Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
SWE1
Systematic Name
YJL187C
Alias
WEE1
Strain
S288c
Description
Protein kinase that regulates the G2/M transition; negative regulator of the Cdc28p kinase; morphogenesis checkpoint kinase; positive regulator of sphingolipid biosynthesis via Orm2p; phosphorylates a tyrosine residue in the N-terminus of Hsp90 in a cell-cycle associated manner, thus modulating the ability of Hsp90 to chaperone a selected clientele; localizes to the nucleus and to the daughter side of the mother-bud neck; homolog of S. pombe Wee1p; potential Cdc28p substrate
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>SWE1 YJL187C
ATGAGTTCTTTGGACGAGGATGAAGAGGACTTCGAAATGCTGGACACGGAGAACCTCCAG
TTTATGGGGAAGAAGATGTTTGGCAAACAGGCCGGCGAAGACGAGAGTGATGATTTTGCT
ATAGGGGGTAGCACCCCGACCAATAAACTGAAATTTTATCCATATTCGAACAACAAATTG
ACAAGAAGTACGGGGACCTTGAACCTGTCATTAAGTAATACAGCTTTGTCAGAGGCTAAC
TCCAAATTTCTTGGGAAAATTGAAGAAGAGGAAGAAGAGGAGGAAGAAGGCAAGGATGAG
GAAAGCGTGGATTCTCGTATTAAAAGGTGGTCTCCGTTCCATGAAAATGAAAGTGTTACT
ACTCCTATTACAAAAAGATCTGCGGAAAAAACGAACAGTCCTATTTCTCTCAAACAATGG
AACCAGCGATGGTTTCCGAAAAATGATGCTCGCACTGAAAATACATCCTCATCCTCTTCA
TATAGCGTCGCTAAACCTAACCAATCAGCCTTTACGTCTTCGGGCCTCGTATCTAAAATG
TCTATGGACACTTCGTTATACCCTGCGAAATTGAGGATACCAGAAACACCAGTGAAAAAA
TCACCCTTAGTGGAGGGAAGAGACCATAAGCATGTCCACCTTTCGAGTTCGAAAAATGCA
TCGTCTTCTCTAAGTGTTTCCCCTTTAAATTTTGTTGAAGACAATAATTTACAAGAAGAC
CTTTTATTTTCAGATTCTCCGTCTTCGAAAGCTTTACCTTCCATCCATGTACCAACCATA
GACTCATCCCCACTGAGCGAGGCAAAATATCATGCACATGATCGTCACAATAACCAGACA
AACATCCTGTCTCCCACTAATAGCTTGGTTACCAACAGCTCTCCACAAACATTGCATTCT
AACAAGTTCAAAAAAATCAAAAGAGCAAGGAATTCGGTTATTTTGAAAAATAGAGAGCTA
ACAAACAGTTTACAACAATTCAAAGATGATTTATACGGCACGGACGAGAATTTCCCACCT
CCAATCATAATATCAAGTCATCATTCAACTAGAAAGAACCCTCAACCTTATCAATTTCGT
GGACGCTATGACAATGACACTGACGAAGAGATCTCCACTCCAACAAGACGAAAATCTATT
ATTGGGGCAACATCTCAAACACATAGAGAAAGCAGACCATTGTCACTCTCCTCTGCCATC
GTGACAAACACAACAAGTGCAGAGACGCATTCCATATCTTCCACCGATTCTTCGCCGTTA
AATTCCAAAAGGCGTCTAATCTCTTCAAATAAGTTATCAGCAAATCCAGATTCCCATCTT
TTCGAAAAATTTACGAATGTGCATTCCATTGGTAAAGGCCAGTTTTCCACGGTCTACCAG
GTTACGTTTGCCCAAACAAACAAAAAGTATGCAATCAAAGCCATTAAACCAAACAAATAT
AATTCCTTGAAACGCATATTACTGGAAATTAAAATACTAAACGAGGTAACAAACCAAATT
ACAATGGATCAAGAAGGGAAGGAATACATCATCGATTACATCAGTTCCTGGAAGTTTCAA
AATTCATACTATATTATGACAGAATTGTGCGAAAATGGTAATTTGGATGGATTTTTACAA
GAGCAAGTTATCGCAAAGAAAAAAAGGTTGGAAGATTGGAGAATTTGGAAAATCATCGTG
GAATTAAGCCTGGCTTTACGATTCATCCATGATTCTTGTCACATTGTGCATCTGGACTTG
AAACCCGCAAACGTCATGATCACATTTGAAGGTAACCTAAAACTAGGTGACTTTGGAATG
GCTACTCATTTACCGTTGGAGGATAAAAGTTTTGAAAATGAAGGTGACAGAGAATATATT
GCACCAGAAATCATTTCTGATTGTACGTACGATTACAAGGCAGATATTTTTTCCCTGGGT
CTGATGATTGTTGAAATTGCAGCGAACGTTGTGTTACCTGACAATGGCAACGCATGGCAT
AAGTTGAGATCGGGTGATTTATCGGATGCAGGAAGATTAAGTTCCACAGATATTCATTCT
GAATCATTATTTTCAGACATTACGAAAGTAGATACAAATGATTTATTTGATTTTGAAAGA
GACAATATCAGTGGTAATAGTAACAACGCTGGCACCTCCACTGTTCATAACAATAGTAAT
ATCAACAACCCTAATATGAATAATGGCAACGATAATAATAATGTCAATACTGCCGCTACC
AAGAATCGTCTTATTTTGCATAAAAGTTCTAAAATTCCCGCATGGGTACCGAAATTTCTT
ATTGATGGTGAATCACTTGAGAGAATAGTACGATGGATGATAGAGCCCAATTATGAGAGA
AGGCCCACGGCAAATCAAATCTTACAAACTGAGGAATGCCTGTATGTAGAAATGACACGC
AATGCAGGTGCTATTATCCAGGAAGACGACTTTGGACCTAAGCCAAAATTTTTTATATGA
Promoter Sequence
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>SWE1 YJL187C
TAACCAACTAGAAGACACATCATTATGCACAGAACAAAAAAATAAAATTAGCACTACTGC
GCTCACGATGACCTGCAGGATTTTTCTCTTCTTTAACCTAATCAGCATTGTAACCTGAAC
TATTAGTATATCCTCTTGTTGTGCTAGGAACCAGTCGTAAAATAAAAATTTCCAATAACC
GTGAAAATGCTTTTTTCATATCTGCGTATATATAAAACACTTTAAAGCCGTGTTGATCCT
TTAGTTGTTACACTTTTTTTTCCCCGCCGATGAGAAAGTGAAAAAAAAAATCCGCAAGAA
CGGGGAAAAAGATAAAAGAAGGCACTTATCTCTCTGAACTCTGCACCGAAACATGCATCT
GTCGTCTATTCCGACTTGGCAACCAAAAGAAGCCCAAGAGCTAGTTGCACTTAAATCAGT
AGAATCGTGAGATTGTTTATTATCTTACTTCTGTTAGAGTGCTTCGCTTTCCATGCATCA
AACTATGGATTTGTGCTGATCTTGCAACCATCGTCCTCTAAGGAAAGAAATGTGGCACCT
TTAAATAGGTTCCACCTCACAGATGCCAACATGTGGGAGATAGGGGGCTATTCGCAATTT
ATTAACGTCTCTAGTACTGGTAAGCCTTTCTAACATTCTTGTGGTCACGTGATGTGTATG
TTTCTTTTTTTTATTCCTCCGGGTGATAACGACGCGAAAAATATTTTTTCATTTTTCTTT
TAACCATCACAATTTGCGACGCGACGCGAAAAAAATGCAGAGAAGTAAAAGAATGCTGGA
TAAGAAATCAACAACACAGTTGAACATTGGCGTGCCCCTGTGTATTAAGTAAAGGTTGTC
CAAGAGGCTCTTTTTTGTATGTATGCGTGTGTTAACTATCCTGCACATCATCTTGCGCAG
TTAGTCCAATAAAAAAAGGATTACTACTGAACAGGTCTTACTATTTTTGATTGCGTAGTG
CTGGGGAAAAGTAAACACACACAGGCGCACACGAGAACAG
Chr coordinates
Chr X from 79262-76803