Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name TPK1
Systematic Name YJL164C
Alias PKA1, SRA3
Strain S288c
Description cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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Promoter Sequence
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>TPK1 YJL164C
TCATATCGATACTGGGTATCGGAAGAGGTGTTGTGTTACTGGTCGTATCACCTACATTAC
TGTACACGCTAAAGAGGATTTATCAACACTTGAACCATTCGATAGACAAGATAGACATCT
TTTGCATACAGTTTTCTATGATTGTTATAACACTGAGTCTCTTTGTCATGATACGATTTG
GCGAGAAAACTCCCACATCCATGATAATATTCGCTCTTTTACAGGCATTGAGCGCGTTTT
GTTCACCAACTTTGCAGTCTGGTATCATAAAGTACACCTCTAAGAAACATACAGGCGAGA
TGTTCGGAGCAATGGCTTTGGTAAGGTCCTGTGTTATGCTTGTCATCCCTCCCATCCTCC
TTAAGCTATATGGAAGTACTGTCTCCGTTAATCCTAGTCTGTTTATGTATATACCGTTCT
CAACAAGTATTGTTGCCATCTTGTTGACATTCTTCCTAAGAATTTACAAGAACCCTCCGC
TGGACGGGCCTTAAAAACATTTACATACCGTATACACCACATATTTTTAGTTACTTGTTC
GAAGCTGTGCTGCTATTCGTTCTTGCAAAGCCAGTGTCCTAACGACTTTGCTTATGACAT
GATTCAACATAGTGTTGTTGTGGTTTTTTCTACGTAATCATGATGATCTTTTTTTTCGCG
CTATTAGGGGGGAGGGAAGGCGGGATCTGGTAAAAGTTTGACATAATAATCAAGGGGGAT
ATCGTATCCCTTTACTTGAAAACTTGAAAAATATTCATCTACTATCTCTGGCCAGAAAAA
CGTGAGAATTTTTAGGTGCGAAACATCATAGAAGCTGCGATTGTATCCATCTAAGAGTTT
TAATTTGATAAAGCTAAGGAATCTGACCCTATACTTTTTTTTTTGTTTGGCTTGCTTGCA
TTTTCAATCGGCTTCAAAGGTAGCACAGAAAGTAGTGTTCTCTTAGCTTAAGCAGTGCAT
GAATTATAGCTGATTGTGTGAAAGAATCTTTTTTTTGGGT
Chr coordinates Chr X from 111159-109966
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