Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name HYR1
Systematic Name YIR037W
Alias GPX3, ORP1
Strain S288c
Description Glutathione peroxidase; functions as hydroperoxide receptor to sense intracellular hydroperoxide levels and transduce redox signal to Yap1p transcription factor; glutathione peroxidase activity is neuroprotective in models of Huntington's disease; HYR1 has a paralog, GPX1, that arose from the whole genome duplication
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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>HYR1 YIR037W
ATGTCAGAATTCTATAAGCTAGCACCTGTTGACAAGAAAGGCCAACCATTCCCCTTCGAC
CAATTAAAGGGAAAAGTGGTGCTTATCGTTAATGTTGCCTCCAAATGTGGATTCACTCCT
CAATACAAAGAACTAGAGGCCTTGTACAAACGTTATAAGGACGAAGGATTTACCATCATC
GGGTTCCCATGCAACCAGTTTGGCCACCAAGAACCTGGCTCTGATGAAGAAATTGCCCAG
TTCTGCCAACTGAACTATGGCGTGACTTTCCCCATTATGAAAAAAATTGACGTTAATGGT
GGCAATGAGGACCCTGTTTACAAGTTTTTGAAGAGCCAAAAATCCGGTATGTTGGGCTTG
AGAGGTATCAAATGGAATTTTGAAAAATTCTTAGTCGATAAAAAGGGTAAAGTGTACGAA
AGATACTCTTCACTAACCAAACCTTCTTCGTTGTCCGAAACCATCGAAGAACTTTTGAAA
GAGGTGGAATAG
Promoter Sequence
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>HYR1 YIR037W
CAAAGAGTCGGGAATACCTTTCAGGACGAGTTGCGCTAGTACCGCCGCAGGCACCTTTGG
GTCCAGCAGTGACGAAGTCTTGTACAATTGAGTAAACCTCTCGAGAGCCTTGGGTGTCAT
GCCCTGAGGACCCAATGTTTCCCTAATATCTTTCTGCATCTGCGTGTCAACGACGCCCGG
TGCAATACACACGGCACGCACTTTATCACTGGGCTCTTCACTGGCAATGTCCATGGCAAA
GTGGTTTAATGCGGCTTTCGAGCAGCCGTACGCCGACCATCCGTTATATGGTTTCACACT
GGCTCCAGAGCTGACGAAGACAATGTTGCCTACAAATGGCGAGCTCTTCAAGAGGGGTAA
ACACAGTGCCACCAAAGAGACAATGCTGAAAAAGTTCACATCGAACAGCCGTTCCCACTG
CTTGATGTCGTGTTCGGAGTTGGACTGGGAGATGGACTTCACCGGTTCTAGCATCCCCGC
ATTTGCGACAATACCGTCCAGTTTTCCATGCTTTTGCCGGATTTCCTCCACCAACGCTTC
CATTCGAGACCTGTCCGTGATGTCGAGGACACGATAGACAAATTTGTCTGCACCGTATTC
TCTTTGCAAAGACTGCAGACCAGCTTCCGTTCTTGCTACGCCGTAGACGATGCATTCATC
GTCCTCTTCGATAACAGTTTTCACCAATTGCAGGCCAATCCCACGGGAGGCACCTGTAAT
CAAAATAACCTTGCCCATATCCCTTCTTTGACAGATTATAAGTTGTTTCTCTTGTTGCTG
TTCGCGACAGCCCTTATTTCCTGTATTCCTTCTTCTTTTTCTGCATTATCGTTTTTAGCC
ACTTTACGAAAAAGGTCAAAAAGTGAAAAAAAGAGGGAAAAAACCATGAGGAACAGTATG
CTCCCTTAATATCGGAAAAGCAATAGTAATAAAAACAGCATCAGAGCTTTCCACGTCTCT
CTCTTCCAAGCTGTCATCTCGTAAAGTATTCAAGTTTATC
Chr coordinates Chr IX from 423128-423619
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