCCGTATACATAATA TTATAAGCCTTTATCAACAATGGAACCCCCAACAATTATCTCAAAATTCACCCATATCTT AATTAGTAACATGAATAGTACTAAACAGATGATATTTTAAAGTTTCATTCCAACAAGCAT CTTAAATGTGCTATTACTTCCTAAAATAAGTAGTTTTTCCAACGAAATAGCCTTGTTGGC GCAATCGGTAGCGCGTATGACTCTTAATCATAAGGTTAGGGGTTCGAGCCCCCTACAGGG CTATCTTTTTACCATTTTCAATTCAATAGAAAAATTAAATCATTAGAGACGGAAAACTGG TTGAAAACGCATCGATTGAGGACATTGAAAAGATGATTATGACCGATCTATGAAGCCATA AGATTACGTTAAGAATAGTTCTTTGTTACTGATTTCAAAAACTGTTTTTTTAGCCAAGAG TACCACTAATTGAATCAAAGAGACTAGAAGTGTGAAAGTC
Chr coordinates	Chr IX from 300009-296050