Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name SOP4
Systematic Name YJL192C
Alias EMC7
Strain S288c
Description ER-membrane protein; subunit of evolutionarily conserved EMC (Endoplasmic Reticulum Membrane Complex) implicated in ERAD (ER-associated degradation) and proper assembly of multi-pass transmembrane (TM) proteins; EMC acts in yeast as an ER-mitochondria tether that interacts with outer membrane protein Tom5 of TOM (Translocase of the Mitochondrial Outer Membrane) complex; suppressor of pma1-7, deletion of SOP4 slows down export of wild-type Pma1p and Pma1-7 from the ER
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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Promoter Sequence
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>SOP4 YJL192C
CCTTACACTTAGCGGCAACATCTTGGGCAGCCAACATAGCAGCGTATGGAGATGATTCGT
CTCTGTCGGCCTTGACTTTCATACCACCAGTAACTCTGGCGATAGTTTCCTTACCAGATA
AATCGGTAACATGTACAAAGGTATCGTTAAAGGAGGCGTAGATTCTGGCAACACCAAAGA
CTTGAGAGTTATCGCGAGCTTGAACAAGGTCTATACATGATAAGAGGTATAGTTGTTAGT
AAACAGAACTTCTGCTTTTTCGATTATTAAAAAATAAACGAATGAGTCACTATCTAACAA
CCATTTAGTTACAATCCTTTTAAGATAAACATTCTTTATTACAGATGATACAGTATTAAG
GGTGAGCGCAGAGCCTCTATAACACAATAGCATTGAAGTGCTTTATTGCAGAAATTTTAA
CTCCGTATTACAGAATTTCATGGCCTTACAAACATAAGTAGCATCTCATAACACTATTGC
AATATAGTTAGGAGTGCTTCAAAGTTGCAAAAAAAATAAAATTCCAATAATAACATCATG
CGCTACCCGATCACAGTCTCCATCTGAAAAAAAGAATAACTAAATGGTTTTAAACAGGAT
ATCACCCCTTTCACGTACCGTTAGCCATTCTTAATTGTTATTGGGAGTTGTTGATTTCAG
TCTTTTTCTCTCTTGCGATGAAGATGCATACAGAAGGAATAGTACCGCTTTTATACTCGT
AGAAGGCAAGTTCTTGCGACTATATCTTTTATTCCGTTTTGTTTTTCAAGTCTATCACCC
ATTAAAAAGTTTGAAATTTTTTCCATATTCTTTTCAGTGTGGTGCAAGGATGTACAATGA
TGTGTTTACACCACATATAAAATCAAGCTCGAAAAACAGTCTCGAAAATGATCGAGGATT
TCAGGATGAAATTATGTATGAAATTAAGATGAACGAATTTGTCAAGCCATTAAATATCAT
CAAAGTAAATTTGATCAACAAGTGAAAGAGCAGTGTGACG
Chr coordinates Chr X from 73414-72710
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