Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
CBF1
Systematic Name
YJR060W
Alias
CEP1, CP1, CPF1, GFII
Strain
S288c
Description
Basic helix-loop-helix (bHLH) protein; forms homodimer to bind E-box consensus sequence CACGTG present at MET gene promoters and centromere DNA element I (CDEI); affects nucleosome positioning at this motif; associates with other transcription factors such as Met4p and Isw1p to mediate transcriptional activation or repression; associates with kinetochore proteins, required for chromosome segregation; protein abundance increases in response to DNA replication stress
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>CBF1 YJR060W
ATGAACTCTCTGGCAAATAATAATAAGCTTTCTACTGAGGATGAGGAAATCCATTCGGCA
AGAAAAAGAGGCTATAACGAGGAGCAGAACTACAGCGAGGCCAGGAAAAAGCAAAGAGAT
CAAGGCTTGTTGTCACAAGAGAGCAATGACGGAAATATTGACTCTGCTCTGTTGAGCGAA
GGGGCTACGCTAAAAGGGACTCAAAGTCAGTATGAAAGCGGACTGACGTCTAACAAAGAT
GAGAAAGGAAGTGATGACGAAGATGCGTCAGTGGCTGAGGCTGCTGTTGCCGCTACCGTC
AATTATACAGACTTAATCCAGGGCCAGGAAGATAGTTCTGATGCCCACACATCTAATCAA
ACGAACGCGAATGGTGAGCACAAGGATTCCCTTAATGGGGAAAGAGCCATAACCCCATCA
AATGAAGGAGTCAAGCCAAACACCTCCCTGGAGGGAATGACGTCTTCACCAATGGAATCT
ACACAGCAATCTAAAAACGACATGCTCATACCATTGGCAGAACACGATCGTGGGCCAGAA
CACCAACAGGATGATGAAGACAATGATGACGCTGACATTGATCTCAAAAAGGATATAAGC
ATGCAGCCGGGTCGTCGTGGAAGAAAACCTACTACTTTGGCCACAACAGACGAGTGGAAA
AAGCAAAGAAAAGACTCCCATAAAGAAGTCGAAAGGCGTCGCCGCGAAAACATCAACACT
GCAATCAACGTTTTAAGCGACCTCCTGCCCGTGAGAGAATCAAGTAAGGCAGCAATATTG
GCGTGTGCCGCTGAATACATTCAAAAATTGAAAGAAACCGATGAAGCAAACATCGAAAAG
TGGACGTTACAAAAATTGCTTAGCGAGCAAAACGCATCGCAATTAGCCAGTGCAAATGAG
AAACTGCAGGAAGAACTGGGAAATGCTTACAAAGAAATCGAGTACATGAAACGCGTTTTA
AGGAAGGAGGGAATAGAATACGAGGATATGCACACTCACAAGAAACAAGAGAACGAAAGA
AAAAGCACTAGGAGCGATAATCCACATGAGGCTTGA
Promoter Sequence
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>CBF1 YJR060W
GCACCAAACCTAAGCAGCAAGATAAAAAGGAAAATTTGAAGAAAGATGAGGTCAAGAACG
GCGACAAGGACAAAGTCATTGAAGAGGCTACCACGACTAATGTGGACAGCATATTGGAAA
AACCAACACCAACCTCCACAAAAGTAGAGGACAACTTAAGCGAAGATGATTCCACAATGA
AGGAATTAAAGTCGATGCTAAACTCCACCCCTACTACACCAACACATAATGGCCCCACTC
CGCTCCCTGCAAAGGCTGGCACTCAATTAGATAAGCGTATGAGCGACCTATCACTCAAAT
CGGAAACACCGGCTTCTACAAAGAACTTTAGCGCACCGAATGTTTCGTCATCAAGCAATT
CACTGAGAAGCCTCGGAAGTCCAAGCGTGTCATCCTCGAAAAAGAAGAAGGTAATTCACC
ACCACTTGGACATTACCAACAGCGTTACAAACATGTCATCCGTGAGCGCCTTTATCTCAA
GATAGACGTTAGGACTTCTTTAATTCCCTCTTTTATGCTTTAGTATCGTCATATTCTTTC
ATACCCTTCCTTATAAGCTTTTTATATAAAATATCCCACCGGGAAAAGATAAAGAACGGA
AGATAAATCAAACAATGAAATAAAGCACACACATATAAATCCACATATGTACTTATATAT
TTTACTTCAAACAATAAACAAACATTTTATTATTTATTTTTCCCGTACATCGATGTACGT
GATCGGTTTTTCTCATTCCTCTCGGATCCTTCGGGACCACCATGTCTCACCCACCAAGGT
CAAAAAAAAAATAAAATCGGACGAGAAAAGTATTGGGCAAACAACAATTATCCACGTGCT
TATCACGTTTTTTTATTTAATGTAGAATGTAAACCATTATACCTTAAAGATAAACACTTT
GTTAATTAATCATTTTAGTTGGCGGTCATTTTCATTTCTGCTACAAGTACCAACATCAAG
TGCTTAAAATATAATACGGTTTTCTACACTTTTATTAACG
Chr coordinates
Chr X from 548759-549814