Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
APQ12
Systematic Name
YIL040W
Strain
S288c
Description
Nuclear envelope/ER integral membrane protein; interacts and functions with Brr6p and Brl1p in lipid homeostasis; mutants are defective in nuclear pore complex biogenesis, nuclear envelope morphology, mRNA export from the nucleus and are sensitive to sterol biosynthesis inhibitors and membrane fluidizing agents; exhibits synthetic lethal genetic interactions with genes involved in lipid metabolism
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>APQ12 YIL040W
ATGGACGCTACTCAACCGCAATACGAACTATCCGTAGTAACACAATGCCTAAAGTCTGCC
ATTGACGTCATCCAATGGTTGATTCCTACTATTACTAAGTTCAGCCAATCACACCCGTTA
GTTTTCCAACTATTGTTTATTTTCTTCACATTTTATGTCTTTTACAAGTTGTTGATGAAC
TTCATTACTCTGGTCAAAAGATTCCTGTATTTGACGTTGGTAGTAACATGTATCGGTATT
TATATGCGTGGTTCGCAGCAGTTTTTGACTGTGGACCTGTTGAATTTCTACAATTTCGTC
ATGTCAAATAGATACTACGCATTTAAAATTTATACTCTGTTTATTAATGCCCTGGAAAGA
GAAATCAACACTGTTTATCATTTGGCGCAGATGAAAATGGAACAGTTGCTTAAATAG
Promoter Sequence
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>APQ12 YIL040W
AAACTGATTTACAACCACTTCTTGGGTGTAACTGCTATCTACGAAAACGGATCGTACGAT
TACCCTAAATACATCAACGAATCCGTCAACGAGTTTTCAAGAAGCGTGGCTTCCAAGTTG
ACAGAGTTGACTCATGCTACATCTGCGTCTGAGGCACAAAACATCTTAGTTGCTCCAGGC
CCCATCAAAGAACCCAAGACGTTGAACTACGCCCTCAGTAAAGTGGCTTTGAACTCCAGT
GAATGTTTGAACAAGATGTTCCCCACCGAGGAACAACCCTTGGCTTCGGCACTCTTGCAA
TTCAGTGATGTGCAGGCTAAGATTGCTCAAGCTAGAATTCAACAAGATACCTTGATTCAA
ACCAAATTCAATAAAAATTTGAGGGAAAGGCTCTCTTTTGAGATCGGTAAGGCCGATAAG
TGCCGCAAGGATGTCCATTCCATGAGATTAAGATATGACGTGGCAAGAACTAACTTGGCA
AACAACAAGAAGCCAGAAAAGGAAGCTTCCTTGAGAGTCCAAATGGAGACTTTGGAAGAC
CAGTTTGCTCAAGTCACTGAAGACGCTACTGTGTGCTTGCAGGAGGTTATTTCTCACGCT
AACTTCAGTGAAGATTTGAAGGAATTGGCCAAGGCTCAAGCTGAGTATTTTGAAACCTCG
GCTGGCCTAATGAAAGAGTTCCTATCCAACTCATTTGCGGAAGAGCCGGAAGCAAAGCCT
GAGGTTGCAGAAGAAGAAAAGCCACAGACAGCTATCTCTATGAATGACGAAGACGACGCT
TAATAGCCGCCCTGTTCTTGTCTTTCTCTCTCCTTCTCTATATATATATATTTACTTAAT
ACAATATCATATTCTCTAGTGTCGTACGAATATTATCATTTATTTGCTGGCTTTTGTAGT
GAGTATATTTTTTGTAGAGAAAATATAATTACTGGAAGAGAAAAAGCTACTGAAAAAAAT
TTCGTAACAGTCACCAAAGGGCAAAGTGAGCAACCCAAAA
Chr coordinates
Chr IX from 277723-278139