Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Standard Name
HYR1
Systematic Name
YIR037W
Alias
GPX3, ORP1
Strain
S288c
Description
Glutathione peroxidase; functions as hydroperoxide receptor to sense intracellular hydroperoxide levels and transduce redox signal to Yap1p transcription factor; glutathione peroxidase activity is neuroprotective in models of Huntington's disease; HYR1 has a paralog, GPX1, that arose from the whole genome duplication
External sources
Open in SGD
Open in KEGG
Gene Sequence
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Sequence hidden
Promoter Sequence
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>HYR1 YIR037W
CAAAGAGTCGGGAATACCTTTCAGGACGAGTTGCGCTAGTACCGCCGCAGGCACCTTTGG
GTCCAGCAGTGACGAAGTCTTGTACAATTGAGTAAACCTCTCGAGAGCCTTGGGTGTCAT
GCCCTGAGGACCCAATGTTTCCCTAATATCTTTCTGCATCTGCGTGTCAACGACGCCCGG
TGCAATACACACGGCACGCACTTTATCACTGGGCTCTTCACTGGCAATGTCCATGGCAAA
GTGGTTTAATGCGGCTTTCGAGCAGCCGTACGCCGACCATCCGTTATATGGTTTCACACT
GGCTCCAGAGCTGACGAAGACAATGTTGCCTACAAATGGCGAGCTCTTCAAGAGGGGTAA
ACACAGTGCCACCAAAGAGACAATGCTGAAAAAGTTCACATCGAACAGCCGTTCCCACTG
CTTGATGTCGTGTTCGGAGTTGGACTGGGAGATGGACTTCACCGGTTCTAGCATCCCCGC
ATTTGCGACAATACCGTCCAGTTTTCCATGCTTTTGCCGGATTTCCTCCACCAACGCTTC
CATTCGAGACCTGTCCGTGATGTCGAGGACACGATAGACAAATTTGTCTGCACCGTATTC
TCTTTGCAAAGACTGCAGACCAGCTTCCGTTCTTGCTACGCCGTAGACGATGCATTCATC
GTCCTCTTCGATAACAGTTTTCACCAATTGCAGGCCAATCCCACGGGAGGCACCTGTAAT
CAAAATAACCTTGCCCATATCCCTTCTTTGACAGATTATAAGTTGTTTCTCTTGTTGCTG
TTCGCGACAGCCCTTATTTCCTGTATTCCTTCTTCTTTTTCTGCATTATCGTTTTTAGCC
ACTTTACGAAAAAGGTCAAAAAGTGAAAAAAAGAGGGAAAAAACCATGAGGAACAGTATG
CTCCCTTAATATCGGAAAAGCAATAGTAATAAAAACAGCATCAGAGCTTTCCACGTCTCT
CTCTTCCAAGCTGTCATCTCGTAAAGTATTCAAGTTTATC
Chr coordinates
Chr IX from 423128-423619