Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
JHD2
Systematic Name
YJR119C
Alias
KDM5
Strain
S288c
Description
JmjC domain family histone demethylase; promotes global demethylation of H3K4 and repression of noncoding intergenic transcription during sporulation; removes methyl groups added by Set1p; negatively regulated by H3K14 acetylation; protein levels regulated by Not4p polyubiquitin-mediated degradation; regulates sporulation timing by extending period of active transcription; regulates rDNA silencing; human homolog is JARID1C
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>JHD2 YJR119C
ATGGAGGAAATTCCTGCCCTGTATCCAACGGAACAAGAATTCAAAAATCCGATCGATTAT
CTCTCTAACCCCCACATTAAAAGGCTTGGTGTACGATATGGTATGGTCAAGGTCGTACCA
CCAAACGGGTTCTGCCCGCCACTTTCTATTGATATGGAAAATTTTACTTTTCAACCAAGA
ATTCAAAATCTGGAGAACCTAGACCTGAAAAATAGGTGTAGGCTATTTTTTATGAAACAG
TTAAATAATTTTAAAAGATCCGTTAAGGATCCATCGAAACTTATACTTAGGGAACCTTAT
ACGATTGTAGAATATTCAGATTCTACTCATGCATCGGAAATACTAAAAAAAAAAGTGTAC
TTTTATGACGTTTTCTCTGAACTAATAAAAGACAATCGGACACTTACTGACACTACACAG
TCATTCAGGCGAAAATTGAAATTTAGAGATATTTCCCAATTAAGAGGCGACATCAGTCTA
TGGAGGACCATTTCTAAAAAATTCAACGTACCAATCGGCTTGTTAAAGGAAATTTTTGAG
AAATATATTGCCTCATACTACATATTTCTTCATTCACTGAACGAGAACGTGCACACGGCG
CTGCATGCTGACCAGTATCCAAAATCCTTATTAAGTGATGACGAGGACGATTTCGATCTT
GGGCCAGATTCGAATTCTGGGTCGGATTTTGAGGAGGACGATGATGATGCTTGTATTGTT
TGTCGCAAGACAAATGATCCAAAAAGAACAATTTTATGTGATTCATGTGACAAACCATTC
CATATATATTGTTTATCACCACCTTTGGAACGTGTTCCCTCTGGCGATTGGATTTGTAAC
ACTTGTATCGTCGGAAACGGATATTACGGATTCACTCAGGACACGCATGACTATTCTCTA
CCAGAGTTTCAAGAATATTGTAAACGTCAAAATTCAAGGTTATTACCAGCACGAAAACTG
TCTATAGATGAGTTGGAAGAGATGTTTTGGAGCTTAGTGACCAAGAATCGTCGCAGTTCA
TTAACGACAGTTAAATACGGTGCTGACATACATAACGAATTGCCAGGTCAAATTACCGGC
TTTCCGACGAGAGAATTTATACCCAAAAATATAAATGGGGACGAATTGATAGACTACCTC
AAATATTGCGATCATCCTATGAATTTAACTAACTTGCCTATGGCTCATAATTCGCTATTA
CCGTTATTTAAAAGAAATATTTCTGGCATGACTATTCCTTGGATTTACATAGGCTCCTTA
TTTTCCACATTTTGTTGGCATATGGAAGATCAGTATACCCTAAGTGCTAACTATCAACAT
GAAGGTGACCCTAAGGTCTGGTACAGCATTCCCGAATCGGGATGTACGAAATTCAACGAT
CTATTAAATGATATGTCACCAGACTTATTTATCAAACAACCAGACCTACTGCATCAGCTA
GTGACTTTAATATCTCCGTACGATCCAAATTTCAAGAAATCAGGTATTCCTGTGTACAAA
GCTGTGCAAAAGCCCAACGAATATATTATCACGTTTCCTAAATGTTACCATGCTGGTTTT
AATACAGGTTATAATTTTAATGAAGCTGTCAATTTTACTATAGATTTCTGGCTACCATAT
GGATTTGGTGCGATTACGGATTATAAATTAACTCAGAAAGCATGTGTTTTTGATATGTTT
GATTTAATGATCAATGTTTTGGACAAGTACAATAAAGATACTCTATTGTTCAATGATGCT
TTTGTTAGGCAATGTTACTCTTCATTGATCGTCTTTTATAATACTGAATTAAAACGCATA
CGGAAAATTCAGGCCATTGTACCACGGACAACTCTTTTGGAGGTGCATACTGATCCAAAC
GATGAAGATGAGGAATACGATATATTTTGTTCCCAATGTAAGACTATATGTTCAATAGCC
TTTGTATTGCGAAAGAATAACTATGATTCAATTAGAACGTATAAAAGACACAAGAAAAAC
CATTTAAGTATTAGGCAGTGGAATGAACTATCCACGACGGACAGTAAAGTGAGTATCCTG
TGTACGCAGGATTACTTAAAATCAATACAAAACTTGAACAATAGCGACGGTGAAGAACCT
TATATTGACGATGAATTGTATTTCACTAAGTCTTTGAAGGATATTGACTCTTTAATAAAG
CAAGTTGGTGTTAAGTTAGATAGATAG
Promoter Sequence
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>JHD2 YJR119C
TTTATGAGGGGGGTTTAGGTTGCTAAAATTTGTGTTACTGTTTGATCTTTGCAAAATTTA
TCCAATTGGCCTGTCCTGGAGAGATAAAGAAAGTTTAAAAAAGGGCAAGTTAAAATGTTT
GTTCTGTAATACAAAAAAGAGGTTAATGCAAAAAGTGCGTTCTTTATAAGCGTTGTATCT
AAGAGCTCGAAGATGGGAATATCCTTGCGCTGCTTGGCCGGCGAGGGGCCCACCCGGCAC
GCGCTTGGAGGTCGCCGTTGATTGGCCGCTATATATCGCGAATCACGGGGGTGTGTGTGC
GACCCGGTGCGCCGGGTGGCATATGGGCGGCTAATTGCGTATAAGATGATAACATCCCAG
CGCATCACGTGAAAGGAAATACATATATATGTGGCTTTATTACTGGTTTAGAGTATTTTT
GTACTGTGACTACTACTGTATTTCATGTAGCAGAATACACAGCCTTTTACTTCTGTTCTT
TCTCAAAGGTTCAAGAAATAGAATAGCCAAGTGCCATCAAGAACTCGAACTAACTTTCGT
AGAAGGAGTAGTATACAGTCTTGCTTGTCACAACTCTTTCAGGAGCTTTCTTTTTAGTAT
TATACACGATCCGTATGCTCATCTCGTGATATAGAAGTAACGCATTGAATGCAAAGAAAG
GCAGATATTTTACCCTAGGTGTAACCAGAAGAGATTAGGAGGGCTTAGGGCCAGTATTTT
ATCTGATGTAGGGCAAACGAGTAAAATGTGTAGGGTATGGGCTAATATCAAGGGCTTCGG
ACTTACTGCCCCGCTCACAGAAACAGCCGCACTAATTAATTTCTTTTGTGTAACGTTAAA
GTAACCCTGGAATCATCATTGAAAAATTATCATCCCAAGAGACAGAGATGTGCATGTTGA
CAACGCAGGCTCAATGTAGAATAAGATCTGACTACTTAGTCAATTTTACCTCTAGATCAT
ATTAACTAATCTCATCTTGCACAAAAAACGTATCACTATC
Chr coordinates
Chr X from 646490-644304