Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Standard Name
HAM1 Systematic Name
YJR069C Strain
S288c Description
Nucleoside triphosphate pyrophosphohydrolase; active against various substrates including ITP, dITP and XTP; mediates exclusion of non canonical purines, pyrimidines from dNTP pools; functions with YJL055W to mediate resistance to 5-FU; specifically reduces the incorporation of 5-FU into RNA without affecting uptake or incorporation of uracil into RNA; protein abundance increases in response to DNA replication stress; yeast HAM1 can complement knockdown of human homolog ITPA External sources
Open in SGD
Open in KEGG
Gene Sequence
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>HAM1 YJR069C
ATGAGCAACAACGAAATTGTATTTGTCACTGGCAATGCCAACAAGTTAAAGGAAGTGCAG
TCGATTTTGACTCAAGAGGTCGACAACAACAACAAAACCATCCACTTAATCAATGAGGCC
TTAGACCTGGAAGAATTGCAGGACACGGATCTGAATGCCATTGCGTTAGCTAAGGGAAAG
CAAGCTGTTGCGGCCTTGGGTAAGGGTAAGCCAGTGTTTGTGGAAGACACTGCGTTGAGA
TTTGACGAATTTAACGGTCTACCAGGTGCTTATATAAAATGGTTTTTAAAGAGCATGGGA
TTGGAAAAAATTGTGAAAATGTTGGAACCCTTTGAAAATAAAAACGCTGAAGCAGTTACC
ACCATTTGTTTTGCTGATTCTCGGGGTGAATATCACTTCTTTCAAGGTATTACAAGAGGC
AAGATCGTTCCAAGCCGGGGACCCACTACATTCGGCTGGGATTCAATTTTTGAACCTTTT
GATAGTCATGGACTGACTTACGCAGAGATGAGCAAAGACGCAAAGAATGCTATTTCTCAT
CGTGGTAAAGCCTTCGCTCAGTTTAAAGAGTACTTGTATCAAAATGACTTTTAG Promoter Sequence
Download FASTA
>HAM1 YJR069C
AATCCTTCGTCAATGACAAGTCTGAGTTGTTGAAGCACGAAGTGGCCTACGTGTTGGGTC
AAACCAAGAACTTGGACGCTGCTCCAACTTTAAGACACGTTATGTTAGATCAAAATCAAG
AACCAATGGTGAGACACGAAGCCGCTGAGGCTTTGGGTGCCCTAGGTGACAAGGATTCGT
TGGATGACCTAAATAAGGCTGCTAAGGAGGATCCACACGTTGCTGTGAGAGAAACCTGTG
AACTGGCCATTAACAGAATCAACTGGACCCATGGAGGTGCCAAGGATAAGGAAAACTTGC
AACAATCCCTATACTCGAGTATTGACCCAGCCCCACCTCTACCATTAGAAAAGGATGCTA
CCATCCCAGAACTACAGGCCTTATTGAATGATCCTAAGCAACCTTTGTTCCAAAGATACA
GAGCCATGTTCAGACTGAGAGATATCGGTACTGATGAAGCAATCCTGGCCTTGGCCACTG
GTTTCAGTGCAGAATCCTCCCTTTTCAAGCATGAAATCGCCTACGTCTTCGGTCAAATAG
GTAGTCCGGCTGCTGTCCCAAGTTTGATTGAAGTTTTGGGCAGAAAGGAAGAAGCTCCAA
TGGTTAGGCATGAAGCTGCTGAAGCCTTGGGTGCCATTGCTTCTCCAGAAGTTGTCGACG
TCTTGAAATCTTACCTCAACGATGAAGTCGATGTCGTCAGAGAATCTTGTATCGTTGCGC
TAGATATGTATGATTACGAAAACAGCAACGAACTAGAATATGCTCCAACTGCTAATTAGA
AGAATCAGCATCATCAATAATGATAGTAACAATAATCATTGTATAATCTTGTATTTTATA
CTTTTCAAAACCCGCCATTTCCGTTATATATACAAATGTATCAAATAGCAAAAAAATTAT
TTATTTTCGAAACCGTTCTCTCGAGCTTCAGCTTTCAACACTGGTCTTCAAAGCATAGGA
AACACTCACATAGAGATATCTAAAAACGAACGATAGCAGA
Chr coordinates
Chr X from 569399-568806
