Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name ESS1
Systematic Name YJR017C
Alias PIN1, PTF1
Strain S288c
Description Peptidylprolyl-cis/trans-isomerase (PPIase); specific for phosphorylated S/T residues N-terminal to proline; regulates phosphorylation of RNAPII large subunit (Rpo21p) C-terminal domain (CTD) at Ser7; associates with phospho-Ser5 form of RNAPII in vivo; present along entire coding length of genes; represses initiation of CUTs; required for efficient termination of mRNA transcription, trimethylation of histone H3; human ortholog PIN1 can complement yeast null and ts mutants
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Gene Sequence
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Promoter Sequence
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>ESS1 YJR017C
TGTGCAGAATCTGAGAAACGGTAGAAATTTCATCCATAAGCAGGTTAGTGCTTATCAGCA
CGACAAGTTGATATTTACGTCGATGATCTTATTTGCCGTGCAACGGTCCAAGGAGCACGA
CTCCTTGCAGCACTGGGAGACGATTCCAGGCCTGCAAGGTAAGCAGCCAGACCCTCATCG
TTATGAAGAGGCCACTTCGCTTTTCCAGAAAGAAGTTCTGGACCCACAGAAATTGAGCAG
GTATGCCTCATTGTCCGACAGGTTCCAAGACGCAACCTCGATGAGCAAGTATGTGGATGC
GTTTCAATACGGAGTCATGGAGTACCAATTCCCCAAGGACATGTTCTACTCGGCAAGACA
CACCGACGAGCTGGATTATTTCGTCAAAGTGAGACCTCCCATCACTACCGTGGAGCACGC
GGGCGACGAGTCTTCTTTACACAAGCATCATCCGTACAGGATCCCGAAGAGCATTACTCC
TGAGAACGACGCTCGCTACAACTACGTGGCCTTTGCGTATCTGTCCGATTCCTACCTCCT
ACTCACGATCCCGTACTTCCACAACCTGCCTTTGTACTGCCACAGTTTCAGTGTCTCGCT
CGACCACACGATTTACTTTCACCAGTTGCCTCATGTGAACAATTGGATCTATCTTAAGAT
TTCGAATCCCAGGTCCCACTGGGACAAGCACCTCGTACAGGGCAAGTATTTCGACACACA
GTCGGGACGCATCATGGCAAGCGTCTCTCAGGAGGGCTACGTTGTCTACGGGTCAGAACG
AGACATTCGAGCCAAGTTCTGAGGACAATTCCCTCCCACGTATAAACACATACATATATA
TTCTTATATTATATAATAATATCCTATTTATTATTACATCACCTTTCACGAGCGGGTATC
ATACCTTTTTCCCTTCGATCTAAGTAGAAAAAGGACCTGAATGATCATTGTGGTACTTAT
TCCCACGCATAACCGACTACGGCACCACAACGACGCACCA
Chr coordinates Chr X from 467033-466521
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