Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name BNA2
Systematic Name YJR078W
Strain S288c
Description Tryptophan 2,3-dioxygenase or indoleamine 2,3-dioxygenase; required for de novo biosynthesis of NAD+ from tryptophan via kynurenine; up-regulated by telomere uncapping, and interacts genetically with capping gene CDC13; overexpression reduces lipid droplet accumulation by skewing glycolytic flux towards biosynthesis of shikimate, aromatic amino acids, and NAD+ during aging and extends lifespan; regulated by Hst1p and Aftp
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Gene Sequence
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Promoter Sequence
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>BNA2 YJR078W
AGGCGGTATCGTAACCCAAGTTGTCAATGAAGAACTTCTTGAACACTTCGTAACCACCGA
ACTTGAAGGCACCTTGGATAGAGTAACCCAACAAAGTAGGACCAAACCCGGTCAACAACG
CACCAGCACCTTCTCCGGCGATGATTTGCTTGAAAGAGCCGACCATACCCTTGTTGTACA
CGGTAGGTTCCAGTTGGATTCTCGTCTTAACGACATCGATCGGGACCATACTGGAGTGAG
TCGACCCGCACCCTATGGCGCCGGCTAGGGCGAATTTCATGTAGTCAGAGACAGAGTACT
GTGGAATAGCAGGAGCAGCAGACACAGACATGGTGAGATGAGACTTTTTGATCTTTGTAG
TTCTTCTTCTTGCAGATCACTCTGTTCTTTGCGATGGTTCTTGTAGATAAAAAGATCGGG
AGGATGGATCGCACTTAAAAATCTTCTCGAAACGGGCCGCGGCCGGGCATGGGACCCGTT
CTCGACGCTGATTGGCTAACGATGGTTGGGCAGAGTCTCAGCTGCTGCTTGCTCACATTC
GACAAAAGACTAGAGGAAAGCAGTACCATGCTGCGATACTGTTGCATCGCAGCATTCCGC
TGTCCAAAAACAATACCTGTTGTATTGTTTGAGGCTGGCAGGCGCTTGGGTAGAAACAAC
ACCCGATACTGGTGACAGGGCTATCTATAAATATTAAAACTTGACTCCGCAATTCGTCGT
AAACTGCCTTAACCATCGTAATGGACGCCGTGCAAATGCTTCGACTTTTCCCAGTAGTCA
GGCATTGCGCCAGACACTTGTGCTGCTTAATTGTCGTAATGAAAACATATCGGTAGCGGC
CTTTTTTTATTTTTTTTCTCTATGGGCTGACGCTGTCACTTTTCAACGTCGCTCCGAGGC
AAAAAAGCCACCGTCAGAAATAATTACTGTCACACACACTAGATGTCCATGTATCTTTAG
CATATATAAAGCGAAAATAAAAGAAAGAGTCAACGCCGAT
Chr coordinates Chr X from 578860-580221
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