Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
ESS1
Systematic Name
YJR017C
Alias
PIN1, PTF1
Strain
S288c
Description
Peptidylprolyl-cis/trans-isomerase (PPIase); specific for phosphorylated S/T residues N-terminal to proline; regulates phosphorylation of RNAPII large subunit (Rpo21p) C-terminal domain (CTD) at Ser7; associates with phospho-Ser5 form of RNAPII in vivo; present along entire coding length of genes; represses initiation of CUTs; required for efficient termination of mRNA transcription, trimethylation of histone H3; human ortholog PIN1 can complement yeast null and ts mutants
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>ESS1 YJR017C
ATGCCATCTGACGTAGCATCGAGGACCGGGCTGCCAACCCCGTGGACCGTCAGGTATAGT
AAGTCCAAGAAAAGAGAGTATTTTTTCAATCCAGAGACGAAGCACTCGCAATGGGAGGAG
CCTGAGGGCACCAACAAGGACCAGCTACACAAGCACTTAAGAGACCATCCAGTGCGTGTA
AGATGCCTGCACATTCTCATCAAGCACAAGGATTCAAGAAGACCCGCATCGCATAGATCC
GAGAACATTACGATATCCAAGCAAGACGCTACGGACGAACTGAAAACCTTAATCACGAGG
TTGGATGACGACTCTAAGACGAACTCCTTCGAGGCCCTGGCTAAAGAGAGATCAGATTGC
TCTTCATACAAGCGAGGCGGCGACCTCGGCTGGTTCGGGAGAGGCGAGATGCAGCCTAGC
TTTGAAGACGCTGCCTTCCAGCTCAAGGTCGGCGAGGTAAGCGATATCGTTGAATCAGGA
AGCGGTGTTCATGTGATCAAGCGGGTAGGTTAG
Promoter Sequence
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>ESS1 YJR017C
TGTGCAGAATCTGAGAAACGGTAGAAATTTCATCCATAAGCAGGTTAGTGCTTATCAGCA
CGACAAGTTGATATTTACGTCGATGATCTTATTTGCCGTGCAACGGTCCAAGGAGCACGA
CTCCTTGCAGCACTGGGAGACGATTCCAGGCCTGCAAGGTAAGCAGCCAGACCCTCATCG
TTATGAAGAGGCCACTTCGCTTTTCCAGAAAGAAGTTCTGGACCCACAGAAATTGAGCAG
GTATGCCTCATTGTCCGACAGGTTCCAAGACGCAACCTCGATGAGCAAGTATGTGGATGC
GTTTCAATACGGAGTCATGGAGTACCAATTCCCCAAGGACATGTTCTACTCGGCAAGACA
CACCGACGAGCTGGATTATTTCGTCAAAGTGAGACCTCCCATCACTACCGTGGAGCACGC
GGGCGACGAGTCTTCTTTACACAAGCATCATCCGTACAGGATCCCGAAGAGCATTACTCC
TGAGAACGACGCTCGCTACAACTACGTGGCCTTTGCGTATCTGTCCGATTCCTACCTCCT
ACTCACGATCCCGTACTTCCACAACCTGCCTTTGTACTGCCACAGTTTCAGTGTCTCGCT
CGACCACACGATTTACTTTCACCAGTTGCCTCATGTGAACAATTGGATCTATCTTAAGAT
TTCGAATCCCAGGTCCCACTGGGACAAGCACCTCGTACAGGGCAAGTATTTCGACACACA
GTCGGGACGCATCATGGCAAGCGTCTCTCAGGAGGGCTACGTTGTCTACGGGTCAGAACG
AGACATTCGAGCCAAGTTCTGAGGACAATTCCCTCCCACGTATAAACACATACATATATA
TTCTTATATTATATAATAATATCCTATTTATTATTACATCACCTTTCACGAGCGGGTATC
ATACCTTTTTCCCTTCGATCTAAGTAGAAAAAGGACCTGAATGATCATTGTGGTACTTAT
TCCCACGCATAACCGACTACGGCACCACAACGACGCACCA
Chr coordinates
Chr X from 467033-466521