Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name SRS2
Systematic Name YJL092W
Alias HPR5, RADH, RADH1
Strain S288c
Description DNA helicase and DNA-dependent ATPase; role in DNA repair and checkpoint recovery, in the proper timing of commitment to meiotic recombination and the Meiosis I to II transition; blocks trinucleotide repeat expansion; affects genome stability; disassembles Rad51p nucleoprotein filaments during meiotic recombination; stimulates Mus81p-Mms4p endonuclease activity independent of catalytic activity; ATPase and ssDNA translocating motor activities inhibited by Dmc1p; functional homolog of human RTEL1
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
Download FASTA
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>SRS2 YJL092W
ATGTCGTCGAACAATGATCTTTGGTTGCATTTAGTATCCCAGTTAAATACTCAACAGAGA
GCAGCGGCCCTCTTTGATTACACTAGAGGGCTGCAGGTCATTGCCGGTCCCGGCACAGGG
AAGACTAAGGTTTTAACTTCAAGAGTAGCGTATCTTATTCTGCACCACCATATTCATCCC
CGCGATATTATAGTGACTACTTTCACTAACAAAGCTGCTAACGAAATGAAAGAGCGTTTG
CAAGAAATGTTACGCGGGGCAGGCGTGAATATTTCGGAGCTCTTAATTGGTACTTTTCAT
AGTATTTGCCTGAAAATACTTTATAGATTTGGCCACTTGGTGGATCTACAGAAAGACTGG
AGAATTATTGATGAGAAGGAAATAGATGTCATTTTAGATGATATGATCGAAAAAGTTCCC
GACCAAATAAGGGATTATGCTTCCTCAATCACAAGGAAAGTAAATCTTTGTATGCCGAGT
AAAAATGGAGATGAATGGACTATTCATCCGAAGCTGATCAAGAAACAGATATCAAAGCTA
AAATCAAACGCAATATTACCTGAGGAATACATCTTAGATTCGAATCATGACGCCGCGCTT
GGTTACTTTTACCAAATATACCAATCAGAGCTAAGCAAGAAAAATACGTTAGATTTTGAT
GACTTATTAATGTACACCTTTCGTTTGCTGACTAGAGTGCGTGTTTTATCCAACATAAAG
CATGTTTTAGTTGACGAATTTCAAGATACTAACGGCATTCAATTGGACTTGATGTTTCTT
TTTGCTAAGGGAAATCATCATCTTTCGAGGGGGATGACCATCGTAGGTGATCCTGATCAA
AGCATATATGCTTTCAGAAACGCCTTAGCGCACAACTTTCTAGAAATGGGCAGAAAATGT
CCCATCGAGTACTCAACTATCATACTTGTTGAAAATTATCGTTCATCACAAAAAATTCTA
AATACAAGCGAAATTTTAATAACGCAACAAAACAAAGGTCGGCAGAATAGGGCTCCACTC
CGTGCCCAATTTGACCTGGATTTTCCACCAGTTTACATGAATTTCCCCGCTTACTTTTTG
GAAGCACCTTCTTTAGTTCGGGAACTACTATATTTGAAGGCATTGCCAAACCTATTCACA
TTTAATGACTTTGCTATCCTAGTAAGACAACGAAGACAAATTAAAAGGATCGAAAGTGCA
TTAATAGAACATCGGATACCCTATAAAATTATTAGGGGCCACAGTTTCTGGGATTCCAAG
GAAACAAGAGCGATGTTAAATTTATTAAAATTGATATTTTCTCCGAATGACAAACATGCA
ATTCTTGCTTCACTTTTATATCCAGCAAGGGGCCTTGGTCCTGCTACCGGTGAGAAGATT
AAGAACGCATTGGACACGTTAGCTACCGATGTGTCATGTTTCCAAATATTGAAAGACATA
AGTAGTAAAAAAATAATGCTAGACATACCGACGAAAGGCCGTTCTGTGATTGCTGACTTC
ATTTCAATGATAGAAAATTGTCAATTGTTGCTCCAGAGCACTTTACTAGGGGGTCTTTCA
GATTTATTTGATAAGCTATATGAATTATCAGGTCTGAAATACGAATACTTGTACAAGGAT
GGTAAGAAAAAAAATGATCAGCTTGAAAAATCCGAACCTAATTTATTAAACGCAAGACAT
AAGAATATTGAACTTTTGAAAAACTATTTCCTGGCTCTTCTTTCCAAGTCAGAATCTTCA
GATAAAGAAAAAAATGAAGCCATTAAAGCAGCAACAGATGAAGCCGAACCAATAGAGAAC
AAGGTCATCACTCCAAAAGAATACCTCCGTAATTTCTTCAATTCACTTTCCCTTCATTCT
GATGCAGCTGAGGAGGAAGAGTCGGAATCCAATAAAGATGCAAAAATAAAACGTGAGAAG
AATGGGTTTGTCACGATATCTACAATTCACGGTGCCAAAGGTCTTGAGTGGCCGGTAGTT
TTTATTCCTGGATGCGAAGAAGGTATAATTCCTTGTGTGTTCAACGATGATAAGAAAGAC
GAATCAGAGGAGGACGAAGAAGAAGATCAAGAAAATAGTAAGAAAGATGCAAGCCCAAAA
AAGACTAGAGTTTTATCCGTGGAAGATTCTATAGATGAGGAAAGAAGAATGTTTTTTGTT
GCACAGACTCGTGCAAAATACCTGTTGTACCTATCAAATACTGTAACTGTGGAAGATGTC
GATAGACCAAGAATTGCAAGCCGATTTTTGACTACTGACTTGATAAAAGCCATGTCCGAT
AGCCAAAAATTATTTGAAAGTACGAATAGTATCAAAAAACTATACCGAATTTTGAACAAA
AAGCCGCCTGCTGAAGATGATAAACTATTCTCCCTTGACCAATTGCGCAAAGACTATAAC
CAATTCATTGAAAATAGGAGAGAAAGGATGATTTGGCAAGGGATACAAATGAATGATGTC
TATGGAATACAGTTGTCTAGAAATAAATTATTGGGTTCTGTTAGTGATTTCACGTCAGCT
GCGGACCAGTTACGACTCGAAACGCAAAACTCTATATTCCCACAGAAGAAACTTATTGAA
AAATCACGCCCATCCAAAATCAATGGCAATTACGCTCCTAAAAGTAGAGTTAAAAGTCCA
GAAAAAAGGTACGCTCCAGAAACTACATCATTCCATTCTCCTACAAAGAAAAAGGTGTAT
GCACCTCAATACGTTTCAACAACTAATGTACCTAGTAGGCAGGAGTTTCATTCTTCTACT
GGGAAAAATATTCCTTTTCTGAGAAGAGAAGATAGGTCCATCACAGACATATCACCACGA
TCATCAACGAGGTCGTTAAAAGGAGCATCTCCAAATAAGACGAGCCACATGTCAGATGAT
TTAATGAGACCATCACCTACGAGGAAGGACAAAGTTACTCGTAATATTCATTTCGCAACT
GCAGGAACTTTCAGAATAGAAACCCAGTCAAATGTTGATGAACTGCATCCTCCGGAATAC
TCCAATAAATCAGGGCAGTCGCTTACGTCGAGTGAATTTTCTGGGTTTTCTAGCGCGTGC
AGTAATTCTGATCAGCCAACGAACTTAATAGAAGATATAAACAACGAATTAGATCTATCC
GATGAGGAGTTATTAAATGACATATCAATAGAAAGGAGGAGAGAGCTTTTGGGCTCGAAA
AAGACGAAAAAAATAAAACCAAAAACTCGAAATAGAAAGTCTAAGAGAGGTGACAAGGTT
AAGGTGGAGGAAGTGATAGATTTGAAGAGTGAATTTGAGGAAGATGACAGCAGAAATACA
ACAGCTGCTGAGTTATTACATAATCCGGATGACACTACAGTTGACAATCGTCCAATAATC
TCCAATGCTAAGTTTTTGGCTGACGCAGCAATGAAAAAGACACAGAAATTTTCCAAAAAG
GTGAAGAATGAACCTGCATCAAGTCAAATGGATATATTTTCTCAGCTGTCACGTGCGAAA
AAAAAGTCAAAATTAAACAACGGTGAAATCATAGTCATCGATTAG
Promoter Sequence
Download FASTA
>SRS2 YJL092W
CTTTACTTGATTCATCAAAACATCGGTGTCATTGCTTCGTGGATTTGTCACCACGGAGTT
GTTCTTTAAGGATCTCCATTTTTCAACTACACAGGCTATCGAGATAGTGTTAGCTACGGG
ACCCAAGCAGGCAGTAATCACAGGGAAATAGCATGAAACCACAAACCAAAAGACGAACAG
TGTTGAAGAAGGCTCTGCATTAATAATACTAACTCTTTCGTCCCGGAACCGCAATGCATC
CTTTAGTTCCTCTGCAAGAACACCCTTAGCTTGCTTCGGTGTGTTGTTTGAATGAGAATC
AACAGCCTGAGCTGAGCTCTCTTGCTCCACTGTCGCCATATTGCCATATCCCAGCGTTTG
TTTGGCAAAGCTGTTCATGAACCTTGTCATATATATAGAAATCGGTAAAATAAATACAAG
AAATATGCTTTGTTATACTGCTAGAAAGGAGTGAAGACATCTGCTCACGATCTACGAGAT
GCGGCTATTTTTGATGGAAAAAGATACATAGGGTCAGGCATTTTTGCCATATTGAATAAC
CAAGATGGTACTGAGTACTCAGGTAATGTATATTACATTGAGTACTTCACTTGTATACAC
AACCACTGCTTCGTATTGTATATCAAGTATCTAACTGTTGATAAACTACAACTTTCTCTT
CAACCATAATGATAGCGCCGCTTAAAACATGCTAGGGTAACGAGACGCGAATGCGAAAAA
CTCCCAAAAAAACCAAAACAAACAAAAGTGACAACAATTAGAACGATGCTGAAGAAGAAT
AGGAGCGAGTTTAGAGTTACCTCCAGCTATCCTGATACTACTGCTTAGGCTACCTTCGCA
GAGTCTCGATAAATTTGCAGTCGGCAAGATAAGAATATTTCTCTACAGCTTTTAGACAGC
TTCCTGTCCCTCTAGTTTCTTTTGCCATCCATAATTGTACTCTGCACTTTGAGTATCATT
CCAATTTGATCTTTCTTCTACCGGTACTTAGGGATAGCAA
Chr coordinates Chr X from 257423-260947
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