Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
LSM1
Systematic Name
YJL124C
Alias
SPB8
Strain
S288c
Description
Lsm (Like Sm) protein; forms heteroheptameric complex (with Lsm2p, Lsm3p, Lsm4p, Lsm5p, Lsm6p, and Lsm7p) involved in degradation of cytoplasmic mRNAs; also enters the nucleus and positively regulates transcription initiation; unlike most Sm-like proteins, Lsm1p requires both its SM-domain and C-terminal domain for RNA-binding; binds to mRNAs under glucose starvation, most often in the 3' UTR; forms cytoplasmic foci upon DNA replication stress
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>LSM1 YJL124C
ATGTCTGCAAATAGCAAGGACAGAAATCAGTCCAATCAGGATGCGAAGCGACAACAGCAG
AATTTCCCAAAGAAGATTTCAGAAGGTGAGGCCGATTTATATCTCGACCAGTATAACTTC
ACTACCACCGCTGCTATTGTAAGCTCAGTAGACCGTAAAATCTTCGTTCTTTTGCGTGAT
GGAAGAATGCTATTCGGTGTACTAAGAACCTTTGACCAATATGCAAATTTGATACTTCAA
GATTGCGTGGAGAGAATATATTTTAGCGAAGAAAACAAATACGCTGAAGAAGACCGCGGC
ATATTCATGATTCGTGGTGAAAATGTTGTCATGTTAGGCGAAGTAGACATCGATAAAGAA
GATCAACCCCTTGAGGCCATGGAACGCATACCATTTAAGGAGGCTTGGCTGACCAAGCAA
AAAAATGATGAGAAAAGGTTTAAAGAGGAAACCCACAAAGGTAAAAAAATGGCCCGCCAT
GGTATCGTTTACGATTTCCATAAATCTGACATGTACTAA
Promoter Sequence
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>LSM1 YJL124C
CACCTGTGGAAAAAAAGCCTTCAGTTGCAGACGGTGAGTTAGGCAACTCTAAAAAAAAAT
TACAGTTTAATCTATTCGACGGCAAGGTAACAGACGGTGAGAAACTGGCATTTGCAAACC
TGGAAAATGCAGTCAAACTCTTCAATACTGCACATGAGGAATACCAGAAACAACAGAAAG
AGGCTGATGCCACTCCAGATGACGATAGGAGTTCTATTAGCAGTAACAGCAATAAAATCA
GTGATTTATTCATATCCATCTTACCAATTGCCATTCCGCAAAAACAAAAAGATGCCGACG
GTGACTTTCAAGTGACCGACTCCAATACGCCAGGCAATTTCAATTTCACCCTTGTATTGA
AAGACATAACTAACGATATTACCACCATAACAAGATCACAAGGATTCCCTGTCAAATGGG
TCAATTGGCTAGAAGGATCCGTGGAGAAAACAGGATCAACAGCAAGTGAGGAGAGGAATA
AGTCATACGATCAAAAGAAACAAAAAGAAAGTGAAGACGAAGACGAAGACGATGAGATCA
TTGATCCTAGTGAATGGGTAAAGGAATGGATCGAAGATGGATTAAGCTTGTCATTTGGGG
TCATGGCACAGAATTATGTCATTGACCGTATGGGTCTTTGATACACTTAATACATAACAT
TTATAGCGTAACGATGATGTATAAAGTTACAAGCGCAGAGGAGTGGGTTCAAATTCGGCC
GACTTGTTACCCGCGTTCGTTGAATAATGGAAAATATGAAAAAAATAGAGGAAGTCGTGA
ATATACAACGGTGTTCAGCACCTGTATTTCAATCTAGGGGAAGCCTGTATGACCAAGGGC
TGATTAAATATTAGTGAAGATACAAGTAACACAGTTTAGTTATATTTTCTTTTCCTTTTC
AACAGGATTGCCAACGCTGCAGTAGAGTTATACCAACATTTGCTCCGCTTTCAAAACCTA
TAAAAGAAAGCAGCCCTCGAATCGAATTAATTCACCAAAA
Chr coordinates
Chr X from 187644-187126